Results 291 to 300 of about 75,241 (309)

Neuronal oscillatory imbalances in GNAO1‐related disorders associated with disease severity

open access: yesEpilepsia, EarlyView.
Abstract Objective This study investigates excitatory/inhibitory (E/I) imbalances in GNAO1‐related disorders (GNAO1‐RD), linking neuronal dysfunction to clinical severity using E/I‐sensitive electroencephalography (EEG) analyses. Methods We conducted an observational study involving 12 children with GNAO1‐RD caused by pathogenic variants and 36 age ...
Tongyu Wang   +8 more
wiley   +1 more source

Cannabidiol attenuates epileptic phenotype and increases survival in a mouse model of developmental and epileptic encephalopathy type 1

open access: yesEpilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathy type 1 (DEE1) is a rare drug‐resistant pediatric epilepsy caused by trinucleotide repeat expansions in the X‐linked ARX gene, leading to elongation of the first polyalanine tract. It presents with early onset tonic seizures or spasms, developmental and cognition delay, and high risk of ...
Lucia Verrillo   +9 more
wiley   +1 more source

In vivo and in silico models of Drosophila for Parkinson's disease

open access: yesThe FEBS Journal, EarlyView.
In vivo and in silico models of Drosophila offer valuable advantages in the generation, analysis, and interpretation of complex biological data, thereby significantly advancing our understanding of Parkinson's disease. Molecular‐level measurements and phenotypic data from Drosophila are extensively utilised in metabolic network modeling and artificial ...
Müberra Fatma Cesur   +3 more
wiley   +1 more source

Neurosyphilis complicated by anti-γ-aminobutyric acid-B receptor encephalitis: A case report. [PDF]

open access: yesWorld J Clin Cases
Fang YX   +9 more
europepmc   +1 more source

Anti‐melanogenic effects of Medicago sativa seed extracts on melanocytes

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Our study demonstrated that two types of alfalfa seed extract: alfalfa ethanol precipitate (AEP) and alfalfa ethanol supernatant (AES) inhibited melanogenesis through the downregulation of tyrosinase expression, following the inactivation of CREB, b‐catenin and ERK signalling pathway in α‐melanocyte‐stimulating hormone (α‐MSH)‐stimulated B16F10 mouse ...
Chae Rin Kim   +7 more
wiley   +1 more source

Single‐Step Genome‐Wide Association Study of Factors for Evaluated and Linearly Scored Traits in Swedish Warmblood Horses

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Swedish Warmblood horses (SWB) are bred for show jumping and/or dressage with young horse test scores as indicator traits. This study aimed to investigate possible candidate genes and regions of importance for evaluated and linearly scored young horse test traits.
Anahit Nazari‐Ghadikolaei   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy