Results 211 to 220 of about 1,516,213 (305)

Turn-engineering tunes the conformational rigidity of β-hairpin AMPs in achieving membrane selectivity and killing drug-resistant ESKAPE pathogens. [PDF]

Chem Sci
Lahiri P, Priyadarshini S, Saini M, Agrawal M, Mohid SA, Rajmani RS, Ammineni VSM, Biswas P, Asok A, Baidya AK, Bhunia A, Reddy G, Pathania R, Chatterjee J.   +13 more
europepmc   +1 more source

Tryptophan zippers: Stable, monomeric β-hairpins

, 2001
Andrea G. Cochran, Nicholas J. Skelton, Melissa A. Starovasnik   +2 more
openalex   +1 more source

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao, Jing Zhou, Jing Wang, Si‐Nan Zhao, Zhan‐Sheng Zhao, Qian Wang, Ya‐Nan Xie, Wei Jiao   +7 more
wiley   +1 more source

Structure-Function Relationship of the β-Hairpin of <i>Thermus thermophilus</i> HB27 Laccase. [PDF]

Int J Mol Sci
Miranda-Zaragoza B, Huerta-Miranda GA, García-García WI, Hernández-Álvarez E, Solano-Peralta A, Lee J, Strynadka N, Miranda-Hernández M, Rodríguez-Almazán C.   +8 more
europepmc   +1 more source

Circ_0006174 Drives Triple Negative Breast Cancer Progression and Immune Escape Through Regulating miR‐3139/PD‐L1 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) is characterized as an aggressive malignancy with limited therapeutic options. The circular RNA circ_0006174 has been implicated in oncogenic processes across various cancers; however, its specific role in the pathogenesis of TNBC remains unclear.
Yong‐Zhe Tang, Li Yang, Ling Wang, Xiao‐Qing Zhang, Jie Wang   +4 more
wiley   +1 more source

Complex and Non-sequential Current Signatures of a β-Hairpin Peptide Confined in a Nanopore. [PDF]

Anal Chem
Yamaji M, Chinappi M, Morozzo Della Rocca B, Usui K, Kawano R.   +4 more
europepmc   +1 more source

Tissue Factor Derived Β-Hairpin Peptides that Bind and Inhibit Fvii Activity

Menotti Ruvo, Angela Oliver, Emanuela Iaccarino, Antonella Migliorini, Samuele Di Cristofano, Lucia Falcigno, Gabriella D’Auria, Monica Cantile, Raffaele Ronca, Riccardo Sanna, Domenico Raimondo, Annamaria Sandomenico   +11 more
openalex   +1 more source

The role of a β‐bulge in the folding of the β‐hairpin structure in ubiquitin [PDF]

, 2001
Rita P.‐Y. Chen, B.G. Gopalacushina, Chien‐Chih Yang, Nei‐Li Chan, Philip A. Evans   +4 more
openalex   +1 more source

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source

Controlling Megasynthetase Module-Module Interactions through β-Hairpin Docking Domain Engineering. [PDF]

ACS Chem Biol
Rankin MR, Contreras KL, Gerwick WH, Gerwick L, Smith JL.   +4 more
europepmc   +1 more source