Results 291 to 300 of about 1,516,213 (305)

Stabilized β-Hairpin Peptide Inhibits Insulin Degrading Enzyme.

Journal of Medicinal Chemistry, 2018
Insulin-degrading enzyme (IDE) plays a critical role in both the proteolytic degradation and inactivation of insulin. The exploration of novel IDE inhibitors could aid in the study of novel therapeutics for type-2 diabetes.
Dan Yang, Weirong Qin, Xiaodong Shi, Bili Zhu, Mingsheng Xie, Hui Zhao, Bin Teng, Yujie Wu, Rongtong Zhao, Feng Yin, Peigen Ren, Lizhong Liu, Zigang Li   +12 more
semanticscholar   +1 more source

Comparative in vitro study on cytotoxicity of recombinant β‐hairpin peptides

Chemical Biology and Drug Design, 2018
D. Kuzmin, A. Emelianova, M. B. Kalashnikova, P. Panteleev, S. V. Balandin, E. Serebrovskaya, O. Belogurova-Ovchinnikova, T. Ovchinnikova   +7 more
semanticscholar   +1 more source

Effects of different force fields on the structural character of α synuclein β-hairpin peptide (35–56) in aqueous environment

Journal of Biomolecular Structure and Dynamics, 2018
Sangeeta Kundu
semanticscholar   +1 more source

A Therapeutic Potential of Animal β-hairpin Antimicrobial Peptides.

Current Medicinal Chemistry, 2017
P. Panteleev, S. V. Balandin, V. Ivanov, T. Ovchinnikova   +3 more
semanticscholar   +1 more source

A test of AMBER force fields in predicting the secondary structure of α-helical and β-hairpin peptides

, 2017
Ya Gao, Chaomin Zhang, Xianwei Wang, T. Zhu   +3 more
semanticscholar   +1 more source

An Updated Test of AMBER Force Fields and Implicit Solvent Models in Predicting the Secondary Structure of Helical, β-Hairpin, and Intrinsically Disordered Peptides.

Journal of Chemical Theory and Computation, 2016
I. Maffucci, A. Contini
semanticscholar   +1 more source

Structure-Activity Studies of β-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.

Journal of Molecular Biology, 2016
Geqing Wang, N. Drinkwater, D. Drew, C. Macraild, D. Chalmers, B. Mohanty, S. Lim, R. Anders, J. Beeson, P. Thompson, S. McGowan, J. Simpson, R. Norton, M. Scanlon   +13 more
semanticscholar   +1 more source

Gas-Phase Folding of a Prototypical Protonated Pentapeptide: Spectroscopic Evidence for Formation of a Charge-Stabilized β-Hairpin.

Journal of the American Chemical Society, 2016
Nicole L. Burke, Andrew F. DeBlase, James G. Redwine, J. Hopkins, S. A. McLuckey, T. Zwier   +5 more
semanticscholar   +1 more source

Inhibition of β-Amyloid Aggregation through a Designed β-Hairpin Peptide.

Langmuir, 2018
A. Jha, Mothukuri Ganesh Kumar, H. Gopi, K. Paknikar   +3 more
semanticscholar   +1 more source

Short, multiple-stranded β-hairpin peptides have antimicrobial potency with high selectivity and salt resistance.

Acta Biomaterialia, 2016
Shuli Chou, Changxuan Shao, Jiajun Wang, A. Shan, Lin Xu, N. Dong, Zhongyu Li   +6 more
semanticscholar   +1 more source