Results 81 to 90 of about 1,391 (93)

The possibility of calculating optimal doses in combined medicinal product (Working hypothesis)

open access: yesФармакокинетика и Фармакодинамика
The purpose of the study is a theoretical justification (working hypothesis) of a possible approach to calculating doses in a combined medicinal product containing 2 pharmaceutical substances.
I. B. Tsorin, S. A. Kryzhanovskii
doaj   +1 more source

Методическое пособие для студентов 2-3 курсов лечебного факультета по подготовке к занятиям по общей хирургии [PDF]

open access: yes, 2015
методические пособия; общая хирургия; ситуационные задачи; тестовые задачи; пособияВ пособие включены основные материалы, необходимые для студентов при подготовке к практическим занятиям на 2-3 курсах лечебного факультета по общей хирургии.
Небылицин, Ю. С.   +3 more
core  

Assessment of the influence of demographic and anthropometric indicators on the variability of pharmacokinetic parameters

open access: yesФармакокинетика и Фармакодинамика
Relevance. Planning the design of bioequivalence clinical studies of generic highly variable drugs requires non-standard approaches – the use of replicative (repeated) or adaptive design.
V. B. Vasilyuk   +3 more
doaj   +1 more source

Effect of cyclo-L-prolylglycine on pain response thresholds and morphine-induced analgesia in inbred BALB/c and C57Bl/6 mice

open access: yesФармакокинетика и Фармакодинамика
Relevance. Cyclo-L-prolylglycine (CPG), discovered as an endogenous compound in the central nervous system, is involved in the formation of a reaction to emotional stress in rodents with a pronounced fear reaction and has an analgesic effect in vivo ...
A. V. Nadorova   +3 more
doaj   +1 more source

Анализ лёгкой пептидной фракции Лаеннека методами современной протеомики [PDF]

open access: yes, 2016
Laennec preparation is based on standardized human placenta hydrolyzate and is highly effective in the regeneration of tissues. This study presents the results of analysis of the light peptide fraction of Laennec (Препарат Лаеннек основан на ...
I. I. Baranov   +15 more
core   +1 more source

Ferroptosis and ageing

open access: yesФармакокинетика и Фармакодинамика
Ferroptosis is a regulated form of cell death characterized by iron-dependent lipid peroxidation. Since its initial description, it has garnered significant attention due to its implications in various diseases, including cancer, neurodegeneration, and ...
A. A. Garanin   +2 more
doaj   +1 more source

Методическое пособие для преподавателей по проведению занятий по общей хирургии на 3 курсе лечебно-профилактического факультета [PDF]

open access: yes, 2003
МЕТОДИЧЕСКИЕ ПОСОБИЯАСЕПТИКААНТИСЕПТИКАПЕРЕЛИВАНИЕ КРОВИХИРУРГИЧЕСКИЕ ОПЕРАЦИИИНФЕКЦИЯ ХИРУРГИЧЕСКАЯОБЩАЯ ХИРУРГИЯВключены основные материалы, необходимые для преподавателя при проведении практических занятий на 3 курсе по общей хирургии.
Болобошко, К. Б.   +5 more
core  

Study of the possibility of using metformin by intranasal administration for the correction of behavioral and cognitive dysfunctions of rats

open access: yesФармакокинетика и Фармакодинамика
Relevance. Metformin is an antidiabetic agent in the therapy of type 2 diabetes mellitus, which has a complex of pharmacological effects that may allow its use as a geroprotector and a means for the treatment of cognitive and behavioral disorders ...
A. Z. Hafizova, I. I. Semina
doaj   +1 more source

Определение острой токсичности и негативного воздействия высоких доз аскорбата лития при длительном применении на крысах линии Вистар [PDF]

open access: yes, 2016
Toxicity study in male Wistar albino rats showed that the LD50 of Lithium ascorbate is 6,334 g/kg which refers the substance to grade 5 toxicity (practically non toxic).
A. Pronin V.   +11 more
core   +1 more source

Valsartan pharmacokinetics in patients with controlled and uncontrolled arterial hypertension

open access: yesФармакокинетика и Фармакодинамика
Relevance. Arterial hypertension (AH) is widespread throughout the world. Unfortunately, only a small proportion of patients achieve target blood pressure (BP).
S. V. Seleznev   +2 more
doaj   +1 more source

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