Results 1 to 10 of about 1,795 (39)

Damage of the Muscle System in Covid-19

Архивъ внутренней медицины, 2021
Статья посвящена поражению мышечной системы при новой коронавирусной инфекции (COVID-19). Проведен анализ литературы российских и иностранных исследователей по внелегочным проявлениям COVID-19.
I. T. Murkamilov, K. A. Aitbaev, I. O. Kudaibergenova, V. V. Fomin, Zh. A. Murkamilova, F. A. Yusupov   +5 more
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Acute Toxicity of Hydrogel Polyhexamethylene Guanidine Hydrochloride

Acta Biomedica Scientifica, 2020
Background. Previously, we have shown that the polyhexamethylene guanidine hydrochloride hydrogel exhibits a pronounced wound healing. At the same time, no studies of the toxic effect of the hydrogel on animals have been conducted.
S. N. Lebedeva, O. S. Ochirov, M. N. Grigoryeva, S. D. Zhamsaranova, S. A. Stelmakh, D. M. Mognonov   +5 more
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Assessment of Toxic and Immunoadjuvant Properties of Nanocomposites

Acta Biomedica Scientifica, 2019
Introduction. The current direction in medicine is the creation of immunobiological preparations to increase the effectiveness of specific immunotherapy and immunoprophylaxis, containing immunomodulators in their composition.
K. M. Korytov, V. I. Dubrovina, A. B. Pyatidesyatnikova, S. A. Vityazeva, V. V. Voitkova, G. F. Prozorova, A. S. Pozdnyakov, A. A. Ivanova, S. V. Balakhonov   +8 more
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GK-2 new drug with neuroprotective properties the study of acute and chronic toxicity of the finished dosage forms

Фармакокинетика и Фармакодинамика, 2019
Resume. The paper presents the data of preclinical studies of the acute and chronic toxicity of the finished dosage form of the compound GK-2, which has neuroprotective properties.
A. V. Sorokina, S. V. Alekseeva, I. A. Miroshkina, A. V. Volkova, V. V. Zabrodina, K. S. Kachalov, I. V. Alekseev, A. D. Zaharov, P. Yu. Povarnina, A. D. Durnev   +9 more
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The study of the acute and chronic toxicity dipeptide mimetic of brain-derived neurotrophic factor GSB-106 finished dosage form

Фармакокинетика и Фармакодинамика, 2019
Resume. The study of acute and chronic toxicity of the finished dosage form (SFF) GSB-106, the active substance of which is the substituted dimeric peptide, hexamethylenediamine bis (N-monosuccinyl-L-seryl-L-lysine), which has antidepressant and ...
S. V. Alekseeva, A. V. Sorokina, A. V. Volkova, V. V. Zabrodina, I. A. Miroshkina, K. S. Kachalov, I. V. Alekseev, A. D. Zaharov, P. Yu. Povarnina, A. D. Durnev   +9 more
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Study of acute toxicity of the drug GML-1

Фармакокинетика и Фармакодинамика, 2018
Resume. Relevance. The acute toxicity evaluation is the anecessary stage of preclinical research of the new original anxiolytic drug GML-1. The present investigation aim is study of the GML-1 acute toxicity. Methods.
A. V. Sorokina, S. V. Alekseeva, I. A. Miroshkina, A. V. Volkova, A. D. Durnev   +4 more
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Acute toxicity and anthelmintic efficacy of khimedol

Российский паразитологический журнал, 2019
The purpose of the research: to study acute toxicity and anthelmintic efficacy of khimedol, a new anthelmintic preparation. Materials and methods. Khimedol, anthelmintic preparation which was received by means of streamlined synthesis in the Institute ...
K. R. Toimbetova, M. A. Arzybaev, A. B. Shakirov, A. M. Malabaeva, N. . Shyityeva   +4 more
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ACTION OF 1-VINYL-1,2,4-TRIAZOLE COPOLYMER WITH N-VINYLPIROLIDONE AND METAL-CONTAINING NANOCOMPOSITES ON FUNCTIONAL STATE OF PHAGOCYTIC CELLS

Acta Biomedica Scientifica, 2018
The creation of immuno-biological drugs to increase the effectiveness of specific immunotherapy and immunoprophylaxis is a current trend in medicine to date. Therefore, the search and development of new safe and effective artificial bioorganic complexes (
V. I. Dubrovina, S. A. Vityazeva, K. M. Korytov, A. B. Pyatidesyatnikova, V. V. Voytkova, G. F. Prozorova, A. S. Pozdnyakov, A. A. Ivanova, S. V. Balakhonov   +8 more
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ОПРЕДЕЛЕНИЕ ПАРАМЕТРОВ ТОКСИЧНОСТИ НОВОГО ПРОТИВОМИКРОБНОГО ПРЕПАРАТА ФЛУПЕТСАЛЬ 1 %

Ветеринарная патология, 2013
The article shows the results of experimental on determination of toxicity parameters of new antimicrobial chemotherapeutic medicinal product Flupetsal 1 % that contains Flurenizide.

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Synthesis, physical and chemical propaties and biological activity of amide N-allylanthranylic acid

RUDN Journal of Medicine, 2010
The amide of N-allylanthranylic acid was synthesized; the structure was confirmed by IR-, IMR- and chromate-mass spectra, the anti-inflammatory, analgesic, antipyretic, ulcer, antihypoxic activities and acute toxicity were studied.
E R Kurbatov, A B Shakirova, L M Korkodinova, S M Bass, T I Yarygina   +4 more
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