Results 101 to 110 of about 24,092 (167)
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.SC administration was associated with a longer elimination half‐life, mean residence time and mean absorption time, suggesting a slower absorption process compared with the IM route. In addition, systemic exposure, as reflected by AUC0–last and AUC0–∞, was lower after SC administration than after IM and IV dosing. ABSTRACT Objective Tolfenamic acid (TA)
Orhan Corum +11 more
wiley +1 more source
Clinical Genetics, Volume 110, Issue 1, Page 125-130, July 2026.We identify a female patient with a homozygous nonsense variant (p.Gln38Ter) in the LYSET gene. This is the first western report of a challenging case of an extensive diagnostic odyssey and demonstrates that the LYSET gene must be considered in the differential diagnosis when M6P‐labeled lysosomal enzymes are altered.
Fernanda Sperb‐Ludwig +5 more
wiley +1 more source
A New Paradigm in the Relationship between Gut Microbiota and Breast Cancer: β-glucuronidase Enzyme Identified as Potential Therapeutic Target. [PDF]
Pathogens, 2023 Fernández-Murga ML +3 more
europepmc +1 more source
The FEBS Journal, Volume 293, Issue 13, Page 3788-3813, July 2026.Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley +1 more source
The in vitro metabolism and in vivo pharmacokinetics of the bacterial β-glucuronidase inhibitor UNC10201652. [PDF]
Xenobiotica, 2022 Kerins A +8 more
europepmc +1 more source
Genes to Cells, Volume 31, Issue 4, July 2026.We identified a Mis4 cohesin loader mutant that is specifically defective in chromatin axis formation and homologous recombination while retaining normal sister chromatid cohesion. The mis4‐LR mutant, carrying the L1150S and R1159G amino acid substitutions, exhibited reduced interaction between Mis4 and Rec8, suggesting a meiosis‐specific role for the ...
Takeshi Sakuno +3 more
wiley +1 more source
Journal of Integrative Plant Biology, Volume 68, Issue 7, Page 2242-2263, July 2026.Abscisic acid signaling homeostasis is essential for seed storability. The molecular chaperone OsCPN10a enhances rice seed storability by forming a trimeric chaperone complex with OsCPN20‐OsHSP60‐3B that attenuates abscisic acid signaling via direct interaction with OsPYL10‐OsABIL1, thereby maintaining starch integrity and offering a promising target ...
Sufeng Liao +13 more
wiley +1 more source
Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity. [PDF]
J Chem Inf Model, 2022 Challa AP +9 more
europepmc +1 more source
New Phytologist, Volume 251, Issue 1, Page 207-227, July 2026.Network of VAMP714‐dependent interactions during salt stress. Summary Plant responses to salt stress include an altered root architecture mediated by ion imbalances, reactive oxygen species (ROS) accumulation, and altered hormonal responses. Auxin is implicated in these processes.
Jialei Sun +3 more
wiley +1 more source