Results 61 to 70 of about 26,551 (120)

Molecular Dynamics Activation of γ-Secretase for Cleavage of the Notch1 Substrate. [PDF]

ACS Chem Neurosci, 2023
Do HN, Malvankar SR, Wolfe MS, Miao Y.
europepmc   +1 more source

The manipulator behind "Scissors": γ -secretase and its modulators in Alzheimer's disease. [PDF]

Front Aging Neurosci
Ning G, Fan X, Juan D, Wenxue Z, Sijia W, Meinei C, Xiaolong D, Yiming Q.   +7 more
europepmc   +1 more source

The role of γ-secretase in familial hidradenitis suppurativa: Implications for pathogenesis and targeted therapy. [PDF]

JAAD Case Rep
Desta B, Korytnikova E, Tessier-Kay M, Klufas T, Lu J, Sarfo A, Zhou AE.   +6 more
europepmc   +1 more source

γ-Secretase-Mediated Endoproteolysis of Neuregulin-1 and E-Cadherin. [PDF]

Biochemistry
Malvankar SR, Wolfe MS.
europepmc   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Charting γ-secretase substrates by explainable AI. [PDF]

Nat Commun
Breimann S, Kamp F, Basset G, Abou-Ajram C, Güner G, Yanagida K, Okochi M, Müller SA, Lichtenthaler SF, Langosch D, Frishman D, Steiner H.   +11 more
europepmc   +1 more source

Endogenous γ-Secretase Is Linked to Phagocytic Activity in Microglial Cells. [PDF]

Sensors (Basel)
Williams E, Houser MCQ, Torres S, Wieckiewicz N, Sadek M, Yokomizo M, Maesako M.   +6 more
europepmc   +1 more source

Interaction of Substrates with γ-Secretase at the Level of Individual Transmembrane Helices-A Methodological Approach. [PDF]

Int J Mol Sci, 2023
Pauli TM, Julius A, Costa F, Eschrig S, Moosmüller J, Fischer L, Schanzenbach C, Schmidt FC, Ortner M, Langosch D.   +9 more
europepmc   +1 more source

The critical role of γ-secretase and its inhibitors in cancer and cancer therapeutics. [PDF]

Int J Biol Sci, 2023
Song C, Zhang J, Xu C, Gao M, Li N, Geng Q.   +5 more
europepmc   +1 more source

Presenilin, γ-Secretase, and the Search for Pathogenic Triggers of Alzheimer's Disease. [PDF]

Biochemistry
Wolfe MS.
europepmc   +1 more source