Results 161 to 170 of about 1,820,241 (196)

κ-opioid receptor stimulation alleviates rat vascular smooth muscle cell calcification via PFKFB3-lactate signaling. [PDF]

Aging (Albany NY), 2021
Niu J, Wu C, Zhang M, Yang Z, Liu Z, Fu F, Li J, Feng N, Gu X, Zhang S, Liu Y, Fan R, Li J, Pei J.   +13 more
europepmc   +1 more source

Threonine-53 Phosphorylation of Dopamine Transporter Dictates κ-Opioid Receptor-Mediated Locomotor Suppression, Aversion, and Cocaine Reward. [PDF]

J Neurosci
Durairaj RV, Ramamoorthy S, Jayanthi LD.
europepmc   +1 more source

κ Opioid Receptor-Dynorphin Signaling in the Central Amygdala Regulates Conditioned Threat Discrimination and Anxiety. [PDF]

eNeuro, 2021
Baird MA, Hsu TY, Wang R, Juarez B, Zweifel LS.   +4 more
europepmc   +1 more source

Macrophage κ-opioid receptor inhibits hypoxic pulmonary hypertension progression and right heart dysfunction via an SCD1-dependent anti-inflammatory response. [PDF]

Genes Dis
Wang Q, Liu J, Li R, Kong S, Wang Y, Huang G, Zhang S, Feng N, Gu X, Liu Y, Jia M, Fu F, Li J, Li J, Pei J.   +14 more
europepmc   +1 more source

Efficacy and safety of peripherally-restricted κ-opioid receptor agonist-HSK21542 for postoperative analgesia in patients undergoing laparoscopic abdominal surgery: a randomized, placebo-controlled phase 2 trial. [PDF]

Front Med (Lausanne)
Zhong Y, Wang H, Yan M, Yang M, Zhang J, Nan L, Wang Z, Yang J, Wu J, Guo Q, Hu X, Xu H, Xu Q, Wang D.   +13 more
europepmc   +1 more source

Replacing a Palatable High-Fat Diet with a Low-Fat Alternative Heightens κ-Opioid Receptor Control over Nucleus Accumbens Dopamine. [PDF]

Nutrients, 2021
Wallace CW, Beatty NS, Hutcherson SA, Emmons HA, Loudermilt MC, Fordahl SC.   +5 more
europepmc   +1 more source

Retracted: κ-Opioid Receptor Agonist Ameliorates Postoperative Neurocognitive Disorder by Activating the Ca²⁺/CaMKII/CREB Pathway. [PDF]

J Healthc Eng, 2022
Healthcare Engineering JO.
europepmc   +1 more source

Identification of c[D-Trp-Phe-β-Ala-β-Ala], the First κ-Opioid Receptor-Specific Negative Allosteric Modulator. [PDF]

ACS Pharmacol Transl Sci
Zhao J, Baiula M, Cuna E, Francescato M, Matalińska J, Lipiński PFJ, Bedini A, Gentilucci L.   +7 more
europepmc   +1 more source

Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain. [PDF]

J Med Chem, 2021
Muratspahić E, Tomašević N, Koehbach J, Duerrauer L, Hadžić S, Castro J, Schober G, Sideromenos S, Clark RJ, Brierley SM, Craik DJ, Gruber CW.   +11 more
europepmc   +1 more source

κ‑opioid receptor agonist U50488H attenuates postoperative cognitive dysfunction of cardiopulmonary bypass rats through the PI3K/AKT/Nrf2/HO‑1 pathway. [PDF]

Mol Med Rep, 2021
Fan J, Li L, Qu P, Diao Y, Sun Y.
europepmc   +1 more source