Trazodone influence on rat sera beta-endorphins level
Some 25 years ago it was found that parts of CNS could produce strong analgesic response on little morphine quantities. Later studies proved the existence for dozen of morphine-like substances, called opioids, which are normally produced in the brain ...
Radivoj Jadrić +7 more
doaj +2 more sources
ß-endorphins as Possible Markers for Therapeutic Drug Monitoring [PDF]
This study was performed in order to investigate possible role of brain beta-endorphins as markers of antidepressive drugs therapy monitoring. Experiment was done using amitriptyline and trazodone as antidepressants.
Radivoj Jadrić +3 more
doaj +2 more sources
DYNAMICS OF LEVEL B-ENDORPHINS AT MODELLING OF THE ISCHEMIC STROKE AT RATS [PDF]
The problem of treatment of the ischemic stroke (IS) is actual in modern medicine. In work an attempt of creation of model of cerebral ischemia at rats with possibility of application of TES-therapy is made.
A. I. Trofimenko +5 more
doaj +1 more source
The Endogenous Opioid System in Compulsive Eating [PDF]
Background/Objectives: The rates of obesity and binge-eating disorder (BED) have increased markedly over the last few decades. The onset of these conditions has been associated in part with the disruption of neural pathways that regulate food reward ...
Aneesha Janbandhu +8 more
doaj +2 more sources
Neurotransmitter Imbalance in Tension-Type Headache: A Systematic Review of Mechanisms and Therapeutic Targets [PDF]
Introduction Tension-type headache (TTH) is the most prevalent primary headache disorder worldwide, yet its neurobiological underpinnings remain partially understood.
Lanfranco Pellesi +6 more
doaj +2 more sources
Effects of wet cupping in a rat model of primary dysmenorrhea [PDF]
Background: Primary dysmenorrhea (PD) is characterized by discomfort with no organic etiology (no pelvic disease), recurring pain, or lower abdominal cramps that start between the first 8–72 h of menstruation. Cupping therapy uses a tool to form a vacuum
Sri Lestariningsih +6 more
doaj +2 more sources
Chronic low back pain management: clinical and psychophysiological outcomes of multimodal approaches—a randomised controlled trial on yoga and mindfulness [PDF]
Chronic low back pain (CLBP) presents as a widespread medical issue which severely affects personal health status while generating substantial economic expenses.
Basit Ansari +3 more
doaj +2 more sources
Hypophysectomy, pituitary neuroadenolysis and pituitary radiosurgery for the treatment of refractory cancer pain: a historical review and mechanism investigation [PDF]
Refractory cancer pain affects 10–20% of patients with advanced malignancies and is not adequately controlled by opioids. The intrathecal therapy is an effective interventional procedure for referral, but the implanted infusion pumps are costly and the ...
Yuchen Hu +27 more
doaj +2 more sources
Microbiome and metabolomic changes in rabbits induced by Folium sennae. [PDF]
Diarrhea is a serious health concern in livestock, affecting productivity and animal welfare. However, it remains a significant threat. Various practical therapies are being explored, such as prebiotics, probiotics, and organic acids, as well as chemical
Houkang Ding +8 more
doaj +2 more sources
Effect of physical exercise on pain thresholds and plasma beta-endorphins in patients with silent and symptomatic myocardial ischaemia [PDF]
In a double-blind study, eight patients with symptomatic myocardial ischaemia and nine with asymptomatic myocardial ischaemia were compared during physical exercise under naloxone (6 mg i.v.) or placebo. Plasma beta-endorphin, cortisol and catecholamines
Roskamm, H. +3 more
core +1 more source

