Results 161 to 170 of about 61,189 (311)

The development of type 2 diabetes amongst sibling pairs in the South‐South region of Nigeria: The effect of genetics, environment and lifestyle

Diabetic Medicine, EarlyView.
Abstract Introduction Type 2 diabetes is a complex condition with a multifactorial pathogenesis. The pathogenesis is considered to be polygenic due to complex interactions between genetic/epigenetic and environmental factors. The aim of this study is to determine the genetic, environmental and lifestyle factors associated with the development of type 2
Sunny Chinenye, Ibi Erekosima, Adrian H. Heald, Gesiye Bozimo, Simon G. Anderson, Samuel Seidu, Kariba Akhidue, Adaeze Ugwu, Chioma Unachukwu, Ibitrokoemi Korubo, Kingsley Chukwuemeka Patrick‐Iwuanyanwu, Victoria Gomba, Uwoma Batubo, Victoria Akanatei, Victor Ken‐Uba, Iyeopu Siminialayi, Sokiprim Akoko, Justin Ideozu, Hamilton Opurum   +18 more
wiley   +1 more source

MOESM1 of A novel GH10 xylanase from Penicillium sp. accelerates saccharification of alkaline-pretreated bagasse by an enzyme from recombinant Trichoderma reesei expressing Aspergillus β-glucosidase

, 2017
Additional file 1: Figure S1. Multiple alignments and phygogenetic tree of PspXyn10, PspXyn10 orthologs and TrXyn3. (a) Multiple alignments of the PspXyn10, PspXyn10 orthologs and TrXyn3. The amino acid sequence of PspXyn10 was compared with those of endo-1,4-beta-xylanase from Penicillium brasilianum (OOQ87260), endo-1,4-beta-xylanase D from ...
Shibata, Nozomu, Suetsugu, Mari, Kakeshita, Hiroshi, Igarashi, Kazuaki, Hagihara, Hiroshi, Takimura, Yasushi   +5 more
openaire   +1 more source

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang, Menghan Li, Manrong Xu, Yun Shen, Lianxi Li, Gang Hu   +5 more
wiley   +1 more source

Dementia Risk in Type 1 and 2 Diabetes: A Nationwide Population‐Based Comparison

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Diabetes is increasingly recognised as a major contributor to cognitive decline and dementia, but the risk varies by diabetes type and treatment intensity. We compared the risk of all‐cause dementia, Alzheimer's disease (AD) and vascular dementia (VaD) among individuals with and without diabetes.
Ji Eun Jun, Seohyun Kim, In‐Kyung Jeong, Jae Hyeon Kim   +3 more
wiley   +1 more source

Discovery of a cryptic aminoacidic triad involved in the temperature adaptation of GH1 enzymes

The FEBS Journal, EarlyView.
Cold‐active enzymes retain high catalytic activity at low temperatures but are characterized by thermal instability, a behavior not fully understood. Comparison between a cold‐active GH1 and its mesophilic counterparts highlights the role of a three‐residue motif (W‐M‐F) in conferring structural stability to a mesophilic GH1.
Stefania Digiovanni, Gabriel Oanca, Marco Orlando, Marina Lotti, Johan Åqvist, Marco Mangiagalli   +5 more
wiley   +1 more source

Co-optimization of xyloglucanase and beta-glucosidase using response surface methodology [PDF]

, 2015
Xyloglucanase and beta-glucosidase are important accessory enzymes required for hydrolysis of lignocellulosic biomass. In an effort to reduce the cost of production, tamarind kernel polysaccharide was used as the substrate for production of both enzymes.
Rashmi, R., Siddalingamurthy, K.R.
core  

Diabetic foot ulcer‐related amputation is associated with twofold increased risk of cardiovascular disease: A Korean National Health Information Database Study

Journal of Diabetes Investigation, EarlyView.
Data/Design: Nationwide, population‐based longitudinal cohort using the Korean National Health Insurance Service health checkup database (index 2009–2012) with follow‐up through December 31, 2018. Population/Exposure: Adults with diabetes (N = 1,229,689); DFU‐related amputation at baseline (n = 1,486) vs no DFU‐related amputation.
Jinsun Jang, Bong‐Seong Kim, Hye Won Yang, Heejun Son, Dong Yeon Lee, Min Gyu Kyung, Hwan Jun Jae, Saebeom Hur, Sang Wha Kim, Sanghyun Ahn, Kyung‐Do Han, Soo Heon Kwak   +11 more
wiley   +1 more source

Glycemic control and renal function decline in patients with chronic coronary syndrome: A multicenter cohort study

Journal of Diabetes Investigation, EarlyView.
Achieving HbA1c of 6.5–6.9% is associated with a reduced risk of renal complications in patients with diabetes and chronic coronary syndrome. Abstract Aims/Introduction Diabetes mellitus significantly contributes to renal complications, especially in patients with coronary artery disease (CAD).
An‐Yu Cheng, Chin‐Chou Huang, Hsin‐Bang Leu, Wei‐Hsian Yin, Wei‐Kung Tseng, Yen‐Wen Wu, Tsung‐Hsien Lin, Hung‐I Yeh, Kuan‐Cheng Chang, Ji‐Hung Wang, Chau‐Chung Wu, Jaw‐Wen Chen   +11 more
wiley   +1 more source

Titration curves of cellulases fromTrichoderma reesei: demonstration of a cellulase-xylanase-β-glucosidase-containing complex [PDF]

FEMS Microbiology Letters, 1983
B. Sprey, C. Lambert
openaire   +1 more source

Life‐threatening acute complications persist among individuals with type 1 diabetes in Japan: A nationwide registry‐based cross‐sectional study

Journal of Diabetes Investigation, EarlyView.
Despite insulin therapy, 18.8 and 7.8% of the patients experienced diabetic ketosis and diabetic ketoacidosis, respectively. Furthermore, 12.7 and 28.9% of the participants experienced severe hypoglycemia and hypoglycemic unawareness, respectively. Lower C‐peptide levels were associated with the incidence of these complications.
Daisuke Chujo, Akihisa Imagawa, Junnosuke Miura, Kazuma Takahashi, Toru Kikuchi, Ichiro Horie, Daisuke Yabe, Akira Shimada   +7 more
wiley   +1 more source