Dementia of the Alzheimer type: current state of the problem [PDF]
The current knowledge on epidemiology, diagnosis, and treatment of Alzheimer's disease and dementia of the Alzheimer type are presented. Various approaches to therapy based on current understanding of the pathogenesis of the degenerative process are ...
N.A. Tyuvina, V.V. Balabanova
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Treatment for Alzheimer's diseases [PDF]
The paper gives an update on the epidemiology, etiology, pathogenesis, prevention, and treatment of Alzheimer's disease (AD). It points out the role of acetylcholine and glutamatergic components of neurotransmission in the pathogenesis of the disease, as
Nina Arkadyevna Tyuvina +1 more
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3,5-Dimethyladamantan-1-amine Restores Short-term Synaptic Plasticity by Changing Function of Excitatory Amino Acid Transporters in Mouse Model of Spinocerebellar Ataxia Type 1 [PDF]
Introduction. Memantine is an agent that used for treatment of Alzheimer's type dementia. Memantine considerably reduces the effects of neurodegeneration, may potentially slow down the neurodegenerative changes in the cerebellum and may act as treatment ...
Alex A. Vasilev +6 more
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Neurological disorders in hypertensive patients [PDF]
Hypertension is one of the most common vascular diseases. The brain as target organs in hypertension is damaged more often and earlier. Neurological complications due to hypertension are frequently hyperdiagnosed in Russian neurological practice.
N. V. Vakhnina +2 more
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Effects of CAPAH, memantine, and rivastigmine on behavioral and cognitive functions of rats [PDF]
Relevance. Alzheimer’s disease (AD) is a neurodegenerative disease characterized by cognitive and behavioral disorders. The drugs currently used in clinical practice can slow drug development but are usually associated with lifelong use because of the ...
A. G. Ovchinnikova +5 more
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Outpatient management after severe stroke with dementia [PDF]
To render outpatient care to poststroke patients, particularly to those who have severe motor and/or speech disorders is an urgent problem in neurology. These patients have frequently cognitive and psychoemotional disorders that make rehabilitation much ...
Natalia Vyacheslavovna Pizova
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The efficiency akatinoi-memantin at treatment vascular and mixed (vascular process in the combination to Alzheimer's atrophy) dementia (24-week open clinical research) [PDF]
For the purpose of efficiency and safety studying antidemented preparation akatinoi-m em antin at vascular and mixed (vascular-atrophic) dementia the moderate and heavy degree in opened clinical research results of therapy by this preparation during 12 ...
Antokhin, E. Yu. +5 more
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The purpose of the study is expansion of a number of nitrogen-containing derivatives. [PDF]
The purpose of the study is expansion of a number of nitrogen-containing derivatives.Цель исследования – расширение ряда азотсодержащих ...
Balajants, I. P. +7 more
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Биотрансформация и фармакокинетика производных адамантана [PDF]
В обзоре дана краткая характеристика группы соединений, производных аминоадамантана, с позиций фармакологии и фармакокинетики. Представлена информация о процессах превращения адамантанов в метаболиты; закономерности фармакокинетики конкретных соединений ...
В. Жердев П. +2 more
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Клинико-экономические аспекты терапии болезни Альцгеймера в России [PDF]
Экселон ТТС обладает необходимыми клинико-экономическими характеристиками для включения в государственные программы лечения деменции. Он превосходит по показателю минимизации затрат Реминил (галантамин) и Акатинол (мемантина гидрохлорид), включенные в ...
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