Results 11 to 20 of about 483 (161)

TLR7 gene effect on hepatic fibrosis progression rate in HIV-infected patients with chronic hepatitis C [PDF]

Zaporožskij Medicinskij Žurnal, 2019
The aim of the research – to optimize the prediction of hepatic fibrosis (HF) progression rate in HIV-infected patients with chronic hepatitis C (CHC) based on a comprehensive assessment of general clinical, biochemical, immunological and molecular ...
L. M. Syzova, T. I. Koval, L. P. Kotsiubailo, O. H. Marchenko   +3 more
doaj   +3 more sources

THE ROLE OF SUBPOPULATIONS OF CD8+ T LYMPHOCYTES IN THE DEVELOPMENT OF PREGNANCY [PDF]

Медицинская иммунология, 2018
At the present time, a broad spectrum of CD8+ T lymphocyte subsets is revealed, including naïve cells, memory cells and regulatory subpopulations. Along with cells with high cytolytic activity, some subsets with marked regulatory activity were found ...
O. I. Stepanova, D. O. Bazhenov, E. V. Khokhlova, I. Yu. Kogan, D. I. Sokolov, S. A. Selkov   +5 more
doaj   +3 more sources

Preclinical efficacy investigation of human neutrophil elastase inhibitor sivelestat in animal model of psoriasis. [PDF]

Skin Health Dis, 2022
Abstract Background Psoriasis is a chronic immune‐mediated inflammatory skin disease manifested by an increased rate of keratinocyte division. Currently, it has been established that the cytokines of the IL‐36 family play a significant role in the initiation and regulation of the inflammatory process in psoriasis.
Zhukov AS, Khairutdinov VR, Samtsov AV, Krasavin M, Garabadzhiu AV.   +4 more
europepmc   +2 more sources

The content of leukocytes in the blood of recipient rabbits after allogeneic transfusion of packed red blood cells [PDF]

Regulatory Mechanisms in Biosystems
Researching how the immune system reacts to stimuli such as blood transfusion of alloantigens on models of different species of laboratory animals, in particular rabbits, is important for understanding the mechanisms through which post-transfusion ...
M. О. Malyuk, O. V. Yehorov, I. O. Kharkevych, V. V. Klymchuk, T. L. Savchuk   +4 more
doaj   +3 more sources

Prolonged Inhalation Exposure to Coal Dust on Irradiated Rats and Consequences. [PDF]

ScientificWorldJournal, 2022
The purposes of this study were to research immune system changes and liver and lung tissues in irradiated rats after prolonged exposure to coal dust. A study was carried out on 30 male Wistar rats that were divided into 3 groups: group I, intact animals; group II, exposure to coal dust and 0.2 Gy γ‐irradiation; and group III, combined exposure to 6 Gy
Chulenbayeva L, Ilderbayev O, Suleymeneva D, Kaliyeva A, Kabdykanov S, Nurgaziyev M, Nurgozhina A, Sergazy S, Kozhakhmetov S, Kushugulova A.   +9 more
europepmc   +2 more sources

Immunosuppressive Phenotype of Esophagus Tumors Stroma. [PDF]

Anal Cell Pathol (Amst), 2020
Background. Tumor‐associated macrophages (TAMs) and tumor‐infiltrating lymphocytes (TILs) contribute significantly to the development of immunosuppressive properties of a tumor. In this study, we performed immunohistochemical analysis of immune cells of esophageal tumors stroma. Methods.
Kovaleva OV, Rashidova MA, Samoilova DV, Podlesnaya PA, Mochalnikova VV, Gratchev A.   +5 more
europepmc   +2 more sources

Alkylresorcinols as a New Type of Gut Microbiota Regulators Influencing Immune Therapy Efficiency in Lung Cancer Treatment

Advanced Gut &Microbiome Research, Volume 2023, Issue 1, 2023., 2023
Background. Alkylresorcinols (ARs) are polyphenolic compounds of microbial origin with a wide spectrum of biological activities and are potentially involved in host immune functioning. The present study is aimed at evaluating alterations in AR content in blood serum and faeces from healthy donors and patients with lung cancer in connection with ...
Aleksandr V. Shestopalov, Oleg I. Kit, Anastasia A. Zabolotneva, Elena Y. Zlatnik, Aleksey Yu Maksimov, Inna A. Novikova, Alexander B. Sagakyants, Sofya V. Timofeeva, Anna S. Goncharova, Anastasia V. Galina, Svetlana A. Appolonova, Pavel A. Markin, Valentin V. Makarov, Sergey M. Yudin, Anton A. Keskinov, Sergei A. Roumiantsev, Oleg I. Meshkov, Jian Wu   +17 more
wiley   +1 more source

Improvement of Possibilities of Treating Pneumonias in Patients on the Background of Acute Myeloblast Leucosis in the Aspect of Immunoresistance Mechanisms [PDF]

, 2017
Aim: to analyze the influence of the immunomodeling preparation glutamyl-cysteinyl-glycine disodium (glutoxim) on indices of cellular and humoral immunity in patients with pneumonias on the background of acute myeloblast leucosis to form new approaches ...
Borisova, I. (Inna)
core   +3 more sources

hsa‐MicroRNA‐28‐5p Inhibits Diffuse Large B‐Cell Lymphoma Cell Proliferation by Downregulating 14‐3‐3ζ Expression

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
MicroRNAs (miRNAs) participate in the comprehensive biological process of several cancer types. In our former study, we found that hsa‐microRNA‐ (miR‐)28‐5p was downregulated, but tyrosine 3‐monooxygenase/tryptophan 5‐monooxygenase activating protein zeta (14‐3‐3ζ or YWHAZ) was upregulated in diffuse large B‐cell lymphoma (DLBCL) tissues.
Shufang Yan, Yang Chen, Meihong Yang, Qian Zhang, Jiajia Ma, Bo Liu, Liuqing Yang, Xinxia Li, Hao Luo   +8 more
wiley   +1 more source

Morphological Characteristics of the Thymus and Spleen and the Subpopulation Composition of Lymphocytes in Peripheral Blood during Systemic Inflammatory Response in Male Rats with Different Resistance to Hypoxia. [PDF]

Int J Inflam, 2019
On the model of the systemic inflammatory response (SIRS), induced by lipopolysaccharide (LPS), the morphological and functional changes in the thymus and spleen and the subpopulation composition of peripheral blood lymphocytes of rats differing in resistance to hypoxia were studied.
Dzhalilova DS, Kosyreva AM, Diatroptov ME, Zolotova NA, Tsvetkov IS, Mkhitarov VA, Makarova OV, Khochanskiy DN.   +7 more
europepmc   +2 more sources