Results 311 to 320 of about 172,175 (356)

Cortico‐cortical evoked potentials: Analytical techniques and emerging paradigms for epileptogenic zone localization

Epilepsia, EarlyView.
Abstract Cortico‐cortical evoked potentials (CCEPs) are an active electrophysiological technique used during intracranial electroencephalography to evaluate the effective connectivity and influence of therapeutic stimulation between distinct cortical regions and pinpoint epileptogenic zones (EZs) in patients with epilepsy.
Zekai Qiang, Jamie Norris, Gerald Cooray, Richard Rosch, Kai Miller, Dora Hermes, Aswin Chari, Martin Tisdall   +7 more
wiley   +1 more source

Stress-Driven Production of γ-Aminobutyric Acid Using Non-Conventional Yeast Strains Kluyveromyces marxianus JMY140K and Metschnikowia reukaufii JMY075. [PDF]

J Fungi (Basel)
Fan TT, Chen C, Zeng DW, Wang FL, Xu ZX, Jin MJ, Zou Y, Li J, Zhao XQ.   +8 more
europepmc   +1 more source

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications. 1. Use of the EEG in drug development and characteristics of the model

Epilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof‐of‐principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalography (EEG) response (PPR) as a surrogate for seizures, is currently the only human model that allows POP trials of investigational compounds after ...
Dorothée Kasteleijn‐Nolst Trenité, Wolfgang Löscher   +1 more
wiley   +1 more source

Lacticaseibacillus rhamnosus LRJ-1 alleviates constipation through promoting gut Bacteroides-derived γ-aminobutyric acid production. [PDF]

Curr Res Food Sci
Xia T, Huang F, Yun F, Liu Y, Wang T, Wang S, Jin S, Ma X, Wang W, He J, Teng K, Zhong J.   +11 more
europepmc   +1 more source

Contribution of perineuronal nets to hyperexcitability in pilocarpine‐induced status epilepticus

Epilepsia, EarlyView.
Abstract Objective Changes in extracellular matrix (ECM) and highly condensed ECM structures called perineuronal nets (PNNs) have been reported in human patients with epilepsy as well as some animal models of epilepsy. We studied potential ECM changes in a mouse model of pilocarpine‐induced status epilepticus (PISE) and their potential contributions to
AnnaLin M. Woo, Erik J. Fleischel, Dipan C. Patel, Harald Sontheimer   +3 more
wiley   +1 more source

MdSINA2-MdNAC104 Module Regulates Apple Alkaline Resistance by Affecting γ-Aminobutyric Acid Synthesis and Transport. [PDF]

Adv Sci (Weinh)
Li Y, Tian X, Liu T, Shi Y, Li Y, Wang H, Cui Y, Lu S, Gong X, Mao K, Li M, Ma F, Li C.   +12 more
europepmc   +1 more source

Intersection of epilepsy and cardiac health: Insights from electrocardiography and syndromic associations

Epilepsia, EarlyView.
Abstract Epilepsy is a chronic neurological condition marked by recurrent, uncontrolled seizures. Identifying comorbidities in epilepsy is critical for preventing mortality. Among these, the autonomic nervous system's role in epilepsy often manifests as cardiac disorders. Patients with epilepsy (PWE), particularly those with poorly controlled seizures,
Enes Akyuz, Feyza Sule Aslan, Tugba Eyigurbuz   +2 more
wiley   +1 more source

GABRA2‐related encephalopathy: Identification of two phenotypes with distinctive electroclinical features

Epilepsia, EarlyView.
Abstract Pathogenic variants in γ‐aminobutyric acid type A (GABAA) receptor subunit genes are increasingly associated with epilepsy and neurodevelopmental disorders. Pathogenic variants in GABRA2, encoding the α‐2 subunit of GABAA receptors, have been recently reported.
Marie Adamo‐Croux, Chloé Angelini, Jérôme Aupy, Laurent Villard, Nathalie Villeneuve, Arnaud Chefdor, Yorsa Halleb, Maxime Colmard, Manon Degoutin, Gaetan Lesca, Perrine Charles, Boris Keren, Nicole Chemaly, Cyril Goizet, Mathieu Milh, Claire Bar   +15 more
wiley   +1 more source

Unveiling the potential of A. fabrum and γ-aminobutyric acid for mitigation of nickel toxicity in fenugreek. [PDF]

Sci Rep
Danish S, Hussain GS, Hussain MB, Elgorban AM, Datta R.   +4 more
europepmc   +1 more source

Neuronal oscillatory imbalances in GNAO1‐related disorders associated with disease severity

Epilepsia, EarlyView.
Abstract Objective This study investigates excitatory/inhibitory (E/I) imbalances in GNAO1‐related disorders (GNAO1‐RD), linking neuronal dysfunction to clinical severity using E/I‐sensitive electroencephalography (EEG) analyses. Methods We conducted an observational study involving 12 children with GNAO1‐RD caused by pathogenic variants and 36 age ...
Tongyu Wang, Jana Domínguez‐Carral, William Grant Ludlam, Mar Junyent Segarra, Montserrat Fornaguera Marti, Hilgo Bruining, Kirill A. Martemyanov, Klaus Linkenkaer‐Hansen, Juan Dario Ortigoza‐Escobar   +8 more
wiley   +1 more source