Results 1 to 10 of about 483 (161)

The Prognostic Value of Cytotoxic CD8-Positive Т-Lymphocytes of the Reactive Tumor Microenvironment in Diffuse Large B-Cell Lymphoma [PDF]

Клиническая онкогематология
AIM. To assess the prognostic value of cytotoxic CD8-positive Т-lymphocytes of the reactive tumor microenvironment in diffuse large B-cell lymphoma (DLBCL). MATERIALS & METHODS. The study enrolled 124 patients with newly diagnosed DLBCL.
Elena Viktorovna Vaneeva, V. A. Rosin, D. A. Dyakonov, N. V. Glubokovskikh   +3 more
doaj   +4 more sources

CHARACTERISTICS OF SIGNALING PATHWAYS MEDIATING A CYTOTOXIC EFFECT OF DENDRITIC CELLS UPON ACTIVATED Т LYMPHOCYTES AND NK CELLS

Медицинская иммунология, 2014
. Cytotoxic/pro-apoptogenic effects of IFNα-induced dendritic cells (IFN-DCs) directed against Т-lymphocytes and NK cells were investigated in healthy donors.
T. V. Tyrinova, O. Yu. Leplina, M. A. Tikhonova, L. V. Sakhno, A. A. Ostanin, E. R. Chernykh   +5 more
doaj   +3 more sources

Т lymphocytes are key immune regulating cells

Бюллетень сибирской медицины, 2007
Phenotypical and functional heterogeneity of immune regulating subpopulations of T-lymphocytes having suppressor activity is discussed in the article. Natural regulators and inducible regulating cells are characterized in more details.
V. S. Sviridova, Ye. N. Коlogrivova, N. A. Pronina, L. V. Yeliseyeva, A. A. Chitalkina   +4 more
doaj   +3 more sources

Langerhans cells and gamma delta Т-lymphocytes in the pathogenesis of psoriasis [PDF]

Vestnik Dermatologii i Venerologii
Psoriasis is a frequently occurring inflammatory skin disease. Fundamental research into the pathogenesis of psoriasis has significantly expanded our understanding of skin immunology, which has enabled the introduction of innovative and highly effective ...
Ekaterina V. Sorokina, Eugene O. Kalinichenko, Irina V. Bisheva, Vera N. Stolpnikova   +3 more
doaj   +3 more sources

THE ROLE OF THE DIFFERENT SUBPOPULATIONS OF CD4⁺Т LYMPHOCYTES DURING PREGNANCY

Медицинская иммунология, 2016
An important role in the formation of immunological tolerance during pregnancy play T lymphocytes. In the present review discusses the characteristics of T lymphocytes, decidua and placenta, especially their migration and functional activity during ...
D. I. Sokolov, O. I. Stepanova, S. I. Selkov   +2 more
doaj   +3 more sources

Immunological effects of cerebral palsy and rehabilitation exercises in children [PDF]

Brain, Behavior, & Immunity - Health, 2021
Cerebral palsy (CP) is a group of motor disorders caused by non-progressive lesions of the premature brain with lifelong pathophysiological consequences that include dysregulation of innate immunity.
Oleksandra Sharova, Oleksandr Smiyan, Thomas Borén   +2 more
doaj   +2 more sources

EXPRESSION LEVELS OF SOME ADHESION MOLECULES IN THE INTACT AND UV-IRRADIATED Т-LYMPHOCYTES FROM HUMAN BLOOD

Медицинская иммунология, 2014
. While employing an enzyme linked immunosorbent assay, it was shown that UV-sensitivity is different for various adhesion molecules (CD2, CD11a and CD29) at the membranes of T-lymphocytes.
V. G. Artyukhov, O. V. Putintseva, S. M. Dubova   +2 more
doaj   +3 more sources

CD25+CD4+ regulatory т lymphocytes in peripheral blood of patients with prostate cancer and prostate adenoma

RUDN Journal of Medicine, 2010
CD4+CD25+ regulatory Tcells (Treg) have been shown to inhibit the activation and function of T cells that participate in antigen-specific immune responses.
N M Agaev, V P Avdoshin, Е YU Moskaleva, О N Popova, S E Severin   +4 more
doaj   +1 more source

CD3⁺CD294⁺T cells of the type 2 immune response: their role in allergic inflammation

Медицинская иммунология, 2022
T lymphocytes type 2 immune response protect against helminths and toxins, and also contribute to the development of allergic inflammation. One of the most specific T cell surface markers T lymphocytes 2 is the CRTH2 molecule (CD294), which is an ...
N. V. Bychkova
doaj   +1 more source

CAR-Т Cells for the Treatment of Chronic Lymphocytic Leukemia: Literature Review

Клиническая онкогематология, 2021
Chronic lymphocytic leukemia (CLL) is the most common adult malignant lymphoid disease. Despite new highly effective targeted drugs, the prognosis of relapsed and resistant form of this disease is poor.
Irina Vladimirovna Gribkova, A. A. Zav’yalov   +1 more
doaj   +1 more source