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Subchronic and Chronic Toxicity Assessment of Sublancin in Sprague–Dawley Rats [PDF]

open access: yesToxics
Sublancin, an S-linked antimicrobial (glycol) peptide produced by Bacillus subtilis, has emerged as a novel and promising veterinary drug due to its unique antibacterial mechanism, low risk of resistance, and properties that modulate the immune system ...
Yong Guo   +5 more
doaj   +2 more sources

Chronic Salicylate Toxicity Simulation [PDF]

open access: yesMedEdPORTAL, 2018
Introduction Chronic salicylate toxicity is an uncommon, potentially life-threatening poisoning that requires high clinical suspicion in order to make the diagnosis.
Mary Wittler   +2 more
doaj   +3 more sources

Safety of Oral Carica papaya L. Leaf 10% Ethanolic Extract for Acute and Chronic Toxicity Tests in Sprague Dawley Rats [PDF]

open access: yesToxics
Carica papaya L. leaves, traditionally utilized in dietary supplements and pharmaceuticals, exhibit a broad spectrum of potentially therapeutic properties, including anti-inflammatory, antimalarial, and wound healing properties.
Weerakit Taychaworaditsakul   +7 more
doaj   +2 more sources

Thai rice instant granules containing turmeric extract and Phyllanthus emblica fruit pulp: Chronic toxicity and antioxidant profiles in rats and in silico investigation of bioactive compounds [PDF]

open access: yesFrontiers in Toxicology
Turmeric (Curcuma longa) and Indian gooseberry (Phyllanthus emblica) are widely used for their ethnopharmacological properties, particularly in ASEAN countries. Recently, our group has formulated Thai rice instant granules containing turmeric extract and
Charatda Punvittayagul   +7 more
doaj   +2 more sources

Acute and Chronic Effects of the Antifouling Booster Biocide Diuron on the Harpacticoid Copepod Tigriopus japonicus Revealed through Multi-Biomarker Determination

open access: yesJournal of Marine Science and Engineering, 2023
Diuron, an additive biocide in antifouling paints, is widely employed to curtail the attachment of organisms on submerged surfaces in aquatic structures.
Young-Joo Yun   +3 more
doaj   +1 more source

Considerations on the applicability of OECD TG 453 to whole food/feed testing [PDF]

open access: yesEFSA Journal, 2013
Upon request from the European Commission, the European Food Safety Authority prepared a scientific report that would aid the future establishment of protocols for chronic toxicity and/or carcinogenicity studies in rodents with whole food/feed.
European Food Safety Authority
doaj   +1 more source

Ecological Risk Assessment of Amoxicillin, Enrofloxacin, and Neomycin: Are Their Current Levels in the Freshwater Environment Safe?

open access: yesToxics, 2021
Veterinary pharmaceuticals may cause unexpected adverse effects on non-target aquatic species. While these pharmaceuticals were previously identified as priority compounds in ambient water, their ecological risks are relatively unknown.
Sangwoo Lee   +7 more
doaj   +1 more source

Study on the chronic toxicity and carcinogenicity of iron-based bioabsorbable stents

open access: yesNanotechnology Reviews, 2023
Fe-based stents have been made a figure in biodegradable stents by their good mechanical capacity and biocompatibility, appropriate strength–ductility combination. Although the iron corrosion rate was not ideal, which had been optimized by iron alloy and
Shi Xiaoli   +8 more
doaj   +1 more source

Chronic Toxicity Study on Deinococcus Radiodurans R1 in Rats

open access: yesShiyan dongwu yu bijiao yixue, 2021
ObjectiveTo observe the chronic toxicity of Deinococcus radiodurans R1 (DRR1) in SD rats.MethodsSD rats were divided randomly into 5 groups: 109/mL live DRR1 group (LDRH), 107/mL live DRR1 group (LDRL), 109/mL DRR1 broken products group (BDRH), 107/mL ...
XU Qin   +9 more
doaj   +1 more source

INVESTIGATION OF CHRONIC TOXICITY OF A PHARMACOLOGICAL COMPOSITION BASED ON BACTERIOCIN-NISIN AND SILICON GLYCEROLATES

open access: yesSiberian Journal of Life Sciences and Agriculture, 2023
The use of new drugs on productive animals is possible only after identifying the long-term effects of the use of substances included in the composition on the functional state of organs, tissues and systems.
Maria N. Isakova   +4 more
doaj   +1 more source

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