[Thiotepa-containing conditioning for allogeneic hematopoietic stem cell transplantation in children with inborn errors of immunity: a retrospective clinical analysis]. [PDF]
Wu XJ +9 more
europepmc +1 more source
丙型肝炎病毒核心蛋白对肝癌细胞stat3通路及细胞周期蛋白cyclin D1的调控作用
【目的】 探讨丙型肝炎病毒核心蛋白(HCVc)是否调控肝癌细胞中stat3通路及细胞周期蛋白cyclin D 1的表达,参与肝癌细胞的恶性生物学行为。【方法】 将含HCVc基因的真核表达质粒pEGFP-N3-HCVc瞬时转染人肝癌细胞HepG2使HCVc过表达,用siRNA-HCVc敲除HepG2细胞中HCVc的表达,荧光显微镜检测绿色荧光蛋白(GFP)的表达,Western blot检测HCVc、总stat3(stat3)、磷酸化stat3(p-stat3)及cyclin D1蛋白的表达 ...
doaj
[Expert consensus on the diagnosis, treatment, and prevention of neonatal dengue, chikungunya, and Zika virus infections (2025)]. [PDF]
Perinatal Group +2 more
europepmc +1 more source
[Effect of the combination of alkaloids from Euodiae Fructus and berberine in Zuojin Pill on cytotoxicity in HepG2 cells]. [PDF]
Gao Y, Zhu A, Li L, Li Y, Wang Q.
europepmc +1 more source
同一份血清中的HBVDNA与HCVRNA经热变性直接法一步裂解,先用针对HCV特异的外引物将HCVRNA逆转录为cDNA,然后采用HBV,HCV各自特异的2套引物进行PCR同步扩增。结果按预定大小,PCR产物出现2条带。分别为428bp,144bp。将产物转移至尼龙膜上,经α-32PdCTP标记HCV探针及地高辛素标记HBV探针进行重复杂交,证明144bp为HCV所特有,428bp为HBV特有。用该方法对30份单独检测证实HBV,HCV核酸均阳性血清测验,其结果完全吻合、该二联技术可明显缩短检测时间 ...
doaj
[Disrupting atherosclerotic plaque formation <i>via</i> the "<i>qi</i> meridian-blood channel": mechanism of <i>Jiangzhi Huaban</i> Decoction for regulating hepatic reverse cholesterol transport to improve atherosclerosis]. [PDF]
Wang H +8 more
europepmc +1 more source
[Protective effect of knock-down the expression of <i>Blimp1</i> gene on early liver injury in CCl<sub>4</sub>-induced mouse model of liver fibrosis]. [PDF]
Qin Q +5 more
europepmc +1 more source
[Vitexin-4 ″-<i>O</i>-glucoside alleviates acetaminophen-induced acute liver injury]. [PDF]
Dong F, Lai S, Qiu J, Dou X.
europepmc +1 more source
【目的】分析地区聚集性感染事件中HCV感染者的HCV 基因型分布及进化特点,推断其传播途径。【方法】研究组192个样本,126人来自响水街的一个小区域(以ZJBL命名),均有在响水街某诊所接受医疗护理的病史,66个样本取自紫金县周边地区(以ZJ初始)。采用多片段巢式PCR 法,检测研究组HCV感染者的HCV 基因型;应用病例对照研究方法比较其他地区同基因型HCV感染者的分布特点,推断HCV的可能感染途径。【结果】192 例患者中,66例为基因亚型2a, 119例为基因亚型6a,未发现其他的基因亚型 ...
doaj
[A case of hepatitis-associated aplastic anemia complicated by hemophagocytic lymphohistiocytosis and literature review]. [PDF]
Zhou X, Chen XY, Wen C, Luo SL.
europepmc +1 more source

