Results 101 to 110 of about 872,130 (197)
Prevalence of thalassaemia among childbearing-age Li and Han populations in Hainan Province
HematologyObjectives Accurate epidemiological data are crucial for effective disease prevention and treatment. We conducted a large-scale survey to explore the thalassaemia prevalence and spectrum among the two major ethnic groups in Hainan Province.Methods A ...
Fangchao Tao +8 more
doaj +1 more source
Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde +2 more
wiley +1 more source
β+-thalassaemia in the Po river delta region (northern Italy): Genotype and β globin synthesis
, 1985 Six β+-thalassaemic patients from the Po river delta region have been studied. Using synthetic oligonucleotides as specific hybridisation probes, the β+ IVS I mutation (G→A at position 108) was demonstrated.
BUZZONI D +9 more
core +1 more source
Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing
Advanced Science, Volume 13, Issue 50, 7 September 2026.A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo +11 more
wiley +1 more source
, 1973 Summary. Eleven children who are double heterozygotes for β‐ and δβ‐thalassaemia are described. Of their parents one was always heterozygous for β‐(A2) thalassaemia (increased Hb A2), and the other for the high F variant or δβ‐thalassaemia (increased Hb ...
Kattamis, C. +4 more
core +1 more source
Molecular, haematological and clinical studies of the silent β-thalassaemia in Greece
, 2002 We investigated the genetic defects underlying the phenotype of “silent” β-thalassaemia in the Greek population and the clinical, haematological, biosynthetic and molecular data in 33 β-thalassaemia intermedia patients, double heterozygotes for classic ...
Maragoudaki, Eleni +1 more
core +1 more source
Therapeutic Silencing of Tmprss6 Reduces Iron‐Induced Inflammation and Prolongs Survival in MDS Mice
American Journal of Hematology, Volume 101, Issue 9, Page 2105-2122, September 2026.ABSTRACT Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic disorders characterized by ineffective hematopoiesis, cytopenias, and an increased risk of progression to acute myeloid leukemia (AML). Despite advances in supportive and targeted therapies, disease‐modifying interventions remain limited.
Shahla Vilcassim +13 more
wiley +1 more source
Exploration of antenatal β-thalassaemia carrier screening in Victoria, Australia
, 2012 Publication included in thesis:Cousens, N. E., Gaff, C. L., Metcalfe, S. A. & Delatycki, M. B. (2010). Carrier screening for Beta-thalassaemia: a review of international practice. European Journal of Human Genetics, 18(10), 1077-1083.
Cousens, Nicole Elizabeth
core +1 more source
Myoglobin in homozygous β thalassaemia
, 1974 Purified, haemoglobin free oxymyoglobin preparations, obtained from heart tissue of adult subjects (Mb A) were compared with myoglobin obtained from heart tissue of fetuses (Mb F) and of individuals with homozygous β thalassaemia (Mb C).
Kalos, A. +2 more
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