Results 141 to 150 of about 872,130 (197)

Hydroxyurea (hydroxycarbamide) use in adults with haemoglobin SC disease: A real‐world study in Quebec

British Journal of Haematology, Volume 209, Issue 3, Page 1291-1300, September 2026.
Summary Haemoglobin SC (HbSC) disease is the second most prevalent form of sickle cell disease, but evidence for hydroxyurea (hydroxycarbamide; HU) to prevent pain episodes was limited until the prospective identification of variables as outcomes for treatment (PIVOT) trial.
Alice Girard, Laurianne Charette, Mélissa Haouchine, Laurence Bozec, Mohamed Zakaria Bachir Bouyadjera, Mariane Poitras, Vincent‐Thierry Taillefer, Chloé Trudeau, Yves Pastore, Nathalie Letarte, Stéphanie Forté   +10 more
wiley   +1 more source

Hematopoietic stem cell transplantation for people with β-thalassaemia. [PDF]

Cochrane Database Syst Rev, 2021
Sharma A, Jagannath VA, Puri L.
europepmc   +1 more source

Posaconazole Target Attainment in Critically Ill Children: A 15‐Year Single‐Center Retrospective Analysis

Clinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Posaconazole is a triazole antifungal agent used for prophylaxis and treatment of invasive fungal diseases. Posaconazole has high inter‐individual variability in dose‐exposure relationship and benefits from therapeutic drug monitoring (TDM). Adult studies report particularly high rates of subtherapeutic exposure among intensive care unit (ICU)
Kathryn Pavia, Addison Pritchett, Jennifer Goldman   +2 more
wiley   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, Volume 293, Issue 17, Page 5149-5169, September 2026.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

Socio-economic disparities in clinical outcomes of transfusion-dependent β-thalassaemia patients. [PDF]

J Health Popul Nutr
Avraam D, Angastiniotis M, Soteriades ES, Eleftheriou A.   +3 more
europepmc   +1 more source

A prospective guide for clinical implementation of selected OGTT- derived surrogate indices for the evaluation of β- cell function and insulin sensitivity in patients with transfusion-dependent β- thalassaemia. [PDF]

Acta Biomed, 2023
De Sanctis V, Soliman AT, Daar S, Tzoulis P, Karimi M, Saki F, Di Maio S, Kattamis C.   +7 more
europepmc   +1 more source

Leg Ulcers in Thalassaemia: A Comparative Retrospective Review of Transfusion‐Dependent and Non‐Transfusion‐Dependent Patients

International Wound Journal, Volume 23, Issue 9, September 2026.
ABSTRACT To compare clinical and laboratory characteristics of transfusion‐dependent and non‐transfusion‐dependent beta thalassaemia patients with leg ulcers, and to identify contributing and protective factors We retrospectively reviewed 12 patients with beta thalassaemia and leg ulcers (seven transfusion‐dependent and five non‐transfusion‐dependent ...
Sacha El Khoury, Nicole Charbel, Farouk Kabbara, Joseph Klim, Ghida Ismail, Farah Ismail, Suzanne Koussa, Ali Taher   +7 more
wiley   +1 more source

Neutrophil extracellular traps induced by activated platelets as a cause of neutrophil-platelet aggregation in β-thalassaemia/haemoglobin E patients. [PDF]

Br J Haematol
Thubthed R, Praneetponkang R, Sittipaisankul P, Thiengtavor C, Chumpuchanaphai S, Paiboonsukwong K, Fucharoen S, Pattanapanyasat K, Vadolas J, Smith DR, Svasti S, Chaichompoo P.   +11 more
europepmc   +1 more source

Hemoglobin Lepore‐Boston‐Washington: A Rare Cause of Unmeasurable HbA1c and Diagnostic Challenge in Diabetes

Journal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
Filippo Russo, Silvia Trombetti, Maria Rosaria Storino, Raffaele Sessa, Carmela De Felice, Giuseppe Schiavone, Michela Grosso   +6 more
wiley   +1 more source

Polynucleotides HPT‐Based Dermal Filler for Skin Rejuvenation: A Prospective Clinical Investigation

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Polynucleotides (PN)‐based dermal fillers are increasingly used for skin rejuvenation due to their biocompatibility and regenerative properties. Aims This study aimed to confirm the efficacy and safety of Plinest (Mastelli) in improving skin hydration of the face, neck, and décolleté over 4 months follow‐up.
Chiara Teramo, Andrea Mattioli, Carolina Prussia   +2 more
wiley   +1 more source