Results 11 to 20 of about 1,795 (39)

Сравнительная острая токсичность супрамолекулярных комплексов фенбендазола с использованием разных полимеров для адресной доставки

open access: yes, 2020
The purpose of the research is studying acute toxicity of supramolecular complexes of fenbendazole with different polymers obtained by mechanochemical technology as compared to the substance of the drug when administered to the stomach of white mice ...
А. И. Варламова   +1 more
semanticscholar   +1 more source

Острая токсичность алкилпроизводных 5-(фуран-2-ил, 2-метилфуран-3-ил)-4-амино-1,2,4-триазол-3-тиолов

open access: yes, 2016
The purpose of our work was the further exploration of the new 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thiol alkyl derivatives’ acute toxicity, setting some patterns of alkyl substituents influence by the Sulfur atom on the acute ...
D. M. Danilchenko, V. V. Parchenko
semanticscholar   +1 more source

ОСТРАЯ, ХРОНИЧЕСКАЯ ТОКСИЧНОСТЬ И РАЗДРАЖАЮЩЕЕ ДЕЙСТВИЕ СМ-КОМПЛЕКСА

open access: yes, 2019
The researchers elaborated pharmacological complex of SM at the Chair of Morphology, Physiology and Pharmacology atSouth-UralStateAgrarianUniversity. The complex contains butafosfan, vitamins, vitamin-like substances, selected on the basis of synergistic
A. V. Mifatkhudinov, A. S. Aleshina
semanticscholar   +1 more source

CREATING A COMPLEX ANTIBACTERIAL PREPARATION BASED ON THE DOXYCYCLINE, LACTULOSE AND BROMHEXINE

open access: yesВетеринарная патология, 2013
Combination of components in the preparation is justified. Acute toxicity data of the elaborated antibacterial complex are received. The study of preparation acute toxicity when introducing into stomach is done with white mice and broiler chickens ...
Ksenia Igorevna Sazykina   +3 more
doaj  

Determination of acute toxicity and adverse effects of high doses of prolonged use of lithium ascorbate on Wistar rats

open access: yesФармакокинетика и Фармакодинамика, 2016
Toxicity study in male Wistar albino rats showed that the LD50 of Lithium ascorbate is 6,334 g/kg which refers the substance to grade 5 toxicity (practically non toxic).
K. S. Ostrenko   +5 more
doaj  

Study of acute toxicity of the drug Tropoxin

open access: yesФармакокинетика и Фармакодинамика, 2017
It was determined endurable, toxic and fatal doses of a new original anti-migraine medicine Tropoxin in tablet form at unitary oral and intraperitoneal introduction to outbreeding white mice and rats.
A. V. Sorokina   +2 more
doaj  

Toxicity and therapeutic efficacy of injections based on еnrofloxacin and colistin

open access: yesRUDN Journal of Agronomy and Animal Industries, 2009
We studied the acute and sub-chronical toxicity of the drugs on the basis of еnrofloxacin and colistin in laboratory animals. The drug according to GOST 12.1.007-76 apply to Class 3 danger - little dangerous.
V I Parshina
doaj  

The study of acute toxicity and anabolic activity of oil of corn gern

open access: yesRUDN Journal of Medicine, 2012
The work is dedicated to the pharmacological research of acute toxicity and anabolic action of oil of corn germs. It is established that oil of corn germs is referred to the virtually non-toxic preparations and has anabolic effects.
A B Samoryadova
doaj  

Ethical implications of preclinical studies

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
Animal experiments are fundamental for the biomedical science. The development of new drugs is always associated with a large number of preclinical experiments in animals.
I. N. Tyurenkov   +4 more
doaj  

ОЦЕНКА КУМУЛЯТИВНЫХ СВОЙСТВ НОВОГО ВЕТЕРИНАРНОГО ПРЕПАРАТА «РЕКОФЕРОН АЛЬФА» НА ЛАБОРАТОРНЫХ ЖИВОТНЫХ

open access: yesВетеринарная патология, 2017
В работе была проведена оценка кумулятивных свойств нового ветеринарного пре-парата «РЕКОФЕРОН АЛЬФА» на лабораторных животных. Для определения оценки кумуля тивных свойств «РЕКОФЕРОН АЛЬФА», был применен парентеральный (внутрибрюшинный) метод введения ...
Kirill Olegovich Marinichev   +5 more
doaj  

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