Results 121 to 130 of about 83,248 (316)

Topical administration of GLP-1 eyedrops improves retinal ganglion cell function by facilitating presynaptic GABA release in early experimental diabetes

open access: yesNeural Regeneration Research
Diabetic retinopathy is a prominent cause of blindness in adults, with early retinal ganglion cell loss contributing to visual dysfunction or blindness.
Yu-Qi Shao   +8 more
doaj   +1 more source

Crossed cerebellar diaschisis in status epilepticus: A systematic review of the literature

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Crossed cerebellar diaschisis is a neuroimaging phenomenon observed in various neurological conditions, including status epilepticus. This systematic review aims to summarize the clinical and radiological characteristics of patients developing crossed cerebellar diaschisis following status epilepticus and to discuss potential ...
Payam Tabaee Damavandi   +6 more
wiley   +1 more source

Preclinical signal for a disease‐modifying effect on seizure cluster severity with intermittent diazepam treatment

open access: yesEpilepsia, EarlyView.
Abstract Objective In epilepsy, daily treatment provides only symptomatic seizure control, leaving a significant unmet need for a treatment that affects the underlying predisposition to seizures. Here, in a first‐of‐its‐kind study, we test the hypothesis that intermittent treatment of seizure clusters with diazepam in the kainic acid post‐status ...
Qian Wu   +8 more
wiley   +1 more source

Comparison of Multiple Functional-Active Ingredients in Different Varieties of Natto

open access: yesShipin gongye ke-ji
In order to investigate the important functional-active components in different varieties of natto, natto was processed using soybean, black bean, red bean, mung bean, lentil, chickpea, kidney bean, pea, red bean and cowpea, and the differences of ...
Mengyue XU   +5 more
doaj   +1 more source

Targeting Hsp90 with cemdomespib reduces seizure burden and alters disease course in preclinical epilepsy models

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is a chronic neurological disorder characterized by recurrent seizures and frequent cognitive and psychiatric comorbidities. Although current antiseizure medications provide symptomatic relief, they fail to prevent or modify epileptogenesis.
Yara Sheeni   +8 more
wiley   +1 more source

Sex‐specific elevated incidence of glaucoma associated with topiramate versus valproate or lamotrigine in epilepsy, not migraine: A population‐based cohort study

open access: yesEpilepsia, EarlyView.
Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei   +10 more
wiley   +1 more source

Prebiotic Organic Globules [PDF]

open access: yes, 2010
Analogs of organic globules observed in carbonaceous chondrite meteorites and in interplanetary dust particles and of rod to spherical structures observed in terrestrial archean microstructures have been synthesized in our experiments conducted with ...
Marie-Paule Bassez, Yoshinori Takano
core   +1 more source

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