Results 31 to 40 of about 3,121,151 (264)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Effect of Nitrogen Doping on the Structure and Mechanical Properties of the Fe₄₀Mn₄₀Cr₁₀Co₁₀ High-Entropy Alloy

Metals, 2022
The structure and mechanical properties of as-cast and thermomechanicaly processed (cold rolling followed by annealing at 700 °C and 900 °C) Fe40Mn40Cr10Co10 (at.%) high-entropy alloys doped with different amounts (0, 0.5, and 2.0 at.%) of N were ...
Anastasiia Semenyuk, Elizaveta Povolyaeva, Vitalii Sanin, Sergey Zherebtsov, Nikita Stepanov   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Phase-field simulations of intergranular stress corrosion cracking in Fe-Cr-Ni alloy incorporating σ phase precipitation

Materials & Design
σ phase is a common precipitate in Fe-Cr-Ni alloy, which may significantly influence intergranular stress corrosion cracking (IGSCC). This influence stems primarily from the compositional segregation and elastic mismatch induced by σ phase precipitation,
Qionghuan Zeng, Yiming Chen, Meirong Jiang, Zhijun Wang, Lei Wang, Junjie Li, Jincheng Wang   +6 more
doaj   +1 more source

Laser deposition additive manufacturing of 17-4PH stainless steel on Ti-6Al-4V using V interlayer

Materials Research Letters, 2019
For the first time, additive manufacturing was used to obtain a strong joint (bonding strength >200 MPa) between stainless steel and Ti-6Al-4V using a V interlayer.
Nana Kwabena Adomako, Sanghoon Noh, Chang-Seok Oh, Sangsun Yang, Jeoung Han Kim   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Effects of cold rolling on phase precipitation and phase transformation in a 2507 SDSS [PDF]

, 2011
In the present work 7 samples of UNS S32750 was cold rolled at different rates, analyzed in this state and also after the ageing for 2400s at 400 and 900°C.\nInvestigation was carry out with: OM SEM ( EBSD EDS) Magnetic tests: Forster, Permeameter ...
Bianchi, Marco
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Μικρασιατικόν Ημερολόγιον του έτους 1912. Τόμος έκτος μετ΄ εικόνων / υπό Ελένης Σ. Σβορώνου [εκδότης] [PDF]

, 1912
400 σ.: εικ.; 12χ19 ...
Σβορώνου, Ελένη Σ.
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source