Results 91 to 100 of about 3,518,946 (289)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Σελίδες από την παιδεία της Πόλης / υπό Φ. Β. [PDF]

open access: yes, 1988
19 σ.+1 λ.; 17χ24 εκ.Το ιωβηλαίο των καθηγητών Γ. Ναρλή, Αλ. Αλεξανδρίδη και Β.
Β., Φ.
core  

Modified Non-Linear Triangular Neutrosophic Numbers: Theory and Applications in Integral Equation [PDF]

open access: yesNeutrosophic Sets and Systems
Existing methods for handling uncertainty and imprecision often fall short in addressing complex real-world problems. To overcome these limitations, this paper introduces a novel Generalized Non-Linear Triangular Neutrosophic Number (GNLTNN) that ...
Mohammed Shapique, E. Mathivadhana
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Morphological and chemical variations of sweet flag (Acorus calamus L.) in the Czech and Finnish gene bank collection

open access: yesHorticultural Science, 2007
The aim of this study was to analyze both the morphological and chemical characteristics of Acorus calamus plants collected from the natural sites in the Czech Republic and to compare them to the sweet flags growing in Finland, Slovenia and Canada, which
K. Dušek   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Synthesis of β-Haloketones by β-Addition Reactions of α,β-Unsaturated Ketones with BX3 (X=Br, Cl) as Halide Source

open access: yes, 2014
A series of β-bromoketones and β-chloroketones were synthesized by the addition reactions of α,β-unsaturated ketones under BX3 (X = Br, Cl) and ethylene glycol reaction system.
Lee, Adam Shih-Yuan; Wang, Shu-Huei; Chang, Yu-Ting
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Yeast growth selection system for the identification of cell-active inhibitors of [beta]-secretase [PDF]

open access: yes, 2004
The production and deposition of the cytotoxic Aβ peptide is a central event in the pathogenesis of Alzheimer’s disease (AD). Aβ is excised from the amyloid precursor protein (APP) through sequential actions of the β-secretase, which cleaves at the ...
Middendorp, Oliver M.
core   +1 more source

Home - About - Disclaimer - Privacy