Results 1 to 9 of about 9 (9)

Study of acute toxicity of potential anxiolytic GML-1

Фармакокинетика и Фармакодинамика, 2019
Relevance. Assessment of chronic toxicity is a necessary stage of preclinical research of a newly synthesized pharmacological substance GML-1 having anxiolytic activity.
I. A. Miroshkina, A. V. Sorokina, A. V. Volkova, K. S. Kachalov, I. V. Alekseev, A. D. Zaharov, S. V. Alekseeva, A. D. Durnev   +7 more
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GK-2 new drug with neuroprotective properties the study of acute and chronic toxicity of the finished dosage forms

Фармакокинетика и Фармакодинамика, 2019
Resume. The paper presents the data of preclinical studies of the acute and chronic toxicity of the finished dosage form of the compound GK-2, which has neuroprotective properties.
A. V. Sorokina, S. V. Alekseeva, I. A. Miroshkina, A. V. Volkova, V. V. Zabrodina, K. S. Kachalov, I. V. Alekseev, A. D. Zaharov, P. Yu. Povarnina, A. D. Durnev   +9 more
doaj   +1 more source

The study of the acute and chronic toxicity dipeptide mimetic of brain-derived neurotrophic factor GSB-106 finished dosage form

Фармакокинетика и Фармакодинамика, 2019
Resume. The study of acute and chronic toxicity of the finished dosage form (SFF) GSB-106, the active substance of which is the substituted dimeric peptide, hexamethylenediamine bis (N-monosuccinyl-L-seryl-L-lysine), which has antidepressant and ...
S. V. Alekseeva, A. V. Sorokina, A. V. Volkova, V. V. Zabrodina, I. A. Miroshkina, K. S. Kachalov, I. V. Alekseev, A. D. Zaharov, P. Yu. Povarnina, A. D. Durnev   +9 more
doaj   +1 more source

ОПРЕДЕЛЕНИЕ ПАРАМЕТРОВ ТОКСИЧНОСТИ НОВОГО ПРОТИВОМИКРОБНОГО ПРЕПАРАТА ФЛУПЕТСАЛЬ 1 %

Ветеринарная патология, 2013
The article shows the results of experimental on determination of toxicity parameters of new antimicrobial chemotherapeutic medicinal product Flupetsal 1 % that contains Flurenizide.

doaj  

MORPHOLOGICAL CHANGES IN ORGANS AND TISSUES AT SUBCHRONIC INTOXICATION WITH BENZODIAZEPINE MEDICATIONS (EXPERIMENTAL RESEARCHES)

Acta Biomedica Scientifica, 2012
Morphological changes in tissues and organs at subchronic intoxication of white rats with 1,4-benzodiazepines synthetic medications (alprazolame, mezapame, diazepame, and nozepame) are studied in an experiment.
V. V. Zakharenkov, L. G. Gorokhova, O. I. Bondarev, M. S. Bugaeva   +3 more
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Experimental study of chronic toxicity and anti-inflammatory properties of the drug Dilept

Фармакокинетика и Фармакодинамика, 2016
The purpose of this study is to evaluate the chronic toxicity of the drug dilept upon a daily orally administration for 6 months at doses of 16 and 160 mg/kg.
S. V. Alekseeva, A. V. Sorokina, I. A. Miroshkina, O. S. Kuznestova, L. P. Kovalenko, A. D. Durnev   +5 more
doaj  

Experimental study of chronic toxicity and allergenic properties of the drug afobazol

Фармакокинетика и Фармакодинамика, 2016
The study of chronic toxicity injection form afobazol with daily intravenous administration for 2 weeks old female and male rats in doses of 0,1; 1; 5 and 50 mg/kg, female and male rabbits at doses of 0,1; 1 and 10 mg/kg.
S. V. Alekseeva, A. V. Sorokina, L. P. Kovalenko, I. A. Miroshkina, A. D. Durnev   +4 more
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[FGF23 tumor induced osteomalacia]. [PDF]

Probl Endokrinol (Mosk), 2022
Gronskaia SA, Belaya ZE, Melnichenko GA.
europepmc   +1 more source

[The history of the pharmacotherapy of obesity]. [PDF]

Probl Endokrinol (Mosk)
Berkovskaya MA, Gurova OY, Surkova EV, Fadeev VV.   +3 more
europepmc   +1 more source