Preferential superficial cortical layer activation during seizure propagation
Abstract Objective Focal cortical seizures travel long distances from the onset zone, but the long‐distance propagation pathways are uncertain. In vitro and in vivo imaging techniques have investigated the local spread of seizures but did not elucidate long‐distance spread. Furthermore, classical studies in slices suggested seizure spread locally along
Anastasia Brodovskaya+4 more
wiley +1 more source
γ-Aminobutyric Acid (GABA) Metabolic Bypass Plays a Crucial Role in Stress Tolerance and Biofilm Formation in C. sakazakii ATCC 29544. [PDF]
Wu J+6 more
europepmc +1 more source
Synaptically released glutamate reduces γ-aminobutyric acid (GABA)ergic inhibition in the hippocampus via kainate receptors [PDF]
Ming‐Yuan Min+2 more
openalex +1 more source
Fast activity chirp patterns in focal seizures from patients and animal models
Abstract Time–frequency analysis of focal seizure electroencephalographic signals performed with depth electrodes in human temporal lobe structures has revealed the occurrence at onset of oscillations at approximately 30–100 Hz that feature a monotonic rapid decay in frequency content.
Maxime Lévesque+6 more
wiley +1 more source
Dexmedetomidine Reduces Presynaptic γ-Aminobutyric Acid Release and Prolongs Postsynaptic Responses in Layer 5 Pyramidal Neurons in the Primary Somatosensory Cortex of <i>Mice</i>. [PDF]
Tang B, Tang J, Huang Y.
europepmc +1 more source
Immunity and neuroinflammation in early stages of life and epilepsy
Abstract The immune system is crucial for the correct brain development, and recent findings also point toward central control of immune response. As the immune system is not fully developed at birth, the early years become an important window for infections and for the development of epilepsy.
Angelica Vega García+5 more
wiley +1 more source
Loss of γ-aminobutyric acid D-Type Motor Neurons in Young Adult <i>Caenorhabditis elegans</i> Following Exposition with Silica Nanoparticles. [PDF]
Le DT+4 more
europepmc +1 more source
Biochemical Properties of γ-Aminobutyric Acid(GABA) Receptor
Kinya Kuriyama+4 more
openalex +1 more source
Toward molecular phenotyping of temporal lobe epilepsy by spatial omics
Abstract Objective In temporal lobe epilepsy (TLE), detection of the epileptogenic zone predicts a good surgical outcome. When submitted to 18F‐fluorodeoxyglucose positron emission tomography (PET), some patients display lateralized, focal hypometabolism in the temporal lobe (PET+), whereas others appear normometabolic (PET−).
Isabeau Vermeulen+33 more
wiley +1 more source