Results 101 to 110 of about 22,283 (171)

Pancreatic cancer cachexia promotes cardiac dysfunction through altered adrenergic signalling in the heart

The Journal of Physiology, Volume 604, Issue 15, Page 6281-6301, 1 August 2026.
Abstract figure legend The β1‐adrenergic receptor is the predominant adrenergic subtype expressed on cardiac myocytes. Upon stimulation it activates downstream signalling pathways that increase the heart rate and cardiac output to meet metabolic demands.
Parham Diba, Peter R. Levasseur, Samuel D. Newton, Khia Min Sabrina Koh, Paige C. Arneson‐Wissink, Xinxia Zhu, Peter Pham, Heike Mendez, Luke Whitcomb, Ariana Sattler, William R Woodward, Beth A. Habecker, Daniel L. Marks, Aaron J. Grossberg   +13 more
wiley   +1 more source

CRISPR-CasRx-mediated disruption of Aqp1/Adrb2/Rock1/Rock2 genes reduces intraocular pressure and retinal ganglion cell damage in mice

Nature Communications
Glaucoma affects approximately 80 million individuals worldwide, a condition for which current treatment options are inadequate. The primary risk factor for glaucoma is elevated intraocular pressure.
Mingyu Yao, Zhenhai Zeng, Siheng Li, Zhilin Zou, Zhongxing Chen, Xinyi Chen, Qingyi Gao, Guoli Zhao, Aodong Chen, Zheng Li, Yiran Wang, Rui Ning, Colm McAlinden, Xingtao Zhou, Jinhai Huang   +14 more
doaj   +1 more source

From protection to predisposition: A narrative review of sex‐specific vascular responses to acute stressors across the lifespan

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality, with females exhibiting relative biological protection against CVD compared to males through hormonal and nonhormonal mechanisms—a protection that diminishes with age. While previous research has identified early risk factors in CVD pathogenesis, the physiological
Mya Lax, Jennifer S. Williams
wiley   +1 more source

Overactivation of Norepinephrine-β2-Adrenergic Receptor Axis Promotes Corneal Neovascularization. [PDF]

Invest Ophthalmol Vis Sci, 2023
Dong Q, Qi B, Zhang B, Zhuang X, Chen S, Zhou Q, Zhang BN, Li S.   +7 more
europepmc   +1 more source

Activation of β2-Adrenergic Receptor Alleviates Viral Myocarditis by Regulating Energy Metabolism in Monocyte-derived Macrophages via the AMPK Pathway. [PDF]

Inflammation
Li QL, Guo YX, Li JF, Xie HB, Qian J, Wu WF.   +5 more
europepmc   +1 more source

Myeloid cell-specific β2-adrenergic receptor deletion improves early cardiac injury resolution via de-repression of Anxa1. [PDF]

Theranostics
Nayak TK, Bajpai A, Patwa V, Carter RL, Enjamuri N, Gao E, Rajan S, Xiang YK, Tilley DG.   +8 more
europepmc   +1 more source

Nebivolol prevents exhausted T cells and enhances cytotoxicity against MCF-7 breast cancer cells in a β2-adrenergic receptor-dependent manner. [PDF]

Clin Exp Immunol
Hajiaghayi M, Gholizadeh F, Rahbari N, Emamnia N, Shih SCC, Darlington PJ.   +5 more
europepmc   +1 more source

Efficacy of β2-adrenergic receptor agonist combined with corticosteroid in the treatment of children with cough variant asthma. [PDF]

World J Clin Cases, 2023
Cao JY, Wang YC, Deng XX.
europepmc   +1 more source

Unraveling the nexus in the neuro-neoplastic progression of colorectal cancer: Potential role of β2-adrenergic receptor (β2-AR). [PDF]

J Adv Res
Varghese E, Samuel SM, Hornak S, Kubatka P, Büsselberg D.   +4 more
europepmc   +1 more source

Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor. [PDF]

Nat Commun, 2023
Heng J, Hu Y, Pérez-Hernández G, Inoue A, Zhao J, Ma X, Sun X, Kawakami K, Ikuta T, Ding J, Yang Y, Zhang L, Peng S, Niu X, Li H, Guixà-González R, Jin C, Hildebrand PW, Chen C, Kobilka BK.   +19 more
europepmc   +1 more source