Results 221 to 230 of about 899,318 (275)

GABA+‐Edited Magnetic Resonance Spectroscopy Deep Learning Quality Assessment Framework

Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1028-1041, September 2026.
ABSTRACT Purpose Motivated by the need to improve GABA+‐edited magnetic resonance spectroscopy (MRS) quality, we developed a three‐module framework to improve transient averaging based on quality. We hypothesized that training a deep learning (DL) model to differentiate spectrum quality could improve transient averaging compared to traditional ...
Hanna Bugler, Roberto Souza, Ashley D. Harris   +2 more
wiley   +1 more source

β-Hydroxybutyrate attenuates glycation-induced structural destabilization and amyloidogenic aggregation in human serum albumin. [PDF]

Biochem Biophys Rep
Mohammadnia H, Bohlooli M, Ghaffari-Moghaddam M, Khajeh M, Taghavi F.   +4 more
europepmc   +1 more source

Effects of Nano Zinc Oxide Supplementation on Oxidative Stress and Selected Metabolic Parameters During the Transition Period in Lacaune Ewes

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Nano zinc oxide supplementation did not significantly affect TOS, TAS or OSI in transition period Lacaune ewes. However, treatment related responses were observed for BHBA, phosphorus and total cholesterol, suggesting limited metabolic effects that require cautious interpretation.
Gaye Bulut, Neşe Hayat Aksoy, Caner Ozturk   +2 more
wiley   +1 more source

Effects of Oral Single-Dose Empagliflozin on Urinary Glucose, Serum β-Hydroxybutyrate, and Plasma Empagliflozin Concentrations in Healthy Adult Dogs. [PDF]

J Vet Pharmacol Ther
Plá Gutierrez AD, O'Sullivan ML, Côté E, McConkey S, KuKanich B, Martinez SE.   +5 more
europepmc   +1 more source

Conditional eIF2A Deletion Suggests Extra‐Adipose Mechanisms Underlying Metabolic Syndrome in Total‐Body eIF2A Knockout Mice

FASEB BioAdvances, Volume 8, Issue 9, September 2026.
Adipose tissue‐specific deficiency of eIF2A is insufficient to reproduce the metabolic defects observed in total‐body eIF2A knockout mice, suggesting that the systemic metabolic effects observed in these mice may arise from coordinated functions across multiple organs.
Adedeji Isaac Adeloye, Richard Anderson, Anchal Agarwal, Barsanjit Mazumder, Taras Y. Nazarko, Atefeh Bagheri, Archana Prabahar, Peng Jiang, Frank Tedeschi, William C. Merrick, David A. Buchner, Maria Hatzoglou, Roman V. Kondratov, Anton A. Komar   +13 more
wiley   +1 more source

β-Hydroxybutyrate Improves Glucose Metabolism in Streptozotocin-Induced Type 1 Diabetes by Inhibiting Gut and Liver Glucose Transporters via GPR109A. [PDF]

Diabetes
Li S, Wang J, Xin C, Dong Y, Xie A, Song J, Wan J, Yin J.   +7 more
europepmc   +1 more source

Stakeholders' perspectives on integrating point‐of‐care diagnostics into forensic death investigations in South Africa

Journal of Forensic Sciences, Volume 71, Issue 5, Page 2182-2192, September 2026.
Abstract Unnatural and unexplained deaths present critical challenges to the criminal justice, medico‐legal, and public health systems. This study explored forensic professionals' perspectives on the integration of point‐of‐care (POC) diagnostics into unnatural death investigations in South Africa.
Sebueng Ramatsokotla, Bathabile Soul, Kuhlula Maluleke, Lucinda Evert, Stefan Jansen van Vurren, Bettina Chale‐Matsau, Susan Mabotja, Evans Duah, Tivani Mashamba‐Thompson   +8 more
wiley   +1 more source

Intermittent Fasting Enhances Genome Integrity and Cytoprotective Pathways via (BHB) β-Hydroxybutyrate Signaling and Chromatin Remodeling. [PDF]

FASEB J
Parnas H, Bartman J, Rosenberg T, Yosofov R, Gabsi N, Marco A.   +5 more
europepmc   +1 more source

β-Hydroxybutyrate Modulates Metabolic Signaling and Partially Restores Peripheral Circadian Rhythms in High-Fat Diet-Fed Mice. [PDF]

Foods
Avital-Cohen N, Chapnik N, Froy O.
europepmc   +1 more source

Angiopoietin‐like protein 3 complete and partial deficiency markedly accelerates apolipoprotein B48 and B100 metabolism in triglyceride‐rich lipoproteins in humans

Journal of Internal Medicine, Volume 300, Issue 3, Page 312-328, September 2026.
Abstract Background Angiopoietin‐like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be explored in individuals with inherited loss‐of‐function (LOF) variants, who show reduced lifetime risk of atherosclerotic ...
Marcello Arca, Elias Björnson, Laura D'Erasmo, Alessia Di Costanzo, Simone Bini, Ilenia Minicocci, Daniele Tramontano, Stella Covino, Giuseppe Ciarlo, Manuela Lombardi, Sanni Söderlund, Niina Matikainen, Linda Andersson, Martin Adiels, Marja‐Riitta Taskinen, Chris J. Packard, Jan Borén   +16 more
wiley   +1 more source