Results 131 to 140 of about 872,130 (197)

Cerebral Blood Transit in Sickle Cell Anemia

Journal of Magnetic Resonance Imaging, Volume 64, Issue 3, Page 738-750, September 2026.
ABSTRACT Background Sickle cell anemia (SCA) patients upregulate cerebral blood flow to compensate for decreased arterial oxygen content. Such hyperemic conditions can manifest as venous hyperintense signal on arterial spin labeling (ASL) MRI, which may reflect faster capillary blood transit, altered oxygen extraction fraction (OEF), and infarct risk ...
Wesley T. Richerson, Megan A. Aumann, Alexander K. Song, Samantha Davis, Lauren Milner, Maria Garza, Dann Martin, L. Taylor Davis, Sumit Pruthi, Lori C. Jordan, Manus J. Donahue   +10 more
wiley   +1 more source

Extramedullary haematopoiesis in patients with transfusion dependent β-thalassaemia (TDT): a systematic review. [PDF]

Ann Med, 2022
A Subahi E, Ata F, Choudry H, Iqbal P, A AlHiyari M, T Soliman A, De Sanctis V, A Yassin M.   +7 more
europepmc   +1 more source

Smart Design: Integrating Artificial Intelligence and Gene Editing for Advanced mRNA Therapeutics

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The challenges of mRNA therapy and the application of artificial intelligence and gene editing in the field of mRNA drugs. ABSTRACT Artificial intelligence (AI) and gene editing are increasingly being applied to the design and evaluation of mRNA therapeutics.
Haixing Shi, Shengbin Liu, Danni Dai, Shanhui Jiang, Tingchen Tian, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Fang Liu, Xue Tang, Xin Jiang, Xiangrong Song   +11 more
wiley   +1 more source

Extramedullary haematopoiesis presenting as an adnexal mass in a patient with β-thalassaemia. [PDF]

BMJ Case Rep, 2022
Filippi V, Reina H, Monod C, Manegold-Brauer G.   +3 more
europepmc   +1 more source

Association of heterocellular HPFH, β+-thalassaemia, and δβ° -thallassaemia: Haematological and molecular aspects

, 1984
An Italian family in which heterocellular hereditary persistence of fetal haemoglobin (HPFH) interacts with both β+- and δβ-thalassaemia is described.
Care A., Giampaolo A., Marinucci M., Massa A., Cianetti L., Mavilio F., Ceccanti M., Sposi N. M., Petrini M., Calandrini M.   +9 more
core  

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

MedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu, Yuqin Jin, Baochao Li, Jie Deng, Yiwen Zhou, Jinglun Zhang, Huang Li   +6 more
wiley   +1 more source

Hepcidin Levels in Multi Transfused β Thalassemia Major Patients

Journal of Rawalpindi Medical College, 2016
Background: To determine and compare the serum hepcidin levels and conventional markers of iron status in patients of β- thalassaemia major with controls.
Muhammad Jawad
doaj  

A systematic review on thalassaemia screening and birth reduction initiatives cost to success [PDF]

Introduction: Thalassaemia has been prevalent with high morbidity and mortality rates since 1925. Although there is a lack of systematic review on the costs of prevention that has yielded reductions in thalassaemia prevalence, this review will show a ...
Abd Rahim, Azrin Syahida, Abd. Rahim, Nour El Huda, Jaafar, Safurah   +2 more
core  

Mirror Syndrome (Ballantyne Syndrome): Prenatal Diagnosis, Pathophysiology, and the Role of Fetal Therapy—A Narrative Review

Prenatal Diagnosis, Volume 46, Issue 10, Page 1617-1625, September 2026.
ABSTRACT Mirror syndrome is a rare maternal–fetal condition associated with fetal hydrops and a high risk of adverse maternal and fetal perinatal outcomes. Its diagnosis is challenging due to the lack of standardized diagnostic criteria and its clinical and biochemical overlap with preeclampsia.
Riccardo Tudisco, Pauline Latapie, Anita Romiti, Alexandra Benachi, Maelig Abgral, Alexandre J. Vivanti   +5 more
wiley   +1 more source

Impaired neutrophil extracellular trap formation in β-thalassaemia/HbE. [PDF]

Sci Rep, 2022
Thubthed R, Siriworadetkun S, Paiboonsukwong K, Fucharoen S, Pattanapanyasat K, Vadolas J, Svasti S, Chaichompoo P.   +7 more
europepmc   +1 more source