Results 231 to 240 of about 172,175 (356)

Enhanced GABAergic actions resulting from the coapplication of the steroid 3α-hydroxy-5α-pregnane-11,20-dione (alfaxalone) with propofol or diazepam [PDF]

, 2018
Akk, Gustav, Cao, Lily Q, Chakrabarti, Shampuma, Evers, Alex S, Germann, Allison L, Mennerick, Steven, Montana, Michael C, Shin, Daniel J, Wozniak, David F, Yuede, Carla M   +9 more
core   +1 more source

The effects and mechanisms of stem cells and exosomes on neurological function protection and recovery after ischemic stroke

Neuroprotection, EarlyView.
Effect and mechanism of stem cells and exosomes therapy in ischemic stroke. The effect and mechanism include protection of neuron and glial cells, repairment of nerve vascular unit, reduction of inflammation response, restoration of white matter integrity, reconstruction of neural circuit, replacement of neurons and glial cells, and anti‐ferroptosis ...
Weihong Du, Yuxian He, Liangchen Li, Xinchun Jin, Panpan Geng   +4 more
wiley   +1 more source

Role of γ-Aminobutyric Acid (GABA) as an Inhibitory Neurotransmitter in Diabetes Management: Mechanisms and Therapeutic Implications. [PDF]

Biomolecules
Barakat H, Aljutaily T.
europepmc   +1 more source

Elucidating the Three‐Dimensional Structure of Piracetam through Rotational Spectroscopy

ChemistryOpen, EarlyView.
Neutral molecules of the nootropic drug piracetam are generated by laser ablation and structurally characterized by microwave spectroscopy. Two conformers differing in the exo/endo configuration of the pyrrolidine ring are detected, with exo being the predominant form.
S. Mato, S. Municio, J. L. Alonso, E. R. Alonso, I. León   +4 more
wiley   +1 more source

γ-Aminobutyric Acid Transporter Mutation GAT1 (S295L) Substantially Impairs Neurogenesis in Dentate Gyrus. [PDF]

Brain Sci
Liu W, Yang Y, Liu Y, Ni B, Zhuang H, Chen K, Shi J, Zhu C, Wang H, Fei J.   +9 more
europepmc   +1 more source

Unveiling the Therapeutic Potential of Atractylis aristata Batt. Aqueous Extract: Anti‐inflammatory, Antioxidant, Antibacterial, Sedative Activities & Phytochemical Profiling

ChemistryOpen, EarlyView.
This study evaluates the pharmacological properties of the aqueous extract of Atractylis aristata, focusing on its antioxidant, anti‐inflammatory, antibacterial, and sedative activities. Phytochemical analysis identifies bioactive compounds, while in vitro and in vivo tests demonstrate its therapeutic potential in addressing oxidative stress ...
Asma Abid, Nourelhouda Mekhadmi, Randa Mlik, Assia Bentahar, Kamilia Bireche, Bariza Frih, Walid Boussebaa, Aicha Mouane, Nezar Cherrada, Ana Sanches Silva, Messaouda Dekmouche, Lazhar Bechki, Khalid Mashay Al‐Anazi, Mohammad Abul Farah, Ahmad Ali   +14 more
wiley   +1 more source

γ-Aminobutyric Acid Intake Improves Psychological State and Performance in Esports: A Randomized, Placebo-Controlled, Double-Blind Crossover Study. [PDF]

Nutrients
Hara Y, Nakamura U, Koga K, Yamashita Y, Kim Y, Hagiwara G, Furukado R.   +6 more
europepmc   +1 more source

Effect of oral γ-aminobutyric acid (GABA) administration on sleep and its absorption in humans

Food Science and Biotechnology, 2016
Atsushi Yamatsu, Yusuke Yamashita, T. Pandharipande, I. Maru, Mujo Kim   +4 more
semanticscholar   +1 more source

Evaluation of the Sedative Activity of Naringenin: In Vivo Study with Pharmacokinetics and Molecular Docking Insights

ChemistryOpen, EarlyView.
The study investigates the sedative potential of naringenin (NAR) through in vivo and in silico approaches. NAR significantly enhances sleep duration and reduces latency in mice, especially when combined with diazepam. Molecular docking shows strong binding to GABAA receptors, suggesting a GABAergic mechanism.
Dipu Bishwas, Md. Shimul Bhuia, Salehin Sheikh, Mohammed Alfaifi, Abdul Malik, Nikhat J. Siddiqui, Divya Jain, Mehedi Hasan Bappi, Muhammad Torequl Islam   +8 more
wiley   +1 more source

From the gut to the brain, mechanisms and clinical applications of γ-aminobutyric acid (GABA) on the treatment of anxiety and insomnia. [PDF]

Front Neurosci
Jiang C, Chen Y, Sun T.
europepmc   +1 more source