Results 41 to 50 of about 172,175 (356)

Methylenetetrahydrofolate reductase deficiency alters levels of glutamate and γ-aminobutyric acid in brain tissue

open access: yesMolecular Genetics and Metabolism Reports, 2015
Methylenetetrahydrofolate reductase (MTHFR) is an enzyme key regulator in folate metabolism. Deficiencies in MTHFR result in increased levels of homocysteine, which leads to reduced levels of S-adenosylmethionine (SAM).
N.M. Jadavji   +3 more
doaj   +1 more source

Temperature dependence of the microwave dielectric properties of $$\gamma$$ γ -aminobutyric acid

open access: yesScientific Reports, 2021
The GABA molecule is the major inhibitory neurotransmitter in the mammalian central nervous system. Through binding to post-synaptic neurons, GABA reduces the neuronal excitability by hyperpolarization.
Jie Hou   +7 more
doaj   +1 more source

Effect of Ultrasonic Induction on the Main Physiological and Biochemical Indicators and γ–Aminobutyric Acid Content of Maize during Germination

open access: yesFoods, 2022
Research on the nutrient content of cereal grains during germination is becoming a hot topic; however, studies on germinated maize are still scarce. This study aimed to provide a technical reference and theoretical basis for the development of functional
Liangchen Zhang   +6 more
doaj   +1 more source

Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]

open access: yes, 2014
BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core   +2 more sources

The use of deuterium-labeled gamma-aminobutyric (D6-GABA) to study uptake, translocation, and metabolism of exogenous GABA in plants

open access: yesPlant Methods, 2020
Background Exogenous application of gamma-aminobutyric acid (GABA) could relieve stress symptoms caused by abiotic stresses including anoxia, heat and cold shock, drought, and salt.
Faraj Hijaz, Nabil Killiny
doaj   +1 more source

Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit [PDF]

open access: yes, 2008
The characterization of a new class of pyrrole−imidazole hairpin polyamides with β-amino-γ-turn units for recognition of the DNA minor groove is reported.
Chenoweth, David M.   +3 more
core   +2 more sources

Exploring the contributions of two glutamate decarboxylase isozymes in Lactobacillus brevis to acid resistance and γ-aminobutyric acid production

open access: yesMicrobial Cell Factories, 2018
BackgroundThe glutamate decarboxylase (GAD) system of Lactobacillus brevis involves two isoforms of GAD, GadA and GadB, which catalyze the conversion of L-glutamate to γ-aminobutyric acid (GABA) in a proton-consuming reaction contributing to ...
C. Lyu   +8 more
semanticscholar   +1 more source

Study on Processing Technology and Quality of Moringa oleifera leaves with y - Aminobutyric Acid

open access: yesMATEC Web of Conferences, 2017
In order to obtain the high level of γ-aminobutyric acid Moringa oleifera leaves, Use 7% sodium glutamate solution to soak the fresh Moringa oleifera leaves, study effect of different treatment times and three different drying methods( hot air drying ...
Wei Zhou   +6 more
doaj   +1 more source

Emerging Roles of γ Aminobutyric Acid (GABA) Gated Channels in Plant Stress Tolerance

open access: yesPlants, 2021
The signaling role for γ-Aminobutyric acid (GABA) has been documented in animals for over seven decades. However, a signaling role for GABA in plants is just beginning to emerge with the discovery of putative GABA binding site/s and GABA regulation of ...
Mona Kaspal   +2 more
doaj   +1 more source

γ‐Aminobutyric acid receptor alpha 1 subunit loss of function causes genetic generalized epilepsy by impairing inhibitory network neurodevelopment

open access: yesEpilepsia, 2018
In humans, mutations of the γ‐aminobutyric acid receptor subunit 1 (GABRA1) cause either mild or severe generalized epilepsy. Although these epilepsy‐causing mutations have been shown to disrupt the receptor activity in vitro, their in vivo consequences ...
É. Samarut   +10 more
semanticscholar   +1 more source

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