Dementia of the Alzheimer type: current state of the problem [PDF]
, 2014 The current knowledge on epidemiology, diagnosis, and treatment of Alzheimer's disease and dementia of the Alzheimer type are presented. Various approaches to therapy based on current understanding of the pathogenesis of the degenerative process are ...
N.A. Tyuvina, V.V. Balabanova
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3,5-Dimethyladamantan-1-amine Restores Short-term Synaptic Plasticity by Changing Function of Excitatory Amino Acid Transporters in Mouse Model of Spinocerebellar Ataxia Type 1 [PDF]
Introduction. Memantine is an agent that used for treatment of Alzheimer's type dementia. Memantine considerably reduces the effects of neurodegeneration, may potentially slow down the neurodegenerative changes in the cerebellum and may act as treatment ...
Alex A. Vasilev +6 more
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Treatment for Alzheimer's diseases [PDF]
, 2015 The paper gives an update on the epidemiology, etiology, pathogenesis, prevention, and treatment of Alzheimer's disease (AD). It points out the role of acetylcholine and glutamatergic components of neurotransmission in the pathogenesis of the disease, as
Nina Arkadyevna Tyuvina +1 more
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Neurological disorders in hypertensive patients [PDF]
, 2016 Hypertension is one of the most common vascular diseases. The brain as target organs in hypertension is damaged more often and earlier. Neurological complications due to hypertension are frequently hyperdiagnosed in Russian neurological practice.
N. V. Vakhnina +2 more
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Effects of CAPAH, memantine, and rivastigmine on behavioral and cognitive functions of rats [PDF]
Relevance. Alzheimer’s disease (AD) is a neurodegenerative disease characterized by cognitive and behavioral disorders. The drugs currently used in clinical practice can slow drug development but are usually associated with lifelong use because of the ...
A. G. Ovchinnikova +5 more
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Outpatient management after severe stroke with dementia [PDF]
, 2013 To render outpatient care to poststroke patients, particularly to those who have severe motor and/or speech disorders is an urgent problem in neurology. These patients have frequently cognitive and psychoemotional disorders that make rehabilitation much ...
Natalia Vyacheslavovna Pizova
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Frontotemporal dementia in psychiatric practice: diagnostic and therapeutic aspects [PDF]
, 2018 Frontotemporal dementia (FTD) is a progressive neurodegenerative disorder. It begins usually in the presenile age and affects predominantly the frontal lobes and anterior temporal lobes of the brain. Currently, there are three main clinical variant of FTD:
I. V. Kolykhalov
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Современные тенденции в создании препаратов для лечения болезни Альцгеймера и их клинические испытания [PDF]
, 2018 Intracellular and extracellular accumulation of fibrillary proteins, beta-amyloid and hyperphosphorylated Tau, in patients with Alzheimer’s disease (AD) leads to chronic and progressive neurodegenerative process. Overaccumulation of aggregates results in
Bachurin, S.O. +2 more
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The efficiency akatinoi-memantin at treatment vascular and mixed (vascular process in the combination to Alzheimer's atrophy) dementia (24-week open clinical research) [PDF]
, 2010 For the purpose of efficiency and safety studying antidemented preparation akatinoi-m em antin at vascular and mixed (vascular-atrophic) dementia the moderate and heavy degree in opened clinical research results of therapy by this preparation during 12 ...
Antokhin, E. Yu. +5 more
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Биотрансформация и фармакокинетика производных адамантана [PDF]
, 2012 В обзоре дана краткая характеристика группы соединений, производных аминоадамантана, с позиций фармакологии и фармакокинетики. Представлена информация о процессах превращения адамантанов в метаболиты; закономерности фармакокинетики конкретных соединений ...
В. Жердев П. +2 more
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