Results 41 to 50 of about 83,248 (316)

Effects of Different Treatments on Nutritional Composition and Antioxidant Activity of Rice Buckwheat

Shipin gongye ke-ji, 2022
In order to study the influence of different treatment methods on the nutritional composition and biological activity of rice buckwheat, germination, fermentation, steaming and fermentation after steaming on the reducing sugar, protein, free amino acids,
Jing YAN, Yixi CAI, Qiuyan XUE, Junjian LI, Pan LI, Bing DU   +5 more
doaj   +1 more source

Modulation of the GABAergic pathway for the treatment of fragile X syndrome. [PDF]

, 2014
Fragile X syndrome (FXS) is the most common genetic cause of intellectual disability and the most common single-gene cause of autism. It is caused by mutations on the fragile X mental retardation gene (FMR1) and lack of fragile X mental retardation ...
Hagerman, Randi J, Hare, Emma B, Lozano, Reymundo   +2 more
core   +1 more source

Development and Techno-Economic Evaluation of Crystallization Techniques for GABA Purification from Fermentation Broth

Molecules
γ-aminobutyric acid, a critical neurotransmitter, is experiencing an increasing demand in the medical and health fields. Conventional processes for γ-aminobutyric acid purification from fermentation broth encounter significant challenges, such as high ...
Yu Jing, Jinxu Zhang, Shengping You, Mengfan Wang, Rongxin Su, Wei Qi   +5 more
doaj   +1 more source

MOESM1 of OsProT1 and OsProT3 Function to Mediate Proline- and γ-aminobutyric acid-specific Transport in Yeast and are Differentially Expressed in Rice (Oryza sativa L.)

, 2019
Additional file 1: Figure S1. Alignment of OsProT proteins. Figure S2. Expression levels of OsProT2 in different organs at vegetative and reproductive stages. Figure S3. OsProT2 transcript levels in rice plants under different abiotic stress conditions. Table S1. The primers used in this study.
Lin, Jin-Hong, Xu, Zhi-Jun, Peng, Jia-Shi, Zhao, Jing, Zhang, Guo-Bin, Xie, Jun, Yi, Zhen-Xie, Zhang, Jian-Hua, Gong, Ji-Ming, Ye, Neng-Hui, Meng, Shuan   +10 more
openaire   +1 more source

Migraine and cluster headache show impaired neurosteroids patterns [PDF]

, 2019
Background: Perturbation of neuronal excitability contributes to migraine. Neurosteroids modulate the activity of γ-aminobutyric acid A and N-methyl-d-aspartate receptors, and might be involved in the pathogenesis of migraine.
Capi, M., Cicione, C., De Marco, C. M., Di Menna, L., Guglielmetti, M., Koverech, A., Lionetto, L., Maestri, M., Martelletti, P., Negro, A., Nicoletti, F., Passariello, F., Sabbatini, E., Simmaco, M.   +13 more
core   +1 more source

Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membrane

Nature Communications, 2023
GABAB receptors mediate the effects of the main inhibitory neurotransmitter in the brain. Here, authors identify the cytoskeletal protein filamin A as a key player that controls the exact location and function of GABAB receptors at the cell surface.
Marie-Lise Jobin, Sana Siddig, Zsombor Koszegi, Yann Lanoiselée, Vladimir Khayenko, Titiwat Sungkaworn, Christian Werner, Kerstin Seier, Christin Misigaiski, Giovanna Mantovani, Markus Sauer, Hans M. Maric, Davide Calebiro   +12 more
doaj   +1 more source

Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures [PDF]

, 2019
The fidelity of inhibitory neurotransmission is dependent on the accumulation of γ-aminobutyric acid type A receptors (GABAARs) at the appropriate synaptic sites.
Andrews, Peter M., Brandon, Nicholas J., Davies, Paul A., Hines, Rochelle M., Moore, Yvonne E., Moss, Stephen J., Nathanson, Anna J., Ollerhead, Thomas A., Rodriguez Santos, Miguel A., Smalley, Joshua L., Wobst, Heike J., Zhang, Yihui   +11 more
core   +2 more sources

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Transport properties of aqueous solution of γ-aminobutyric acid

AIP Advances, 2022
Transportation of amino acids throughout the body is an essential mechanism to support life processes. Transportation phenomena such as diffusion, viscosity, etc., of amino acids in an aqueous medium are useful to understand their inter- and intra ...
Shyam P. Khanal, Rajendra P. Koirala, Esha Mishra, Narayan P. Adhikari   +3 more
doaj   +1 more source