Results 41 to 50 of about 75,241 (309)

Emerging Roles of γ Aminobutyric Acid (GABA) Gated Channels in Plant Stress Tolerance

Plants, 2021
The signaling role for γ-Aminobutyric acid (GABA) has been documented in animals for over seven decades. However, a signaling role for GABA in plants is just beginning to emerge with the discovery of putative GABA binding site/s and GABA regulation of ...
Mona Kaspal, Madhuka H. Kanapaddalagamage, Sunita A. Ramesh   +2 more
doaj   +1 more source

Regulation of Arabidopsis 14-3-3 gene expression by GABA. [PDF]

, 2006
The function in plants of the non-protein amino acid, gamma-aminobutyric acid (GABA) is poorly understood. In this study, we show that GABA down-regulates the expression of a large sub-set of 14-3-3 gene family members in Arabidopsis thaliana seedlings ...
Lancien, Muriel, Roberts, Michael R
core   +1 more source

Stereochemical control of the DNA binding affinity, sequence specificity, and orientation preference of chiral hairpin polyamides in the minor groove [PDF]

, 1998
Three-ring polyamides containing pyrrole (Py) and imidazole (Im) amino acids covalently coupled by γ-aminobutyric acid (γ) form six-ring hairpins that recognize five-base-pair sequences in the minor groove of DNA.
Baird, Eldon E., Dervan, Peter B., Herman, David M.   +2 more
core   +1 more source

Picrotoxin Delineates Different Transport Configurations for Malate and γ Aminobutyric Acid through TaALMT1

Biology, 2022
Plant-derived pharmacological agents have been used extensively to dissect the structure–function relationships of mammalian GABA receptors and ion channels. Picrotoxin is a non-competitive antagonist of mammalian GABAA receptors.
Sunita A. Ramesh, Yu Long, Abolfazl Dashtbani-Roozbehani, Matthew Gilliham, Melissa H. Brown, Stephen D. Tyerman   +5 more
doaj   +1 more source

Homozygosity for a missense mutation in the 67 kDa isoform of glutamate decarboxylase in a family with autosomal recessive spastic cerebral palsy: parallels with Stiff-Person Syndrome and other movement disorders [PDF]

, 2004
Background Cerebral palsy (CP) is an heterogeneous group of neurological disorders of movement and/or posture, with an estimated incidence of 1 in 1000 live births.
A Lernmark, Alex F Markham, B Hagberg, BG Condie, C Geoffrey Woods, CL Fawer, Clare N Lynex, CM Wiles, David T Bonthon, DF Bu, DF Bu, DJ Stone, DL Martin, DL Martin, DP McHale, DP McHale, E Maestrini, Eamonn R Maher, F Sandbrink, G Gaffney, GE Homanics, H Asada, H Mitoma, HM Meinck, I Hughes, Ian M Carr, J Kim, J Volpe, Jack P Leek, JO Forfar, JS Lappalainen, K Burk, K Dinkel, KCK Kuban, KH Gustavson, LM Dubowitz, LM Levy, M Baraitser, M Solimena, M Solimena, MC Dalakas, MG Erlander, MH Butler, N Laprade, N Paneth, POD Pharoah, PS Eicher, PT Bosma, Rajgopal Achuthan, RW Bond, S Bundey, S Chattopadhyay, S Kono, S Kure, S Mitchell, SD Chessler, Simon Mitchell, V Cormier-Daire   +57 more
core   +2 more sources

Chronic antipsychotic treatment differentially modulates protein kinase A- and glycogen synthase kinase 3 beta-dependent signaling pathways, N-methyl-D-aspartate receptor and γ-aminobutyric acid A receptors in nucleus accumbens of juvenile rats

Journal of Psychopharmacology, 2018
Background: Antipsychotics are developed to treat mental disorders in adults; however, the prescription (mostly “off-label”) of antipsychotics for children/adolescents has been constantly increasing over years. The influences of antipsychotics on juveniles requires investigation to validate their clinic use.
Jiamei Lian, Bo Pan, Chao Deng, Chao Deng   +3 more
openaire   +5 more sources

Non-Targeted Metabolomics Analysis of γ–Aminobutyric Acid Enrichment in Germinated Maize Induced by Pulsed Light

Foods
Pulsed light is an emerging technique in plant physiology recognized for its ability to enhance germination and accumulate γ–aminobutyric acid in maize.
Liangchen Zhang, Xiaojing Liu, Liwei Xu, Mengxi Xie, Miao Yu   +4 more
doaj   +1 more source

Effects of Different Treatments on Nutritional Composition and Antioxidant Activity of Rice Buckwheat

Shipin gongye ke-ji, 2022
In order to study the influence of different treatment methods on the nutritional composition and biological activity of rice buckwheat, germination, fermentation, steaming and fermentation after steaming on the reducing sugar, protein, free amino acids,
Jing YAN, Yixi CAI, Qiuyan XUE, Junjian LI, Pan LI, Bing DU   +5 more
doaj   +1 more source

γ-Aminobutyric Acid Increases the Water Accessibility of M3 Membrane-Spanning Segment Residues in γ-Aminobutyric Acid Type A Receptors [PDF]

, 1999
γ-Aminobutyric acid type A (GABAA) receptors are members of the ligand-gated ion channel gene superfamily. Using the substituted cysteine accessibility method, we investigated whether residues in the α1M3 membrane-spanning segment are water-accessible ...
Akabas, Akabas, Akabas, Altschul, Amin, Amin, Backus, Baenziger, Baker, Baldwin, Belelli, Blanton, Blanton, Boyer, Campos-Caro, Cha, Chang, Changeux, Colquhoun, Corbin, Daniel B. Williams, Danielson, Donnelly, Englander, Farrar, Fu, Gorne-Tschelnokow, Gray, Hasinoff, Holmgren, Horenstein, Jackson, Jackson, Javitch, Javitch, Javitch, Jones, Karlin, Koltchine, Krasowski, Krasowski, Lester, Lugovskoy, Macdonald, MacDonald, Maconochie, McKernan, Methot, Methot, Mihic, Myles H. Akabas, Nayeem, Olami, Pascual, Rabow, Roberts, Schofield, Sigel, Simpson, Study, Tretter, Unwin, VanSteveninck, Wang, Waugh, Wick, Wingrove, Wisden, Xu, Xu, Xu, Yang, Yu, Zhang   +73 more
core   +1 more source

Development and Techno-Economic Evaluation of Crystallization Techniques for GABA Purification from Fermentation Broth

Molecules
γ-aminobutyric acid, a critical neurotransmitter, is experiencing an increasing demand in the medical and health fields. Conventional processes for γ-aminobutyric acid purification from fermentation broth encounter significant challenges, such as high ...
Yu Jing, Jinxu Zhang, Shengping You, Mengfan Wang, Rongxin Su, Wei Qi   +5 more
doaj   +1 more source