Zhongshan Daxue xuebao. Yixue kexue ban, 2015 摘 要: 【目的】 了解我国华南地区从未接受任何抗病毒治疗的慢性丙型肝炎(慢丙肝)患者NS3/4A蛋白酶抑制剂相关耐药位点的流行情况?临床特点包括其对干扰素联合利巴韦林抗病毒治疗的影响?【方法】 在接受抗病毒治疗前对183例慢丙肝患者的NS3/4A蛋白酶抑制剂相关的耐药位点采用自行设计型别特异性引物行巢式PCR,PCR产物纯化后直接测序法鉴定,有变异的患者为变异组(125例),无变异的患者为野生组(37例),对两组患者的临床资料包括干扰素联合利巴韦林抗病毒治疗后的持续病毒应答率等进行分析?
doaj
[Advances in the construction and application of a novel liver organoid model for hepatitis B virus infection]. [PDF]
Zhonghua Gan Zang Bing Za ZhiLi H, Xiang KH.
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[The Influence of Hepatitis B Virus on Sex Hormone Levels and Quality of Life in Female Hepatitis B Patients With Different Alanine Aminotransferase States]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanGao P, Zhou W, Li J, Yao L.
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Linchuang shenzangbing zazhi, 2013 目的 观察恩替卡韦联合糖皮质激素治疗乙型肝炎(乙肝)病毒相关性肾炎的临床效果。方法 选取在我完住院的乙肝病毒相关性肾炎患者65例,将患者随机分成2组。单一抗病毒组30例,单用恩替卡韦抗病毒治疗。联合治疗组35例,恩替卡韦抗病毒联合适量、短期糖皮质激素治疗。2组均给予常规护肝、降酶及保护肾功能治疗。对所有患者治疗前、后乙肝病毒DNA、肝功能、肾功能、血尿常规进行测定。结果 在抗病毒、护肝方面,治疗12个月后,2组血清乙肝病毒DNA载量及丙氨酸氨基转移酶、天冬氨酸氨基转移酶水平下降幅度均无明显差异 ...
doaj
[Gut microbiota-associated metabolites with drug-induced liver injury]. [PDF]
Zhonghua Gan Zang Bing Za ZhiGao WK +5 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】 探讨慢性丙型肝炎(CHC)与糖尿病(DM)的关系及其相关因素?【方法】 对200例CHC并DM患者(CHC+DM组)与242例CHC不合并DM患者(CHC组)的谷丙转氨酶(ALT)?谷草转氨酶(AST)?γ-谷氨酰转肽酶(GGT)?总胆红素(TB)?空腹血糖?空腹胰岛素?血甘油三酯及血清丙型肝炎病毒(HCV)RNA等相关指标进行检测?分析,比较两组之间各指标的差异,并将CHC+DM组分为携带者?轻度?中度?重度及不同年龄段进行对照比较,探讨CHC易发生DM的相关因素?【结果】 ①CHC ...
doaj
[Reflections on the novel definition and whether or not antiviral therapy for inactive HBsAg carrier state in the "Guidelines for the Prevention and Treatment of Chronic Hepatitis B (version 2022)"]. [PDF]
Zhonghua Gan Zang Bing Za ZhiRen S, Zheng SJ, Chen XY.
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[Analysis of antiviral efficacy in pediatric patients with HBeAg-negative chronic hepatitis B]. [PDF]
Zhonghua Gan Zang Bing Za ZhiGuo X +8 more
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[Comparison of antiviral efficacy of nucleos(t)ide analogue monotherapy and its combination with interferon-α in children 1-6 years-old with HBeAg-positive chronic hepatitis B]. [PDF]
Zhonghua Gan Zang Bing Za ZhiWang ZW +11 more
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[Research progress on the multidimensional regulation of gut microbiota on metabolism, immunity, and inflammatory response in metabolic associated fatty liver disease]. [PDF]
Zhonghua Gan Zang Bing Za ZhiWu ST, Lu XL.
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