Results 51 to 60 of about 3,121,151 (264)

Dynamics and conformation of Hairy-Rod Polymers in Isotropic Solutions [PDF]

, 1997
In this work we study: a)The conformation,b)the agregation, c)the dynamic behavior of Stiff Hairy -rod polymers in isotopic solutions and d)the molecular orientation i n thin films.The basic experimental techniques are based on light sca ttering: 1 ...
Πετεκίδης, Γεώργιος Σ
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Effect of Mn on σ Phase and Toughness of 22%Cr Duplex Stainless Steel by Aging Treatment at 700℃

Cailiao gongcheng, 2017
The effect of different Mn contents on the σ phase and toughness of 22%Cr (mass fraction, the same below) low-nickel DSS by means of OM, XRD, SEM, TEM, precipitation kinetics and Charpy impact tests was studied.
BAI Yu-liang, YANG Yin-hui, CAO Jian-chun, GU Yang, PU Jing   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Multi-phase System Supplied by SVM VSI: A New Fast Algorithm to Compute Duty Cycles [PDF]

, 2004
La version éditeur de cette article est disponible à l'adresse suivante : http://www.epe-association.org/epe/index.phpMany authors proposed SVM VSI applied to multi-phase ...
HAUTIER, Jean-Paul, KESTELYN, Xavier, SEMAIL, Eric   +2 more
core   +1 more source

σ-phase precipitation in weld metal of austenitic stainless steels and its effect on properties

Hanjie xuebao
Low-temperature conditions necessitate high toughness in the welded joints of austenitic stainless steel structures. However, the impact toughness of the weld metal decreases significantly when using electrodes developed for SMAW under such conditions ...
Xuegang ZHANG, Xuchao GUO, Shuaijie JIAO, Meng WANG, Yan CHEN, Tingting SUN, Pengliang HU   +6 more
doaj   +1 more source

Σ-Δ modulation analysis and optimization in fractional-N frequency synthesizer

Dianzi Jishu Yingyong, 2018
Analyzed the impaction of Σ-Δ modulation on Σ-Δ frequency synthesizer′s phase noise and spurs, and optimized Σ-Δ modulator to improve the performance of Σ-Δ frequency synthesizer.
Yang Jianming
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source