Results 291 to 300 of about 1,803,893 (333)

The mechanism regulating the cytotoxicity of γδ T cells activated by mycobacterium tuberculosis heat-resistant antigen based on RNA-seq analysis. [PDF]

Front Immunol
Song Y, Guo F, Dai H, Zhou X, Dong S, Zhang H, Qian Z, Li B, Wang X, Xu T, Wang H.   +10 more
europepmc   +1 more source

TIM-3 and γδ T cells: new players in breast cancer dissemination. [PDF]

EMBO J
Galluzzi L, Galassi C, Wiest DL.
europepmc   +1 more source

Bacterial suppression of intestinal fungi via activation of human gut γδ T-cells

Mathew L, Carlson S, Savage M, Pardieu C, O’Brien M, Crawley E, Harrow P, Kaune A, Devlin E, Priest EL, Crescente M, Martinod K, Boot J, Gasparetto M, Kok K, Lindsay JO, Richardson JP, Naglik JR, Stagg AJ, Eberl M, Sze SK, Munro CA, McCarthy NE.   +22 more
europepmc   +1 more source

Crosstalk between γδ T cells and the microbiota

Nature Microbiology, 2021
The role of the microbiota in the development and function of γδ T cells-a T cell subset characterized by a T cell receptor composed of one γ-chain and one δ-chain-has been investigated in multiple organs in mice and humans.
P. Papotto, B. Yilmaz, B. Silva‐Santos
semanticscholar   +2 more sources

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Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge

Nature Reviews Immunology, 2020
Daniel G Pellicci, Hui-Fern Koay, Stuart P Berzins   +2 more
exaly   +2 more sources

Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies

Nature Reviews Drug Discovery, 2019
Zsolt Sebestyén, Immo Prinz, Julie Déchanet-Merville   +2 more
exaly   +2 more sources

Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells

Science, 2020
A weird way to recognize phosphoantigens In contrast to the well-studied αβ T cells, which recognize peptide antigens presented by major histocompatibility complex (MHC) and MHC-like molecules, how γδ T cells recognize antigens remains largely a mystery.
Marc Rigau, Simone Ostrouska, Thomas S. Fulford, D. Johnson, K. Woods, Z. Ruan, Hamish E. G. McWilliam, Christopher Hudson, Candani Tutuka, A. Wheatley, S. Kent, J. Villadangos, B. Pal, C. Kurts, Jason Simmonds, M. Pelzing, A. Nash, A. Hammet, A. Verhagen, G. Vairo, E. Maraskovsky, C. Panousis, N. Gherardin, J. Cebon, D. Godfrey, A. Behren, Adam P. Uldrich   +26 more
semanticscholar   +1 more source

γδ T-cells regulate intestinal response to nutrient sensing

Science, 2021
γδ T cells link immunity to nutrition Gamma delta (γδ) T cells are immune cells best known for host barrier defenses in epithelial tissues. Sullivan et al.
Zuri A. Sullivan, William Khoury-Hanold, Jaechul Lim, C. Smillie, M. Biton, B. Reis, Rachel K. Zwick, Scott D. Pope, Kavita Israni-Winger, R. Parsa, Naomi H. Philip, Saleh Rashed, Noah W. Palm, Andrew Wang, D. Mucida, A. Regev, R. Medzhitov   +16 more
semanticscholar   +1 more source

Cancer immunotherapy by γδ T cells

Science
The premise of cancer immunotherapy is that cancers are specifically visible to an immune system tolerized to healthy self. The promise of cancer immunotherapy is that immune effector mechanisms and immunological memory can jointly eradicate cancers and ...
A. Hayday, J. Déchanet-Merville, Jamie Rossjohn, B. Silva‐Santos   +3 more
semanticscholar   +1 more source

Characterization of ascites- and tumor-infiltrating γδ T cells reveals distinct repertoires and a beneficial role in ovarian cancer

Science Translational Medicine, 2021
γδ T cells are clonotypically distinct in ascites and tumors of patients with ovarian cancer and their functionality correlates with clinical outcome.
E. Foord, Lucas C. M. Arruda, A. Gaballa, Charlotte Klynning, M. Uhlin   +4 more
semanticscholar   +1 more source