Results 131 to 140 of about 899,318 (275)
BiologyExamining the relationship between an animal’s diet and physiology is crucial to understanding their responses to environmental change. Dietary-induced physiological variation can influence key life history processes, including growth and reproduction ...
Rebecca S. Lipscombe +3 more
doaj +1 more source
Ketogenic Diet and β-Hydroxybutyrate Suppress Bladder Cancer Growth and Enhance Anti-PD-L1 Immunotherapy Efficacy. [PDF]
Cancer SciKetogenic diet and β‐hydroxybutyrate (β‐HB) suppress bladder cancer growth through direct anti‐tumor mechanisms and enhance anti‐PD‐L1 immunotherapy efficacy. β‐HB upregulates PD‐L1 via JAK2‐STAT3 activation and remodels the tumor immune microenvironment, sensitizing tumors to immune checkpoint blockade. ABSTRACT The limited clinical efficacy of immune
Zeng Y +6 more
europepmc +2 more sources
Serum carnitine, β-hydroxybutyrate and ammonia levels during valproic acid therapy
, 1995 This study was performed in order to determine the effects of valproic acid on serum free carnitine, β-hydroxybutyrate and blood ammonia. Serum free carnitine, β-hydroxybutyrate and blood ammonia levels were measured in 24 epileptic children and in 24 ...
Hayri B. Toksoy +2 more
core +1 more source
Diabetic Medicine, EarlyView.Abstract Aims Managing diabetes during exercise remains challenging, particularly in settings of sustained physical activity such as diabetes‐camps. This study aimed to evaluate the efficacy and safety of a diabetes‐camp protocol including an adaptive algorithm for prandial bolus reduction and the use of automated insulin delivery (AID) exercise modes ...
Alzbeta Santova +12 more
wiley +1 more source
Indonesian Journal of Biotechnology, 2015 Poly-β-hydroxybutyrate (PHB) production from amylolytic Micrococcus sp. PG1. Poly-β-hydroxybutyrate(PHB) is an organic polymer, which synthesized by many bacteria and serves as internal energy.
Sebastian Margino +2 more
doaj
Hypoglycaemia care: Time to modernise our treatment standards
Diabetic Medicine, EarlyView.This editorial argues that hypoglycaemia self care should move beyond ‘any sugar will do’ and define what good recovery after treatment should involve. It proposes recovery‐focused standards using CGM metrics, such as time‐in‐range and repeat lows after treatment, alongside participant‐reported recovery, so existing and emerging approaches, including ...
David Russell‐Jones, Julia K. Mader
wiley +1 more source
Emerging insights into the role of BDH1 in the pathogenesis of human cancer
Frontiers in Oncologyβ-Hydroxybutyrate dehydrogenase 1 (BDH1) encodes a key enzyme in the metabolism of ketone bodies and plays a critical role in maintaining cellular energy homeostasis. As a member of the short-chain dehydrogenase/reductase (SDR) family, BDH1 catalyzes the
Penghui Wang +4 more
doaj +1 more source
Effect of co-substrate on production of poly-β- hydroxybutyrate (PHB) and copolymer PHBV from newly identified mutant Rhodobacter sphaeroides U7 cultivated under aerobic-dark condition [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2007 Photosynthetic bacterial mutant strain U7 was identified using both classical and molecular (16S rDNA) techniques to be Rhodobacter sphaeroides. The glutamate-acetate (GA) medium containing sodium acetate and sodium glutamate as carbon and nitrogen ...
Kemarajt Kemavongse +3 more
doaj
Effects of acetoacetate and d-β-hydroxybutyrate on bovine in vitro embryo development in serum-free medium [PDF]
, 2002 It is known that the ketone bodies acetoacetate and d-β-hydroxybutyrate can be metabolized by the early bovine embryo for in vitro development. In the present work, we report experiments leading to the culture of bovine embryos in the absence of serum ...
Facal, Nieves +6 more
core
Dapagliflozin Alters Plasma Metabolome in Patients With Type 1 Diabetes During Ketosis
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Use of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 1 diabetes (T1D) is limited by increased risk of ketoacidosis. We aimed to determine metabolic pathways affected by SGLT2i treatment in adults with T1D during ketosis induced by insulin withdrawal.
Rosa Yang +6 more
wiley +1 more source