Results 291 to 300 of about 172,175 (356)

Design, Synthesis and Biological Activity Study of γ-Aminobutyric Acid (GABA) Derivatives Containing Bridged Bicyclic Skeletons as BCAT1 Inhibitors. [PDF]

Molecules
Luo W, Pan Z, Zhu X, Li Y, Li Y, Zhang Y, Pan J, Ding J, Xie H, Zhao G.   +9 more
europepmc   +1 more source

EEG signal dimension is an index of seizure propensity and antiseizure medication effects in a mouse model of acquired epilepsy

Epilepsia, EarlyView.
Abstract Objective Variability in the frequency, timing, and pattern of seizures may influence the assessment of the effect of antiseizure medications (ASMs) when measuring seizure frequency, especially in patients with infrequent seizures. A low seizure rate is an exclusion criterion for enrollment of patients with epilepsy in clinical trials and ...
Massimo Rizzi, Peter J. West, Annamaria Vezzani, Karen S. Wilcox, Alessandro Giuliani   +4 more
wiley   +1 more source

Effect of Exogenous γ-Aminobutyric Acid (GABA) on the Growth, Photosynthetic Pigment, Antioxidant and GABA Metabolism of Festuca arundinacea (Tall Fescues) Under Cadmium Stress. [PDF]

Plants (Basel)
Geng W, Zhang Y, Li C, Song G, Shi S.
europepmc   +1 more source

Synaptic inhibitory dynamics drive benzodiazepine response in pediatric status epilepticus

Epilepsia, EarlyView.
Abstract Objective Pediatric status epilepticus (SE) is a medical emergency associated with significant morbidity. Benzodiazepines (BZPs) are the current first‐line treatment, but do not work in more than one third of children presenting with SE. Animal studies have shown that SE can cause changes in synaptic inhibition signaling that can ultimately ...
Tommaso Fedele, Richard J. Burman, Anne Steinberg, Giorgio Selmin, Georgia Ramantani, Richard E. Rosch   +5 more
wiley   +1 more source

Anti-γ-aminobutyric acid-B receptor autoimmune encephalitis with syncope as the initial symptom: Case report and literature review. [PDF]

Open Life Sci
Zhang D, Xu Z, Wu J, Wei W, Li X, Chen X.   +5 more
europepmc   +1 more source

kcnb1 loss of function in zebrafish causes neurodevelopmental and epileptic disorders associated with γ‐aminobutyric acid dysregulation

Epilepsia, EarlyView.
Abstract Objective KCNB1 encodes an α‐subunit of the delayed‐rectifier voltage‐dependent potassium channel Kv2.1. De novo pathogenic variants of KCNB1 have been linked to developmental and epileptic encephalopathies (DEEs), diagnosed in early childhood and sharing limited treatment options.
Lauralee Robichon, Claire Bar, Anca Marian, Lisa Lehmann, Solène Renault, Edor Kabashi, Sorana Ciura, Rima Nabbout   +7 more
wiley   +1 more source

Physiology of γ-aminobutyric acid production by Akkermansia muciniphila. [PDF]

Appl Environ Microbiol
Konstanti P, Ligthart K, Fryganas C, Constantinos P, Smidt H, de Vos WM, Belzer C.   +6 more
europepmc   +1 more source

Prevalence, clinical characteristics, and risk factors for psychosis in people with epilepsy: A multicenter retrospective cohort study

Epilepsia, EarlyView.
Abstract Objective We aimed to assess the prevalence, clinical characteristics, and risk factors for psychosis in a cohort of people with epilepsy in West China. Methods We used retrospective information from databases of three tertiary epilepsy centers, which included follow‐up records from 2006 onward.
Sisi Shen, Hanlin Sun, Zaiquan Dong, Tong Yi, Josemir W. Sander, Dong Zhou, Jinmei Li   +6 more
wiley   +1 more source

Production and quality evaluation of a novel γ-aminobutyric acid-enriched yogurt. [PDF]

Front Nutr
Zhu F, Hu S, Mei L.
europepmc   +1 more source