Results 161 to 170 of about 172,175 (356)

Resting‐state functional connectivity changes with microburst vagus nerve stimulation therapy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Microburst vagus nerve stimulation (μVNS) may reduce seizure frequency in drug‐resistant epilepsy (DRE) via targeted thalamic plasticity. We prospectively investigated the role of thalamic resting‐state functional connectivity (rsFC) in μVNS effects and hypothesized a relationship between thalamic rsFC and long‐term seizure frequency
Jane B. Allendorfer   +20 more
wiley   +1 more source

Effect of different conditions on the germination of coix seed and its characteristics analysis

open access: yesFood Chemistry: X
Coix seed (CS) has high nutritional value, but the deep processing of CS is relatively limited. Sprouting can significantly improve nutritional value, laying the foundation for efficient consumption or further processing.
Lidan Dong   +6 more
doaj  

γ-Aminobutyric acid found in fermented foods and beverages: current trends

open access: yesHeliyon, 2020
Novia R.M. Sahab   +3 more
semanticscholar   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Associations between the gut microbiota, immune cells, and different subtypes of epilepsy: A Mendelian randomization study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective The gut microbiota (GM) plays a role in epilepsy development via the microbiota–gut–brain axis. However, its relationship with various epilepsy subtypes and its mediating role through immune cells remain unclear. Thus, identifying the GM linked to specific epilepsy subtypes and investigating immune mechanisms to predict epilepsy risk,
Xu Zhang   +4 more
wiley   +1 more source

Perampanel as a second‐line therapy to midazolam reduces soman‐induced status epilepticus and neurodegeneration in rats

open access: yesEpilepsia Open, EarlyView.
Abstract Objective A benzodiazepine (diazepam or midazolam) is one of the current standards of care therapies to effectively terminate organophosphorus nerve agent‐induced status epilepticus when administered shortly after onset. Preclinical studies showed that benzodiazepines were less effective in stopping status epilepticus when treatment was ...
Hailey G. Steier   +8 more
wiley   +1 more source

Unveiling the potential biochemical effects of selected heterocyclic compounds as human Type-A γ-aminobutyric acid (GABA A) Modulator: An Insilico Approach

open access: yesBiotechnology Reports
Background: Investigating the bioactivities of zuranolone derivatives as Type-A γ-aminobutyric acid inhibitors which will thereby down-regulate postpartum depression is considered a crucial study.
Abel Kolawole Oyebamiji   +9 more
doaj  

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