Results 21 to 30 of about 83,248 (316)

INTERACTION OF Γ AMINOBUTYRIC ACID B RECEPTORS AND ELECTROMAGNETIC FIELD IN THE FEAR RESPONSE [PDF]

American Journal of Neuroscience, 2013
One of the most neurotransmission system consistently linked with fear response is GABAergic system. GABA through GABAB receptor can influence fear response. The aim of the present investigation was to examine the effect of IP injection of baclofen (GABAB agonist) and CGP35348 (GABAB antagonist) along with EMF exposure on frequency of fear response ...
openaire   +1 more source

Regulation of Arabidopsis 14-3-3 gene expression by GABA. [PDF]

, 2006
The function in plants of the non-protein amino acid, gamma-aminobutyric acid (GABA) is poorly understood. In this study, we show that GABA down-regulates the expression of a large sub-set of 14-3-3 gene family members in Arabidopsis thaliana seedlings ...
Lancien, Muriel, Roberts, Michael R
core   +1 more source

Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit [PDF]

, 2008
The characterization of a new class of pyrrole−imidazole hairpin polyamides with β-amino-γ-turn units for recognition of the DNA minor groove is reported.
Chenoweth, David M., Dervan, Peter B., Dose, Christian, Farkas, Michelle E.   +3 more
core   +2 more sources

Effect of Ultrasonic Induction on the Main Physiological and Biochemical Indicators and γ–Aminobutyric Acid Content of Maize during Germination

Foods, 2022
Research on the nutrient content of cereal grains during germination is becoming a hot topic; however, studies on germinated maize are still scarce. This study aimed to provide a technical reference and theoretical basis for the development of functional
Liangchen Zhang, Nan Hao, Wenjuan Li, Baiqing Zhang, Taiyuan Shi, Mengxi Xie, Miao Yu   +6 more
doaj   +1 more source

Homozygosity for a missense mutation in the 67 kDa isoform of glutamate decarboxylase in a family with autosomal recessive spastic cerebral palsy: parallels with Stiff-Person Syndrome and other movement disorders [PDF]

, 2004
Background Cerebral palsy (CP) is an heterogeneous group of neurological disorders of movement and/or posture, with an estimated incidence of 1 in 1000 live births.
A Lernmark, Alex F Markham, B Hagberg, BG Condie, C Geoffrey Woods, CL Fawer, Clare N Lynex, CM Wiles, David T Bonthon, DF Bu, DF Bu, DJ Stone, DL Martin, DL Martin, DP McHale, DP McHale, E Maestrini, Eamonn R Maher, F Sandbrink, G Gaffney, GE Homanics, H Asada, H Mitoma, HM Meinck, I Hughes, Ian M Carr, J Kim, J Volpe, Jack P Leek, JO Forfar, JS Lappalainen, K Burk, K Dinkel, KCK Kuban, KH Gustavson, LM Dubowitz, LM Levy, M Baraitser, M Solimena, M Solimena, MC Dalakas, MG Erlander, MH Butler, N Laprade, N Paneth, POD Pharoah, PS Eicher, PT Bosma, Rajgopal Achuthan, RW Bond, S Bundey, S Chattopadhyay, S Kono, S Kure, S Mitchell, SD Chessler, Simon Mitchell, V Cormier-Daire   +57 more
core   +2 more sources

Temperature dependence of the microwave dielectric properties of $$\gamma$$ γ -aminobutyric acid

Scientific Reports, 2021
The GABA molecule is the major inhibitory neurotransmitter in the mammalian central nervous system. Through binding to post-synaptic neurons, GABA reduces the neuronal excitability by hyperpolarization.
Jie Hou, Sisay Mebre Abie, Runar Strand-Amundsen, Yuri M. Galperin, Joakim Bergli, Christin Schuelke, Sina Hashemizadeh, Ørjan Grøttem Martinsen   +7 more
doaj   +1 more source

Beyond the γ-aminobutyric acid hypothesis of schizophrenia

Frontiers in Cellular Neuroscience, 2023
Abnormalities in the γ-aminobutyric acid (GABA) system have been reported in the postmortem brains of individuals with schizophrenia. In particular, the reduction of one of the GABA-synthesizing enzymes, the 67-kDa isoform of glutamate decarboxylase ...
Kazuyuki Fujihara, Kazuyuki Fujihara
doaj   +1 more source

Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication. [PDF]

, 2017
A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication.
Dang, Hoa, Kaufman, Daniel L, Middleton, Blake, Tian, Jide   +3 more
core   +1 more source

Methylenetetrahydrofolate reductase deficiency alters levels of glutamate and γ-aminobutyric acid in brain tissue

Molecular Genetics and Metabolism Reports, 2015
Methylenetetrahydrofolate reductase (MTHFR) is an enzyme key regulator in folate metabolism. Deficiencies in MTHFR result in increased levels of homocysteine, which leads to reduced levels of S-adenosylmethionine (SAM).
N.M. Jadavji, F. Wieske, U. Dirnagl, C. Winter   +3 more
doaj   +1 more source

The use of deuterium-labeled gamma-aminobutyric (D6-GABA) to study uptake, translocation, and metabolism of exogenous GABA in plants

Plant Methods, 2020
Background Exogenous application of gamma-aminobutyric acid (GABA) could relieve stress symptoms caused by abiotic stresses including anoxia, heat and cold shock, drought, and salt.
Faraj Hijaz, Nabil Killiny
doaj   +1 more source