Results 261 to 270 of about 83,248 (316)

Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy

Epilepsia, EarlyView.
Abstract Objective Absence epilepsy is characterized by brief but frequent seizures with loss of consciousness. Existing treatments, which come with heavy side effects, are only partially effective and do not address the associated comorbidities, including cognitive and social deficits.
Coline Rulhe, Steeve Thirard, Juri Aparicio Arias, Leila Makrini, Florence Fauvelle, Emmanuelle Beyne, Alexandra Dauvé, Tristan Bouschet, Emmanuel Valjent, Federica Bertaso   +9 more
wiley   +1 more source

The Regulation of γ-Aminobutyric Acid on Antioxidative Defense Response of Pacific Oyster upon High-Temperature Stress. [PDF]

Antioxidants (Basel)
Liu R, Gao L, Zhang X, Ge P, Wang L, Zhou K, Yang C, Wang L, Song L.   +8 more
europepmc   +1 more source

Epilepsy treatment over time: The chess game analogy for choosing, adjusting, and adding antiseizure medications

Epilepsia, EarlyView.
Abstract Recurrent seizures have such a negative impact upon the lives of persons with epilepsy that their prevention is a constant preoccupation of neurologists. Despite the large number of antiseizure medications (ASMs) currently available and of publications on their putative efficacy, adverse effects, and order of preference to start treatment ...
André Palmini, André Gus, Lecio Figueira Pinto   +2 more
wiley   +1 more source

Unraveling the Potential of γ-Aminobutyric Acid: Insights into Its Biosynthesis and Biotechnological Applications. [PDF]

Nutrients
Zhu L, Wang Z, Gao L, Chen X.
europepmc   +1 more source

Impact of long‐term treatment with cenobamate on concomitant usage of antiseizure medications: A real‐world retrospective study in Spain

Epilepsia, EarlyView.
Abstract Objectives This study explored the safety and effectiveness of adjunctive cenobamate (CNB) in patients with different levels of drug‐resistant epilepsy (DRE) in a real‐world setting, including its impact on the use of co‐antiseizure medication (co‐ASM). Methods This was a single‐center, retrospective, observational study.
Juan María Sánchez‐Caro, Roshan Hariramani Ramchandani, Iratxe Maestro Saiz, Juan Jesús Rodríguez Uranga   +3 more
wiley   +1 more source

γ-Aminobutyric Acid Alleviates Programmed Cell Death in Two <i>Brassica</i> Species Under Cadmium Stress. [PDF]

Int J Mol Sci
Zhang ZW, Dang TT, Yang XY, Xie LB, Chen YE, Yuan M, Chen GD, Zeng J, Yuan S.   +8 more
europepmc   +1 more source

Spreading depolarization and its influence on epileptiform activity

Epilepsia, EarlyView.
Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque, Rüdiger Köhling, Massimo Avoli   +2 more
wiley   +1 more source

Process Optimization and Quality Components Analysis of γ-Aminobutyric Acid Pickled Tea. [PDF]

Foods
Luo Q, Li Q, Li J, Xu W, Lin L.
europepmc   +1 more source

Exogenous γ-Aminobutyric Acid Improves the Structure and Function of Photosystem II in Muskmelon Seedlings Exposed to Salinity-Alkalinity Stress

, 2016
Lixia Xiang, Lipan Hu, Weinan Xu, Ai Zhen, Liang Zhang, Xiaohui Hu   +5 more
openalex   +2 more sources

Cognitive stagnation and executive function deficits in young children with SCN1A+ Dravet syndrome: Detailed characterization of onset, progression, and impact in the ENVISION natural history study

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a developmental and epileptic encephalopathy characterized by drug‐resistant seizures and developmental slowing. Although cognitive and executive function deficits have been described, their early trajectory is not well understood.
Joseph Sullivan, M. Scott Perry, Ingrid E. Scheffer, James Wheless, Susana Boronat, Andreas Brunklaus, Linda Laux, Anup D. Patel, Colin Roberts, Dennis Dlugos, Deborah Holder, Kelly Knupp, Matt Lallas, Steven Phillips, Eric Segal, Dennis Lal, Elaine Wirrell, Sameer Zuberi, Gerard Gioia, Rebecca Shaffer, Madison M. Berl, Mary Wojnaroski, Sarah Christensen, Alexander King, Emma S. James, Maria Candida Vila, Norman Huang, Jacqueline S. Gofshteyn, Salvador Rico   +28 more
wiley   +1 more source