Results 61 to 70 of about 1,623,110 (217)

Comparative Effects of Clinical Pilates Training and Aerobic Exercise on Menopausal Symptoms, Quality of Life, Sleep and Depression: A Randomised Controlled Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine the effects of Clinical Pilates (CP) training and aerobic exercise (AE) on menopausal symptoms, depressive symptoms, quality of life (QoL), and sleep quality in postmenopausal women. Design Parallel‐group randomised controlled trial. Setting A Healthy Life Center in Bitlis, Turkey.
Başak Can, Serkan Usgu, Günseli Usgu
wiley   +1 more source

Dynamics of Descending Inhibition and Neuroendocrine Analgesia with special reference to the Trigeminal region [PDF]

, 2011
In patients with pain, it is of relevance to use clinical assessments that evaluate the pain modulation. In this thesis, the dynamics of descending inhibition or central sensitization and neuroendocrine analgesia were investigated: in healthy ...
Feldreich, Anna
core   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Increased β‐endorphin and autotaxin in patients with prurigo

Journal of Cutaneous Immunology and Allergy, 2019
Objectives Prurigo is a treatment‐resistant inflammatory disease of unknown etiology. Persistent and severe itch is a major and important clinical symptom, but pathological mechanisms and/or actual mediators for itch in prurigo remain to be defined ...
Takahiro Ishikawa, Takashi Hashimoto, Takichi Munetsugu, Hiroo Yokozeki, Takahiro Satoh   +4 more
doaj   +1 more source

Salivary biomarkers of HPA axis and autonomic activity in adults with intellectual disability with and without stereotyped and self-injurious behavior disorders [PDF]

, 2011
Salivary levels of biomarkers for the hypothalamic–pituitary–adrenal axis (HPA; cortisol) and sympatho-adreno-medullary system (SAM; α-amylase) were measured in 51 adults (57% male) with neurodevelopmental disorders associated with intellectual ...
Frank J. Symons, Jason J. Wolff, Laura S. Stone, Tony K. Y. Lim, James W. Bodfish   +4 more
core   +2 more sources

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Curcumin Exerts Antinociceptive Effects in Cancer-Induced Bone Pain via an Endogenous Opioid Mechanism

Frontiers in Neuroscience, 2021
Cancer pain is one of the main complications in advanced cancer patients, and its management is still challenging. Therefore, there is an urgent need to develop novel pharmacotherapy for cancer pain.
Guanghai Zhao, Guanghai Zhao, Guanghai Zhao, Yongqiang Shi, Yongqiang Shi, Yongqiang Shi, Chaoyang Gong, Chaoyang Gong, Chaoyang Gong, Taicong Liu, Taicong Liu, Taicong Liu, Wei Nan, Lin Ma, Lin Ma, Lin Ma, Zuolong Wu, Zuolong Wu, Zuolong Wu, Chaoming Da, Chaoming Da, Chaoming Da, Kaisheng Zhou, Haihong Zhang, Haihong Zhang, Haihong Zhang   +25 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Milk removal in familiar and unfamiliar surroundings: concentrations of oxytocin, prolactin, cortisol and β-endorphin [PDF]

, 2017
Eight cows were machine milked either in an operating theatre or in their familiar barn. During the experiments, milk flow curves were recorded and blood samples were taken for determination of concentrations of oxytocin, prolactin, cortisol and β ...
Blum, Jürg W., Bruckmaier, Rupert M., Schams, Dieter   +2 more
core  

Scalable Production of Highly-Sensitive Nanosensors Based on Graphene Functionalized with a Designed G Protein-Coupled Receptor [PDF]

, 2014
We have developed a novel, all-electronic biosensor for opioids that consists of an engineered mu opioid receptor protein, with high binding affinity for opioids, chemically bonded to a graphene field-effect transistor to read out ligand binding.
Crook, Alexander, Han, Gang Hee, Hong, Sung Ju, Johnson, A. T. Charlie, Lerner, Mitchell B., Liu, Renyu, Matsunaga, Felipe, Park, Yung Woo, Perez-Aguilar, Jose Manuel, Saven, Jeffery G., Xi, Jin   +10 more
core   +4 more sources