Results 101 to 110 of about 109,441 (301)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Multiconfigurational Quantum Chemistry Determinations of Absorption Cross Sections (σ) in the Gas Phase and Molar Extinction Coefficients (ε) in Aqueous Solution and Air–Water Interface

, 2021
Ana Borrego‐Sánchez, Madjid Zemmouche, Javier Carmona‐García, Antonio Francés‐Monerris, Pep Mulet, Isabelle Navizet, Daniel Roca‐Sanjuán   +6 more
openalex   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Phase evolution in an Al0.5CrFeCoNiCu High Entropy Alloy [PDF]

, 2016
The phase evolution of an Al₀.₅CrFeCoNiCu High Entropy Alloy has been characterised following isothermal exposures between 0.1 and 1000 hours at temperatures of 700, 800 and 900˚C.
Christofidou, KA, Izzo, R, Jones, NG, Mignanelli, PM, Stone, HJ   +4 more
core  

T-duality in Massive Integrable Field Theories: The Homogeneous and Complex sine-Gordon Models

, 2004
The T-duality symmetries of a family of two-dimensional massive integrable field theories defined in terms of asymmetric gauged Wess-Zumino-Novikov-Witten actions modified by a potential are investigated. These theories are examples of massive non-linear
Alvarez, Alvarez, Alvarez, Alvarez, Alvarez, Alvarez, Bakas, Bakas, Barashenkov, Barashenkov, Barashenkov, Bardakci, Bars, Bowcock, Buscher, Buscher, Cabra, Cabrera-Carnero, Cabrera-Carnero, Castro Alvaredo, Castro-Alvaredo, Castro-Alvaredo, Castro-Alvaredo, Castro-Alvaredo, Castro-Alvaredo, Castro-Alvaredo, Coleman, Curtright, de Vega, de Vega, de Vega, Dijkgraaf, Dorey, Dorey, Dorey, Fateev, Felder, Fernández-Pousa, Fernández-Pousa, Fernández-Pousa, Ferreira, Ferreira, Gaberdiel, Gawedzki, Gawedzki, Getmanov, Giveon, Giveon, Goddard, Gomes, Gomes, Gomes, Gomes, Gomes, Gomes, Gomes, Gomes, Hollowood, Humphreys, J. Luis Miramontes, Karabali, Karabali, Kiritsis, Kiritsis, Korff, Kramers, Leznov, Lund, Lund, Miramontes, Park, Park, Park, Park, Pohlmeyer, Quella, Quella, Witten, Witten, Zamolodchikov, Zamolodchikov   +80 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Duplex and superduplex stainless steels: microstructure and properties evolution by surface modification processes [PDF]

, 2019
The paper presents an overview of diffusion surface treatments, especially nitriding processes, applied to duplex and superduplex stainless steels in the last five years. Research has been done mainly to investigate different nitriding processes in order
Biserova Tahchieva, Alisiya, Cabrera Marrero, José M., Llorca Isern, Núria   +2 more
core  

Critical behavior of the two dimensional 2A->3A, 4A->0 binary system

, 2004
The phase transitions of the recently introduced 2A -> 3A, 4A -> 0 reaction-diffusion model (G.Odor, PRE 69 036112 (2004)) are explored in two dimensions. This model exhibits site occupation restriction and explicit diffusion of isolated particles.
G. Ódor, G. Ódor, Géza Ódor, I. Webman, J. Marro, M. Henkel, U. Täuber   +6 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Gas‐phase detection of the HBCC (X¹Σ) molecule: a combined crossed beam and computational study of the B(²P)+C₂H₂(¹Σ_g⁺) reaction [PDF]

, 2001
Nadia Balucani, Oskar Asvany, Y. T. Lee, Ralf I. Kaiser, Nicolas Galland, M.T. Rayez, Yacine Hannachi   +6 more
openalex   +1 more source