Multi‐Solvent Suppression Ultrafast 2D COSY for High‐Throughput Wine Screening
An interleaved ultrafast COSY with multi‐solvent suppression was developed for wine analysis to overcome limitations often associated with 1D 1H NMR (signal overlap) and conventional 2D NMR (long acquisition times) methods. Within an acquisition time of ~20 min, it revealed hidden metabolite peaks and cross peaks for improved annotation and ...
Pia S. Mayer +5 more
wiley +1 more source
SNAT2 Amino Acid Transporter Is Regulated by Amino Acids of the SLC6 γ-Aminobutyric Acid Transporter Subfamily in Neocortical Neurons and May Play No Role in Delivering Glutamine for Glutamatergic Transmission [PDF]
Sukhjeevan Grewal +8 more
openalex +1 more source
Simultaneous Detection of GABA and Glycine Using MEGA‐PRESS With TE Optimization at 3T
ABSTRACT Purpose To achieve the simultaneous acquisition of gamma‐aminobutyric acid (GABA) and glycine (Gly) using a MEGA‐PRESS sequence with an optimized TE at 3T. Methods MEGA‐PRESS simulations were performed at TEs 60‐88 ms to determine the optimal TE for Gly detection with minimal myo‐Inositol (mI) overlap and maximal GABA detection sensitivity ...
Justin R. Singer, Kimberly L. Chan
wiley +1 more source
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz +10 more
wiley +1 more source
Updates in the Treatment of Rosacea with γ-Aminobutyric Acid Derivatives. [PDF]
Li D, Yang W, Chen N, Xu Y.
europepmc +1 more source
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
wiley +1 more source
Biochar and γ-Aminobutyric acid partnership improves rice productivity and mitigates Sb + Pb toxicity in co-contaminated soil. [PDF]
Aamer M +10 more
europepmc +1 more source
The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie +5 more
wiley +1 more source
Reduction in Soybean Flour Allergenicity Through Ball Milling Combined with γ-Aminobutyric Acid Treatment. [PDF]
Jiang L +7 more
europepmc +1 more source

