Results 151 to 160 of about 172,175 (356)

Protective Action of γ-Aminobutyric Acid against Oxygen Toxicity [PDF]

, 1962
J. D. Wood, William J. Watson
openalex   +1 more source

Nitrogen‐Centered Radical‐Directed C(sp3)−H Amination and Aminoalkylation Using (Diarylmethylene)amino Benziodoxolones

ChemistryEurope, EarlyView.
This report describes a C(sp3)−H aminofunctionalization via the photoexcitation of (diarylmethylene)amino benziodoxolones. These iodine reagents act as both single‐electron oxidants and nitrogen‐based SOMOphiles, serving as iminyl radicals, enabling the site‐selective C(sp3)−H amination and aminoalkylation of α‐aminoxy acid derivatives.
Kensuke Kiyokawa, Mari Sugimura, Megumi Abe, Daiki Wada, Hikaru Kaneba, Satoshi Minakata   +5 more
wiley   +1 more source

Safety and Efficacy of the NMDA‐2b‐Selective Negative Allosteric Modulator BI 1569912: A Phase Ib Randomized Trial in Major Depressive Disorder

Clinical Pharmacology &Therapeutics, EarlyView.
Selective N‐methyl‐D‐aspartate receptor subunit 2b negative allosteric modulators (NR2B NAMs) are being explored as potential new treatment options for major depressive disorder (MDD). This Phase Ib, randomized, double‐blind, placebo‐controlled, parallel‐group trial was conducted in adults (N = 59) with moderate‐to‐severe MDD and insufficient response ...
Roger S. McIntyre, Gerard Sanacora, David P. Walling, Elan A. Cohen, Shishuka Malhotra, Holger Rosenbrock, Manuela Schmitz, Andreas Scholz, Sigurd D. Süssmuth, Franco De Crescenzo   +9 more
wiley   +1 more source

Study on γ-aminobutyric acid in bananas [PDF]

, 2002
筑波大学University of Tsukuba博士（理学）Doctor of Philosophy in Science2002【要旨 ...
43748, Chek, Sotha
core  

Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

ELECTROPHORESIS, EarlyView.
ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley   +1 more source

A tight coupling between β\u3csub\u3e2\u3c/sub\u3eY97 and β\u3csub\u3e2\u3c/sub\u3eF200 of the GABA\u3csub\u3eA\u3c/sub\u3e receptor mediates GABA binding [PDF]

, 2011
The GABAA receptor is an oligopentameric chloride channel that is activated via conformation changes induced upon the binding of the endogenous ligand, GABA, to the extracellular inter-subunit interfaces. Although dozens of amino acid residues at the α/β
Laha, Kurt T., Tran, Phu N., Wagner, David A.   +2 more
core   +1 more source

Seizures and electroencephalographic findings in inborn errors of metabolism: Clues to differential diagnosis in the neonatal period, infancy, childhood and adolescence, and review of the literature

Epileptic Disorders, EarlyView.
Abstract Although inborn errors of metabolism (IEM) are a rare cause of epilepsy, seizures are a common presentation in these disorders. Seizures in IEM are frequently refractory to conventional anti‐seizure medication and might warrant initiation of specific treatments based on vitamins or dietary modifications or provision of alternative substrates ...
D. Kapoor, S. Sharma, A. Kaminska, R. Nabbout, N. Chemaly, M. Schiff, P. De Lonlay, M. Eisermann   +7 more
wiley   +1 more source

γ‐Aminobutyric acid production by culturable bacteria from the human intestine

Journal of Applied Microbiology, 2012
E. Barrett, R. Ross, R. Ross, P. O’Toole, G. Fitzgerald, C. Stanton, C. Stanton   +6 more
semanticscholar   +1 more source

CENTRAL CARDIOVASCULAR ACTIONS OF γ‐AMINOBUTYRIC ACID [PDF]

, 1964
Bhargava Kp, Shom Shanker Bhattacharya, R.C. Srimal   +2 more
openalex   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source