Results 11 to 20 of about 3,053 (89)
Highlights Increased glutamate is associated with the development of diabetes. Glutamate increases plasminogen (PLG) levels through glutamate metabotropic receptor 5 activation with various insulin resistance‐related stresses. Glutamate inhibits the conversion of PLG to plasmin by increasing plasminogen activator inhibitor‐1.
Hyo Jung Lee +7 more
wiley +1 more source
ABSTRACT Infected bone defects represent a dual therapeutic challenge demanding concurrent infection inhibition and osteogenesis promotion. Systemic antibiotic administration is taken as a classical treatment protocol but often yields inadequate local antibiotic concentrations and delayed bone repair.
Xucai Wang +8 more
wiley +1 more source
ABSTRACT Bone restoration is often hindered by the spatiotemporal dysregulation of immune and regenerative signals. Conventional bio‐inert implants, providing only passive support, fail to modulate this microenvironment, leading to infections and poor healing.
Zhizhong Sun +8 more
wiley +1 more source
ABSTRACT Thermo‐responsive hydrogels based on poly(N‐isopropylacrylamide) (PNIPAM) are promising candidates for soft actuation, yet their practical applications are often constrained by sluggish thermo‐responsive kinetics and insufficient mechanical robustness.
Hui Liu +5 more
wiley +1 more source
ABSTRACT The development of high‐voltage aqueous zinc‐ion batteries (AZIBs) is primarily hindered by the lack of suitable cathode materials and electrolytes that can work in broad voltage windows. Herein, we propose a synergistic strategy that concurrently addresses these challenges through the integration of an amorphous vanadium oxyphosphate/graphene
Xianyu Liu +7 more
wiley +1 more source
ABSTRACT Sodium metal batteries (SMBs) are regarded as promising candidates for next‐generation energy storage systems owing to their high theoretical energy density and low cost. However, their practical development is hindered by the instability of the electrode–electrolyte interphase (EEI), particularly under high‐voltage operation.
Xingyu Yang +10 more
wiley +1 more source
ABSTRACT Aqueous vanadium dioxide (VO2)‐based smart thermal insulation coatings represent a viable strategy to decrease building energy consumption and advance sustainable development goals. However, the inherent instability and limited compatibility with polymer matrices of VO2 hinder its widespread application.
Xiuxian Zhao +9 more
wiley +1 more source
ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu +13 more
wiley +1 more source
ABSTRACT Objectives Placental insufficiency contributes to many obstetric pathologies, but there is no bedside clinical tool to evaluate placental perfusion. We have developed a method to acquire multiple three‐dimensional (3D) power Doppler (PD) ultrasound (US) volumes of placental vasculature, with infrared camera tracking of the precise spatial ...
A. Xue +5 more
wiley +1 more source
Topical and transdermal botanical formulations of the Chinese pharmacopoeia—A review
Abstract In pharmaceutics, ingredients are classified as active ingredients and excipients. In topical/transdermal phytomedicines, an ingredient may serve both functions. Published information on these dual‐purpose ingredients and their pharmacological relevance is limited.
Jingyi Gu +3 more
wiley +1 more source

