Results 131 to 140 of about 23,839 (210)

LK-1: an investigational therapy targeting hCG-β in metastatic breast, bladder, ovarian, and cervical cancers

open access: yesScientific Reports
Human chorionic gonadotropin beta (hCG-β), while primarily recognized for its role in pregnancy, has also been implicated in poor prognosis for cancer patients over the past several decades.
J. Helena Kinion   +3 more
doaj   +1 more source

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He   +18 more
wiley   +1 more source

Giant Mediastinal Teratoma in a Child: A Case Report With a Brief Review of the Literature

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
Contrast‐enhanced axial chest CT showing a large, well‐circumscribed mediastinal mass measuring approximately 15.9 × 14.1 cm (maximum axial dimensions). The lesion is predominantly of fluid attenuation, occupies nearly the entire left hemithorax, and produces marked rightward deviation of the mediastinum, compression of the contralateral lung ...
Urías Hernandez Lopez   +5 more
wiley   +1 more source

Investigating the Association Between Serum 25‐Hydroxyvitamin D (25(OH)D) and Body Mass Index (BMI) With In Vitro Fertilization (IVF) Outcomes Among Iranian Women: A Case‐Control Study

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Infertility affects approximately 18.3% of couples in Iran, and in vitro fertilization (IVF) remains a widely used treatment. Vitamin D deficiency and elevated body mass index (BMI) have been linked to poorer reproductive outcomes in some populations, but region‐specific evidence among Iranian women is limited.
Atefeh Asgari   +4 more
wiley   +1 more source

Diagnosis and management of ectopic pregnancy [PDF]

open access: yes, 2011
Duncan, W Colin   +4 more
core   +1 more source

In Two Patients with Economic and Social Issues Stage I Giant Seminoma [PDF]

open access: yes, 2013
The first case was in a 39-year-old man who complained of painless, left hemiscrotal swelling. The patient's serum β human chorionic gonadotropin (β-hCG) was elevated.
中島, 耕一   +7 more
core  

Sonographic Predictors and Long‐Term Reproductive Outcomes in Recurrent Cesarean Scar Pregnancy

open access: yesJournal of Ultrasound in Medicine, Volume 45, Issue 5, Page 1059-1068, May 2026.
Objectives To explore the ultrasound findings, treatment strategies, and reproductive outcomes in patients with recurrent cesarean scar pregnancy (CSP), providing evidence for clinical management. Methods We identified 1371 confirmed CSP from 1517 initially screened cases (2012–2022) through blinded image review. From 159 subsequent live births in this
Jianan Shi   +6 more
wiley   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

open access: yesAndrology, Volume 14, Issue 4, Page 1017-1028, May 2026.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

open access: yesAndrology, Volume 14, Issue 4, Page 978-991, May 2026.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre   +5 more
wiley   +1 more source

Pharmacogenetics of follicle‐stimulating hormone action in the male

open access: yesAndrology, Volume 14, Issue 4, Page 1064-1072, May 2026.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani   +7 more
wiley   +1 more source

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