Results 171 to 180 of about 14,867 (279)

Palaeoproteomic Deconvolution of Physical and Genetic Collagen Mixtures

Advanced Science, EarlyView.
ClassiCOL_v2 uses a novel “peptide patching” framework that treats any collagen sample as a patchwork of peptide sequences derived from phylogenetically related species. This allows the algorithm to simultaneously resolve two previously intractable problems: multi‐species samples and/or database deficiencies.
Ian Engels, Tristan Dedrie, Synnøve K. Mo, Simon Van de Vyver, Thijs R. A. Vandenbroucke, Kévin Di Modíca, Jan Decher, Alice Toso, Dieter Deforce, Simon Daled, Alexandra Burnett, Grégory Abrams, Maarten Dhaenens   +12 more
wiley   +1 more source

CP prediction from residual Z2s and Z‾2s symmetries with the latest data

Physics Letters B
The JUNO first data and the recent neutrino global fit results are implemented in the sum rule from the residual Z2s and Z‾2s symmetries to make prediction of the leptonic Dirac CP phase δD.
Shao-Feng Ge, Chui-Fan Kong, João Paulo Pinheiro   +2 more
doaj   +1 more source

Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

Advanced Science, EarlyView.
A series of melatonin‐conjugated platinum(IV) prodrugs was functionalized with isocyanate chains (compounds 5‒12). MP‐12C (compound 11) was identified as the lead candidate, with optimal potency and safety. MP‐12C exhibited greater efficacy than cisplatin by increasing intracellular uptake, reshaping the extracellular matrix, activating the cGAS‐STING ...
Linhui Wang, Xiaomeng Liu, Tao Zhu, Zirun Su, Ruiping Liu, Zhe Li, Kaixuan Du, Kaipeng Jia, Chong Fu, Yuda Lin, Zihan Xue, Zhe Zhang, Chong Shen, Yunkai Qie, Zhouliang Wu, Zhiheng Liu, Kangkang Liu, Jingyuan Xu, Hailong Hu   +18 more
wiley   +1 more source

Strengthening Constitutive Motifs in Isotropic Fibrous Hydrogel for Exceptional Damage Resistance

Advanced Science, EarlyView.
An orientation‐free strategy is reported for fabricating damage‐resistant hydrogels by strengthening constitutive motifs in isotropic fibrous (IF) networks. Through nonsolvent quenching followed by salting‐out, IF networks are generated and their multiscale constituents are subsequently reinforced, yielding dense and crystalline isotropic nanofiber ...
Bolin Wan, Xule Yang, Liju Xu, Dong Qiu
wiley   +1 more source

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

Advanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han, Minwoo Wendy Jang, Taeyoung Park, Ki Jung Kim, Victor James Drew, Sunpil Kim, Tai Young Kim, Mingu Gordon Park, Myeongju Kim, Seung Won Chung, Minah Suh, C. Justin Lee   +11 more
wiley   +1 more source

Divergence in the absolute numbers of B lineage subpopulations from the bone marrow, spleen, and peritoneal cavity of homo- and heterozygous ΔD-DFL and ΔD-iD mice relative to their littermate controls.

, 2015
Percent loss or gain in homo- and heterozygous ΔD-DFL (top) and ΔD-iD (bottom) mice relative to wild type littermate controls in the average absolute number of cells in bone marrow fractions B (CD19+ CD43+ HSA+ BP-1-), C (CD19+ CD43+ HSA+ BP-1+), D (CD19+
Cun Ren Liu (695109), Pratibha Kapoor (695112), Ada Elgavish (695113), Robert L. Schelonka (695115), Harry W. Schroeder Jr. (695118), Gregory C. Ippolito (167860), Peter D. Burrows (695117), Andre M. Vale (695110), Mohamed Khass (695111), Trenton R. Schoeb (695116), Aaron Silva-Sanchez (5662027), Ivaylo I. Ivanov (695114)   +11 more
core   +1 more source

Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation

Advanced Science, EarlyView.
Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu, Xin Yuan, Zilong He, Hong Jin, Jiayi Tian, Cong Chen, Yuanjing Liu, Xiang Zhang, Shidan Wen, Emilio Kropff, Chenglin Miao   +10 more
wiley   +1 more source

Solvent‐Free Synthesis of Ultrabright Carbon Dots With Near‐Unity Quantum Yield for High‐Performance Light‐Emitting Diodes

Advanced Science, EarlyView.
A rational, solvent‐free synthesis utilizing 2,6‐diaminonaphthalene produces ultrabright green‐emissive carbon dots. Regulated by a self‐limiting oxidative capping mechanism, excitons undergo ultrafast intra‐particle funneling from the nitrogen‐doped carbon core to emissive surface traps.
Hyeonjin Park, Su Hwan Lee, Sejeong Seo, Soye Park, Soo min Ji, Hyunda Jo, Sehyeon Park, Young‐Hoon Kim, Woosung Kwon   +8 more
wiley   +1 more source

Peculiarities of the Frequency Dependences of the Dislocation Decrement of Ultrasound Attenuation for Ionic Crystals with Radiation Defects and Impurities

Журнал нано- та електронної фізики
An analysis of frequency dependences of dislocation decrement of ultrasound attenuation Δd(f) behavior in KBr, LiF and NaCl crystals was performed in experiments with variable temperature T and dislocation density Λ of crystals, as well as with ...
O.M. Petchenko, A.V. Bezougly, A.V. Poyda, O.M. Didenko, S.M. Boiko, G.O. Petchenko   +5 more
doaj   +1 more source

Intrafeather and Intraindividual Variation in the Stable-Hydrogen Isotope (δD) Content of Raptor Feathers [PDF]

, 2008
Stable-hydrogen isotope ratios (deuterium:protium; δD) in feathers enable researchers to evaluate patterns of avian movement and to estimate the source areas of migratory birds.
Smith, Adam D., Donohue, Kara, Dufty, Alfred M., Jr.   +2 more
core