Results 131 to 140 of about 1,803,893 (333)
Frontiers in Immunology, 2020 Gamma delta (γδ) T cells kill transformed cells, and increased circulating γδ T cells levels correlate with improved outcome in cancer patients; however, their function within the breast tumor microenvironment (TME) remains controversial.
Gabrielle M. Siegers +6 more
doaj +1 more source
γδ T cells in homeostasis and host defence of epithelial barrier tissues
Nature reviews. Immunology, 2017 Epithelial surfaces line the body and provide a crucial interface between the body and the external environment. Tissue-resident epithelial γδ T cells represent a major T cell population in the epithelial tissues and are ideally positioned to carry out ...
M. M. Nielsen, D. Witherden, W. Havran
semanticscholar +1 more source
Human γδ T cells express PLZF.
, 2013 (A) The MFI of PLZF expression in γδ T cells as compared to CD3+CD56−CD161− T cells (P value is shown). Histogram shows PLZF expression in γδ T cells collected from two healthy donors in comparison to γδ T cells from the PLZF-deficient donor.
Bushra Zaidi (344959) +10 more
core +1 more source
Image_5_D-Mannose Suppresses γδ T Cells and Alleviates Murine Psoriasis.jpeg
, 2022 Psoriasis is a chronic skin disorder associated with multiple sequelae, such as psoriatic arthritis and cardiovascular diseases. Increasing evidence has shown that γδ T cells, as sources of IL-17A, play critical roles in psoriatic inflammations. However,
Yuhualei Pan (10096633) +7 more
core +1 more source
Advanced Materials Technologies, EarlyView.Hierarchical multi‐material TPMS lattices are engineered as flexible tactile sensors by combining soft and stiff elastomeric layers with a conformal conductive coating. The bilayer architecture delivers sensitivity at low pressures while maintaining a broad detectable range under large loads, enabling reliable pressure and vibration monitoring for ...
Reza Noroozi +3 more
wiley +1 more source
Microglia Induce Neurotoxic IL-17+ γδ T Cells Dependent on TLR2, TLR4, and TLR9 Activation.
PLoS ONE, 2015 BackgroundInterleukin-17 (IL-17) acts as a key regulator in central nervous system (CNS) inflammation. γδ T cells are an important innate source of IL-17. Both IL-17+ γδ T cells and microglia, the major resident immune cells of the brain, are involved in
Katja Derkow +3 more
doaj +1 more source
Image_3_D-Mannose Suppresses γδ T Cells and Alleviates Murine Psoriasis.tif
, 2022 Psoriasis is a chronic skin disorder associated with multiple sequelae, such as psoriatic arthritis and cardiovascular diseases. Increasing evidence has shown that γδ T cells, as sources of IL-17A, play critical roles in psoriatic inflammations. However,
Yuhualei Pan (10096633) +7 more
core +1 more source
Advanced Robotics Research, EarlyView.An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy +13 more
wiley +1 more source
Anti-Anisakis antibodies in colon cancer patients and their relationship with γδ T-cells
Many pathogens are related to carcinogenesis. Chronic infammation, as a result of persistent infection, leads to DNA damage, higher expression of oncogenes, decreased apoptosis and immunosuppression, which are some of the reasons for cancer induction ...
Hurtado-Marcos, Carolina +10 more
core +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source