Results 21 to 30 of about 43,839 (148)

β-Glucan Induces Training Immunity to Promote Antiviral Activity by Activating TBK1

Viruses, 2023
Many studies have shown that β-glucan induces a trained immune phenotype in innate immune cells to defend against bacterial and fungal infections. The specific mechanism involves cellular metabolism and epigenetic reprogramming.
Guolei Wang, Zhiqiang Li, Mingfu Tian, Xianghua Cui, Jun’e Ma, Siyu Liu, Chenglin Ye, Li Yuan, Muhammad Suhaib Qudus, Uzair Afaq, Kailang Wu, Xinghui Liu, Chengliang Zhu   +12 more
doaj   +1 more source

Characterization of cereal β-glucan extracts from oat and barley and quantification of proteinaceous matter. [PDF]

PLoS ONE, 2017
An extraction method for mixed-linkage β-glucan from oat and barley was developed in order to minimize the effect of extraction on the β-glucan structure.
Claudia Zielke, Ondrej Kosik, Marie-Louise Ainalem, Alison Lovegrove, Anna Stradner, Lars Nilsson   +5 more
doaj   +1 more source

Glucan and glycogen exist as a covalently linked macromolecular complex in the cell wall of Candida albicans and other Candida species

The Cell Surface, 2021
The fungal cell wall serves as the interface between the organism and its environment. Complex carbohydrates are a major component of the Candida albicans cell wall, i.e., glucan, mannan and chitin.
Douglas W. Lowman, M. Sameer Al-Abdul-Wahid, Zuchao Ma, Michael D. Kruppa, Elena Rustchenko, David L. Williams   +5 more
doaj   +1 more source

Association of immunological disorders in lethal side effect of NSAIDs on β-glucan-administered mice [PDF]

FEMS Immunology & Medical Microbiology, 2001
(1-->3)-beta-D-Glucan (beta-glucan) is a biological response modifier that regulates host immune response. We have found that the combination of a beta-glucan and a non-steroidal anti-inflammatory drug (NSAID), indomethacin (IND), induced lethal toxicity in mice [Yoshioka et al. (1998) FEMS Immunol. Med. Microbiol., 21, 171-179].
H, Takahashi, N, Ohno, Y, Adachi, T, Yadomae   +3 more
openaire   +2 more sources

Gradual solubilization ofCandidacell wall β-glucan by oxidative degradation in mice [PDF]

FEMS Immunology & Medical Microbiology, 1998
Candida spp. is a medically important fungi which induces disseminated candidiasis and candidemia in hospitalized immunocompromised patients. The cell wall of Candida is mainly composed of two polysaccharides, mannan and beta-glucan, and at least part of beta-glucan is basically insoluble in H2O or NaOH. We became interested in when and how particulate
N N, Miura, T, Miura, N, Ohno, Y, Adachi, M, Watanabe, H, Tamura, S, Tanaka, T, Yadomae   +7 more
openaire   +2 more sources

Protective effect of β-glucan against systemicStreptococcus pneumoniaeinfection in mice [PDF]

FEMS Immunology & Medical Microbiology, 2000
The antimicrobial effect of soluble beta-1,3-D-glucan from Sclerotinia sclerotiorum (SSG) was examined in mice experimentally infected intraperitoneally (i.p.) with Streptococcus pneumoniae serotypes 4 and 6B. SSG was administered i.p. either 3 days before challenge or 3-48 h after challenge.
G, Hetland, N, Ohno, I S, Aaberge, M, Lovik   +3 more
openaire   +2 more sources

Characterization of an unglycosylated low molecular weight 1,4-β-glucan-glucanohydrolase ofTrichoderma reesei [PDF]

FEMS Microbiology Letters, 1990
A low molecular weight endoglucanase (1,4-beta-glucan glucanohydrolase E.C.3.2.1.4) was purified to homogeneity by a two-step procedure from 7 day old culture filtrates of Trichoderma reesei. The endoglucanase was obtained by BioGel A 0.5 m gel chromatography followed by preparative PAGIF. The purified endoglucanase was homogeneous upon titration curve
A, Ulker, B, Sprey
openaire   +2 more sources

Purification, Preliminary Structural Characterization, and In Vitro Inhibitory Effect on Digestive Enzymes by β-Glucan from Qingke (Tibetan Hulless Barley)

Advances in Polymer Technology, 2020
Background and Objective. Qingke (Tibetan hulless barley, Hordeum vulgare L.) contains a high content of β-glucan among all the cereal varieties. Although β-glucan has multiple physiological functions, the physiological function of qingke β-glucan was ...
Jialiang Hu, Yue Wu, Huifang Xie, Wanyin Shi, Zhiyuan Chen, Dan Jiang, Hui Hu, Xiangwei Zheng, Jian Xu, Yuejun Yang, Yuancai Liu   +10 more
doaj   +1 more source

Stimulation of human neutrophil phagocytosis ofCandida albicansby a β-glucan synthase inhibitor, cilofungin [PDF]

FEMS Microbiology Letters, 1991
The effect of a lipopeptide antifungal agent, cilofungin, on serum opsonization and phagocytosis of Candida albicans yeast phase cells in human neutrophil monolayer assays was investigated. Simultaneous addition of fungicidal concentrations of cilofungin did not enhance or inhibit phagocytosis of C. albicans.
Richardson, M D, Smyth, L A, Shankland, G S   +2 more
openaire   +3 more sources

β-Glucan, extracted from oat, enhances disease resistance against bacterial and parasitic infections [PDF]

FEMS Immunology & Medical Microbiology, 2003
The effect of beta-glucan, extracted from oats, on the enhancement of resistance to infections caused by Staphylococcus aureus and Eimeria vermiformis was studied in mice. In vitro study using macrophages isolated from the peritoneal cavity showed that beta-glucan treatment significantly enhanced phagocytic activity.
Cheol-Heui, Yun, Alberto, Estrada, Andrew, Van Kessel, Byung-Chul, Park, Bernard, Laarveld   +4 more
openaire   +2 more sources