Results 191 to 200 of about 56,729 (249)

β-Lactam concentrations monitored in the early phase of community-acquired sepsis in the intensive care unit. [PDF]

J Antimicrob Chemother
Liljedahl Prytz K, Kryss E, Oxelbark J, Källman J, Nilsson KF, Sundqvist M, Savilampi J.   +6 more
europepmc   +1 more source

Evaluation of a Product Intended for Microbiological Control in Animal Production, and Its Combination With Halquinol

Animal Research and One Health, Volume 4, Issue 3, Page 302-313, August 2026.
Activo Liquid and Halquinol inhibit Salmonella and Escherichia coli in culture media. Activo Liquid exhibits bactericidal action, whereas HA is bacteriostatic, and their combination results in positive or indifferent interactions. This combination effectively inhibits E. coli throughout digestion simulation, thus reducing the required concentrations of
Alberto Gonçalves Evangelista, Lucas dos Santos Janotto, Adriana Paula Possamai, Carolina Cini Perry, Francine Lemes Ribeiro, Rafael Canonenco de Araujo, Fernando Bittencourt Luciano   +6 more
wiley   +1 more source

Matrine Restores Porcine-Origin β-Lactam-Resistant <i>Escherichia coli</i> to Cefepime and Cefquinome: Association with Impaired Biofilm Formation and β-Lactamase Production. [PDF]

Antibiotics (Basel)
Yang B, Yang W, Hu B, Zhao J, Deng H, Yi L, Jian P, Hong Z, Yu D.   +8 more
europepmc   +1 more source

Successful Rapid Desensitization to Ceftazidime/Avibactam in a Patient With Cystic Fibrosis and Multidrug‐Resistant Pseudomonas aeruginosa Pneumonia: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Ceftazidime/avibactam (CAZ‐AVI) is an important therapeutic option for multidrug‐resistant (MDR) Pseudomonas aeruginosa infections; however, hypersensitivity reactions may preclude its use and create significant therapeutic challenges. We report a 21‐year‐old woman with cystic fibrosis and recurrent MDR P.
Zuoren Zhou, Jinqi Zhu, Ge Wu, Xi Kang, Qing Wang, Jie Liu, Yan Jiang   +6 more
wiley   +1 more source

Global response to antibiotic exposure reveals a critical role for nucleotide metabolism in high-level β-lactam tolerance. [PDF]

NPJ Antimicrob Resist
Keller MR, Kazi MI, Saleh A, Basu U, Shin JH, Rhee K, Dörr T.   +6 more
europepmc   +1 more source

Combination of Oral Doxycycline and Rifampin for Pan‐Drug Resistant Klebsiella pneumoniae Infection: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Pan‐drug resistant Klebsiella pneumoniae is a major therapeutic challenge, particularly when standard last‐line agents are unavailable or contraindicated. We report a 45‐year‐old man with multifocal osteomyelitis and persistent purulent wound discharge despite broad‐spectrum antibiotics, repeated debridement, and two sequential amputations ...
Ali Akbar Heydari, Sepideh Elyasi, Farshad Abedi   +2 more
wiley   +1 more source

The Visual Predictive Check and Real‐World Data

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 394-398, August 2026.
The visual predictive check (VPC) is a standard tool for assessing pharmacometric model suitability, producing visualizations that compare observed data with simulated data such that both model structure and model variability terms can be assessed. However, real‐world data commonly reflect clinical decision‐making that adapts therapy in response to ...
Jasmine H. Hughes, Martin Bergstrand, Ron J. Keizer   +2 more
wiley   +1 more source

An enzymatic microfluidic sensor for β-lactam antibiotics based on cross-linked ancestral β-lactamase crystals. [PDF]

Nanoscale Adv
Rodríguez-Ruiz I, Moya-Garrido P, Risso VA, Martínez-Rodríguez S, Teychené S, Sanchez-Ruiz JM, Gavira JA.   +6 more
europepmc   +1 more source

Two Novel 1,4‐Naphthoquinone Derivatives as Potent Agents Against Multidrug‐Resistant Staphylococcus aureus and Pathogenic Gram‐Positive Bacteria

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Drug‐resistant bacteria such as Methicillin‐resistant Staphylococcus aureus (MRSA) and Quinolone‐resistant S. aureus (QRSA), are a growing problem, creating a need for the development of novel antimicrobial agents. In this study, we designed and synthesized two novel 1,4‐naphthoquinone derivatives, LHN‐1034 and LHN‐1035, and evaluated their ...
HyunChan Song, Haena Lee, Ji‐Hyun Yoon, Hyunkyung Choi, Hakwon Kim, Ki‐Young Kim   +5 more
wiley   +1 more source