Results 61 to 70 of about 2,502,780 (248)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Does Momentum Matter? Modeling Stock Returns through Fama-French and Carhart Model for Pakistan Stock Exchange

Business Review
Asset pricing models are widely applied for explaining variations in stock returns. The applicability of these models is tested on different markets for assessing different stock price anomalies.
Mirza Osama Bin Shahid , AbdurRahman Aleemi, Muhammad AsadUllah   +2 more
doaj   +1 more source

Effect of β-Glucan on cold-stress resistance of striped catfish, Pangasianodon hypophthalmus (Sauvage, 1878)

Veterinární Medicína, 2014
These experiments were performed to determine the effects of dietary β-glucan on stress responses of striped catfish (Pangasianodon hypophthalmus). Fish were fed for nine weeks with a diet containing 0 (control), 0.5% (G1), 1% (G2) and 2% (G3 group) β ...
S. Soltanian, M.N. Adloo, M. Hafeziyeh, N. Ghadimi   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The effect of elicitors on oleanolic acid accumulation and expression of triterpenoid synthesis genes in Gentiana straminea

Biologia Plantarum, 2013
Gentiana straminea is native to the Qinghai-Tibet plateau, where it is exposed to extremes of cold and strong UV-B radiation. Here we showed that low temperature, but not UV-B radiation, affected the accumulation of the triterpenoid oleanolic acid ...
Z. -J. Zhao, Y. -G. Song, Y. -L. Liu, M. Qiao, X. -L. Zhai, F. -N. Xiang   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Knockout mutants of Arabidopsis thaliana β-galactosidase. Modifications in the cell wall saccharides and enzymatic activities

Biologia Plantarum, 2018
This work studied the six β-galactosidases (BGALs) of the subfamily a1 of Arabidopsis, that have been proposed to play important roles in the cell wall remodelling during plant development, although their precise functions are still unknown.
M. Moneo-Sánchez, L. Izquierdo, I. Martín, J. Hernández-Nistal, L. Albornos, B. Dopico, E. Labrador   +6 more
doaj   +1 more source

Observation of the ψð3686ß decays into Σ+ Σ - ω and Σ+ Σ - φ

, 2023
Based on (2712.4 +/- 14.3) x 106 events recorded at the psi(3686) nominal mass collected with the BESIII detector operating at the BEPCII collider, the psi(3686) -> E +/- E over bar -omega and E +/- E over bar -phi decays are observed for the first time with statistical significances of 13.8 sigma and 7.6 sigma, respectively.
Ablikim, M., Adlarson, Patrik, Johansson, Tord, Kupsc, Andrzej, Schönning, Karin, Thoren, V., Wolke, Magnus, Zu, J.   +7 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Isolation and molecular characterization of pathogenesis related PR2 gene and its promoter from Brassica juncea

Biologia Plantarum, 2017
Pathogenesis-related (PR) proteins play key roles in plant disease resistance. Here, we isolated and characterized pathogenesis-related PR2 gene encoding β-1,3-glucanase from Brassica juncea and named it BjPR2 (GenBank accession number DQ359125).
S. Ali, N. Chandrashekar, S. Rawat, N. M. C. Nayanakantha, Z. A. Mir, A. Manoharan, M. Sultana, A. Grover   +7 more
doaj   +1 more source