Results 221 to 230 of about 75,241 (309)

Cerebellar defects are a primary pathology in mouse models of spinal muscular atrophy

Brain Pathology, EarlyView.
Purkinje cell (PC) degeneration is localized to posterior lobules in the cerebellum, and rescue of survival motor neuron protein expression levels in motor neurons does not ameliorate this effect. Representative images of sagittal cerebellar sections stained with anti‐calbindin in the vermis and hemisphere at P12 for wild type, ChATCre+ rescue (Rescue),
Nicholas C. Cottam, Morgan Dowling, Lingling Kong, Michelle Harran Chan‐Cortés, Christine J. Charvet, Naika Norzeron, Cameron Grover, Melissa A. Harrington, Charlotte J. Sumner, Jianli Sun   +9 more
wiley   +1 more source

Enhanced GABAergic actions resulting from the coapplication of the steroid 3α-hydroxy-5α-pregnane-11,20-dione (alfaxalone) with propofol or diazepam [PDF]

, 2018
Akk, Gustav, Cao, Lily Q, Chakrabarti, Shampuma, Evers, Alex S, Germann, Allison L, Mennerick, Steven, Montana, Michael C, Shin, Daniel J, Wozniak, David F, Yuede, Carla M   +9 more
core   +1 more source

Effect of γ-aminobutyric acid on arginine phosphokinase activity in lobster axons

, 1975
Yoshitaka Maki, J. R. Cooper
openalex   +1 more source

Effects of Increased γ‐Aminobutyric Acid Levels on GAD₆₇ Protein and mRNA Levels in Rat Cerebral Cortex [PDF]

, 1993
Karin Rimvall, Sabina N. Sheikh, David L. Martin   +2 more
openalex   +1 more source

Contributions of synaptic energetic dysfunction by microtubule dynamics and microtubule‐based mitochondrial transport disorder to morphine tolerance

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Morphine is among the most powerful analgesic, but its long‐term use can cause tolerance. Synaptic ATP supply is critical for maintaining synaptic transmission. Microtubule‐based mitochondrial transport ensures synaptic energy supply.
Zheng Li, Jie Liu, Jie Ju, Xiaoling Peng, Wei Zhao, Jihao Ren, Xiaoqian Jia, Jihong Wang, Ye Tu, Feng Gao   +9 more
wiley   +1 more source

γ-Aminobutyric Acid Alleviates Programmed Cell Death in Two <i>Brassica</i> Species Under Cadmium Stress. [PDF]

Int J Mol Sci
Zhang ZW, Dang TT, Yang XY, Xie LB, Chen YE, Yuan M, Chen GD, Zeng J, Yuan S.   +8 more
europepmc   +1 more source

Chronic diazepam treatment in rats causes long‐lasting changes in central [³H]‐5‐hydroxytryptamine and [¹⁴C]‐γ‐aminobutyric acid release [PDF]

, 1990
Paul Kenneth Hitchcott, Sandra E. File, M. Ekwuru, M J Neal   +3 more
openalex   +1 more source

Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer Cells

Cell Proliferation, EarlyView.
GLS1‐mediated glutaminolysis supports GSH synthesis in cancer cells. GLS1 KO increases ROS, downregulates GPX4, and upregulates GPX1, making cells more sensitive to ferroptosis. Combining GLS1 or GPX1 inhibitors with a GPX4 inhibitor synergistically suppresses cancer growth.
Changsen Bai, Jialei Hua, Donghua Meng, Yue Xu, Benfu Zhong, Miao Liu, Zhaosong Wang, Wei Zhou, Liming Liu, Hailong Wang, Yang Liu, Lifang Li, Xiuju Chen, Yueguo Li   +13 more
wiley   +1 more source

Enhancing High-Level Food-Grade Expression of Glutamate Decarboxylase and Its Application in the Production of γ-Aminobutyric Acid. [PDF]

J Microbiol Biotechnol
Zhang K, Lv H, Yu X, Zhu X, Chen S, Wu J.   +5 more
europepmc   +1 more source

Autoradiographic Changes in Central Benzodiazepine Binding Sites and Their Coupling to γ-Aminobutyric Acid Receptors after Seizures in the Developing Rat [PDF]

, 1991
Marie‐Christine Werck, Jean‐Luc Daval   +1 more
openalex   +1 more source