Results 21 to 30 of about 872,130 (197)

Haemoglobinopathies and β-Thalassaemia among the Tribals Working in the Tea Gardens of Assam, India [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Prevalence of haemoglobinopathies and β-thalassaemia are very high in India but information about its status among the tribals working in the tea gardens of Assam is very less.
Anju Barhai Teli, Rumi Deori, Sidhartha Protim Saikia   +2 more
doaj   +1 more source

Current and Future Therapies for β-Thalassaemia: A Review Article [PDF]

, 2021
This article will review recent and forthcoming advances in the treatment of thalassaemia. Prognosis of thalassaemia has dramatically improved in the last 50 years with the development of regular and safe blood transfusions and iron chelation.
Emanuele Angelucci, Livia Giannoni
core   +1 more source

The worldwide molecular spectrum and distribution of thalassaemia: a systematic review

Annals of Human Biology, 2021
Context Thalassaemia is one of the most common inherited autosomal recessive disorders around the world. A considerable amount of literature has been published about the type of mutations and the prevalence of thalassaemia, but findings are often ...
Mina Ebrahimi, Javad Mohammadi-Asl, Fakher Rahim   +2 more
doaj   +1 more source

Molecular and hematological studies in a cohort of beta zero South East Asia deletion (β°-thal SEA) from Malaysian perspective

Frontiers in Pediatrics, 2022
We report the haematological parameters and molecular characterization of beta zero (β°) South East Asia (SEA) deletion in the HBB gene cluster with unusually high levels of Hb F compared to a classical heterozygous beta zero (β°)-thalassaemia ...
Norafiza Mohd Yasin, Faidatul Syazlin Abdul Hamid, Syahzuwan Hassan, Aziee Sudin, Haiyuni Yassim, Ermi Neiza Mohd Sahid, Yuslina Mat Yusoff, Ezalia Esa, Mohamed Saleem   +8 more
doaj   +1 more source

Haemoglobinopathies: A Retrospective Study from a Tertiary Care Centre, Southern India [PDF]

National Journal of Laboratory Medicine, 2022
Introduction: Thalassaemia and other structural haemoglobinopathies are the major genetic disorders that cause significant morbidity in children. Haemoglobinopathies need to be diagnosed at the earliest in order to offer suitable treatment, carrier ...
Hemalata Lokanatha, Pradeep Rudramurthy
doaj   +1 more source

Increased autophagy leads to decreased apoptosis during β-thalassaemic mouse and patient erythropoiesis

Scientific Reports, 2022
β-Thalassaemia results from defects in β-globin chain production, leading to ineffective erythropoiesis and subsequently to severe anaemia and other complications.
Pornthip Chaichompoo, Ramaneeya Nithipongvanitch, Wasinee Kheansaard, Alisa Tubsuwan, Kanitta Srinoun, Jim Vadolas, Suthat Fucharoen, Duncan R. Smith, Pranee Winichagoon, Saovaros Svasti   +9 more
doaj   +1 more source

HbE β-Thalassaemia in Malaysia: revisited [PDF]

, 2013
HbE β – thalassaemia is a public health problem in Malaysia and the most common type of thalassaemia seen in the Malays. It shows considerable diverse phenotypes.
George, Elizabeth
core   +1 more source

Effect of α(+)-Thalassaemia on Episodes of Fever due to Malaria and Other Causes: A Community-Based Cohort Study in Tanzania. [PDF]

, 2011
It is controversial to what degree α(+)-thalassaemia protects against episodes of uncomplicated malaria and febrile disease due to infections other than Plasmodium. In Tanzania, in children aged 6-60 months and height-for-age z-score < -1.5 SD (n = 612),
Veenemans, J., Veenemans, Jacobien, Mbugi Erasto V, Huub FJ Savelkoul, Savelkoul, H.F.J., Demir, Ayşe Y, Savelkoul, Huub FJ, Hans Verhoef, Baidjoe, Amrish Y, Esther JS Jansen, Amrish Y Baidjoe, Kraaijenhagen, Rob J, Jansen Esther JS, Savelkoul, Huub F J, Veenemans Jacobien, Demir Ayşe Y, Mbugi, Erasto V, Rob J Kraaijenhagen, Savelkoul, H.F.J, Baidjoe, A.Y., Verhoef, H., Verhoef Hans, Kraaijenhagen Rob J, Erasto V Mbugi, Jansen, Esther JS, Savelkoul Huub FJ, Ayşe Y Demir, Baidjoe Amrish Y, Jansen, E.J.S., Mbugi, E.V., Jacobien Veenemans, Verhoef, Hans, Jansen, Esther J S, Demir, A.Y., Kraaijenhagen, R.J.   +34 more
core   +1 more source

A Novel Algorithm Using Cell Population Data (VCS Parameters) as a Screening Discriminant between Alpha and Beta Thalassemia Traits

Diagnostics, 2021
Thalassemia is one of the major inherited haematological disorders in the Southeast Asia region. This study explored the potential utility of red blood cell (RBC) parameters and reticulocyte cell population data (CPD) parameters in the differential ...
Angeli Ambayya, Santina Sahibon, Thoo Wei Yang, Qian-Yun Zhang, Rosline Hassan, Jameela Sathar   +5 more
doaj   +1 more source

Screening of thalassaemia carriers and its limitations [PDF]

, 2014
The α and β-thalassaemias (thal) are common genetic disorders of globin chain synthesis where the carriers have deficiency of α or β globin chain respectively.
George, Elizabeth
core   +1 more source